1995
Antenatal steroids, delivery mode, and intraventricular hemorrhage in preterm infants
Ment L, Oh W, Ehrenkranz R, Philip A, Duncan C, Makuch R. Antenatal steroids, delivery mode, and intraventricular hemorrhage in preterm infants. American Journal Of Obstetrics And Gynecology 1995, 172: 795-800. PMID: 7892866, DOI: 10.1016/0002-9378(95)90001-2.Peer-Reviewed Original ResearchConceptsEarly intraventricular hemorrhageAntenatal steroidsIntraventricular hemorrhageCesarean sectionPreterm infantsAntenatal steroid treatmentCesarean section deliveryHours of lifeMore vaginal deliveriesDelivery modePostnatal indomethacinSection deliveryWeight infantsSteroid treatmentVaginal deliveryHemorrhageInfantsSteroidsIndependent roleHoursDeliveryMulticenterIndomethacinTrialsEchoencephalography
1993
Intraventricular Hemorrhage and Prematurity
Duncan C, Ment L. Intraventricular Hemorrhage and Prematurity. Neurosurgery Clinics Of North America 1993, 4: 727-734. PMID: 8241793, DOI: 10.1016/s1042-3680(18)30562-x.Peer-Reviewed Original ResearchConceptsIntraventricular hemorrhageRisk of hemorrhageCerebral blood flowGerminal matrix tissueDiagnostic imaging techniquesPosthemorrhagic hydrocephalusPreterm neonatesClinical manifestationsBlood flowVentricular systemHemorrhageCapillary bedMatrix tissueImaging techniquesPossible rupturePrematurityHydrocephalusNeonatesNeuropathologyParenchymaBrain
1989
Thromboxane synthesis inhibitor in a beagle pup model of perinatal asphyxia.
Ment L, Stewart W, Petroff O, Duncan C. Thromboxane synthesis inhibitor in a beagle pup model of perinatal asphyxia. Stroke 1989, 20: 809-814. PMID: 2728050, DOI: 10.1161/01.str.20.6.809.Peer-Reviewed Original ResearchConceptsCerebral blood flowThromboxane synthesis inhibitorBlood flowPerinatal asphyxiaSynthesis inhibitorCGS 13080Intraventricular hemorrhageLactate levelsCerebral regionsHigh incidenceMetabolic alterationsWhite matterLactate concentrationAsphyxiaBrain extractsInsultPhosphocreatine concentrationPupsSalineInhibitorsHemorrhageProstaglandinsMedulla
1985
Intraventricular hemorrhage in a term neonate secondary to a third ventricular AVM. Case report.
Heafner M, Duncan C, Kier E, Ment L, Scott D, Kolaski R, Sorgen C. Intraventricular hemorrhage in a term neonate secondary to a third ventricular AVM. Case report. Journal Of Neurosurgery 1985, 63: 640-3. PMID: 3875699, DOI: 10.3171/jns.1985.63.4.0640.Peer-Reviewed Original ResearchConceptsIntraventricular hemorrhageUncomplicated full-term gestationsFull-term neonatesFull-term gestationDays of lifeMonths of ageDigital subtraction arteriographyDays of ageAcute onsetPostoperative courseTerm neonatesHealthy infantsSeizure disorderArteriovenous malformationsDifferential diagnosisThird ventricleComputerized tomographyYoung infantsHemorrhageArteriographyAngiomaNeonatesInfantsDiagnosisAgeNeurodevelopmental assessment of very low birth weight neonates: Effect of germinal matrix and intraventricular hemorrhage
Ment L, Scott D, Ehrenkranz R, Duncan C. Neurodevelopmental assessment of very low birth weight neonates: Effect of germinal matrix and intraventricular hemorrhage. Pediatric Neurology 1985, 1: 164-168. PMID: 3880401, DOI: 10.1016/0887-8994(85)90058-x.Peer-Reviewed Original ResearchConceptsGMH/IVHIntraventricular hemorrhageNeurodevelopmental assessmentGerminal matrixSurviving infantsNeonatal germinal matrix hemorrhageNewborn Special Care UnitLow birth weight neonatesBirth weight neonatesGerminal matrix hemorrhageMajor neurologic abnormalitiesSpecial care unitsNon-hemorrhage groupWeight neonatesCare unitGroup infantsPostnatal hoursNeurologic abnormalitiesBirth weightSevere gradesHemorrhageDevelopmental scoresBayley ScalesInfantsInfant developmentBeagle puppy model of intraventricular hemorrhage. Effect of superoxide dismutase on cerebral blood flow and prostaglandins.
Ment L, Stewart W, Duncan C. Beagle puppy model of intraventricular hemorrhage. Effect of superoxide dismutase on cerebral blood flow and prostaglandins. Journal Of Neurosurgery 1985, 62: 563-9. PMID: 3973726, DOI: 10.3171/jns.1985.62.4.0563.Peer-Reviewed Original ResearchConceptsCerebral blood flowIntraventricular hemorrhageProstaglandin levelsBlood flowSuperoxide dismutaseCarbon-14-iodoantipyrine autoradiographyIncidence of IVHSystemic blood pressure changesBaseline cerebral blood flowLocal cerebral blood flowDetermination of CBFBlood pressure changesSaline-pretreated animalsBeagle puppy modelNewborn beagle pupsGerminal matrix tissueHypotensive insultFree radical scavengerPreterm neonatesIodoantipyrine autoradiographyPuppy modelBeagle pupsCapillary morphologyInsultHemorrhagePerinatal Cerebral Insults: Hemorrhage and Ischemia
Ment L, Duncan C, Stewart W. Perinatal Cerebral Insults: Hemorrhage and Ischemia. Pediatric Neurosurgery 1985, 12: 168-174. PMID: 3916368, DOI: 10.1159/000120242.Peer-Reviewed Original ResearchConceptsMajor neurodevelopmental handicapsCerebral blood flowNeurodevelopmental handicapParenchymal involvementCerebral infarctionPreterm infantsIntraventricular hemorrhageGestational ageIschemic insultPerinatal careHigh riskBlood flowHemorrhageInfantsDevelopmental abnormalitiesCareInfarctionIschemiaNeonatesLesionsAbnormalitiesIncidenceInsultSurvivorsBrain
1984
Perinatal cerebral infarction
Ment L, Duncan C, Ehrenkranz R. Perinatal cerebral infarction. Annals Of Neurology 1984, 16: 559-568. PMID: 6508239, DOI: 10.1002/ana.410160506.Peer-Reviewed Original ResearchConceptsPerinatal cerebral infarctionCerebral infarctionNeonatal intraventricular hemorrhageFull-term infantsMonths of ageTwelve-month intervalsPerinatal asphyxiaPreterm neonatesIntraventricular hemorrhageNeonatal seizuresTomographic scanCommon causePostmortem examinationInfarctionInfantsStrokeAsphyxiaHemorrhageNeonatesSeizuresUteroDiagnosisMonthsDelayed Hemorrhagic Infarction: A Cause of Late Neonatal Germinal Matrix and Intraventricular Hemorrhage
Ment L, Ehrenkranz R, Duncan C, Lange R. Delayed Hemorrhagic Infarction: A Cause of Late Neonatal Germinal Matrix and Intraventricular Hemorrhage. JAMA Neurology 1984, 41: 1036-1039. PMID: 6477210, DOI: 10.1001/archneur.1984.04050210034010.Peer-Reviewed Original ResearchConceptsCerebral blood flowLow cerebral blood flowLate intraventricular hemorrhageIntraventricular hemorrhageFirst postnatal dayMonths of ageSeries of insultsProfound hypotensionPorencephalic cystPostnatal eventsGerminal matrixPostnatal dayBlood flowHemorrhageNeonatesTomographic evidenceInfarcted tissueHypotensionTissueAsphyxiaEncephalomalaciaInfarctionInfantsCystsInsultPROSTAGLANDIN-MEDIATED CONTROL OF NEONATAL CEREBRAL BLOOD FLOW
Ment L, Stewart W, Duncan C, Pitt B. PROSTAGLANDIN-MEDIATED CONTROL OF NEONATAL CEREBRAL BLOOD FLOW. Pediatric Research 1984, 18: 380-380. DOI: 10.1203/00006450-198404001-01722.Peer-Reviewed Original ResearchCerebral blood flowNeonatal cerebral blood flowIntraventricular hemorrhageNewborn beagle pupsBP changesCBF changesBeagle pupsBlood flowSuperoxide dismutaseBaseline cerebral blood flowNeonatal intraventricular hemorrhageCyclo-oxygenase pathwaySynthesis of TxB2Free radical scavengerPreterm neonatesHemorrhagic hypotensionCapillary changesIndomethacinPupsSynthetic enzymesAlterationsBreakdown productsHypotensionHemorrhageNeonatesBeagle puppy model of intraventricular hemorrhage. Effect of indomethacin on local cerebral glucose utilization.
Ment L, Stewart W, Duncan C, Scott D, Lambrecht R. Beagle puppy model of intraventricular hemorrhage. Effect of indomethacin on local cerebral glucose utilization. Journal Of Neurosurgery 1984, 60: 737-42. PMID: 6707743, DOI: 10.3171/jns.1984.60.4.0737.Peer-Reviewed Original ResearchConceptsLocal cerebral glucose utilizationCerebral glucose utilizationIntraventricular hemorrhageSaline-pretreated animalsNewborn beagle puppiesBeagle puppiesGlucose utilizationIncidence of IVHBlood pressure responseNeonatal intraventricular hemorrhageEffect of indomethacinBeagle puppy modelCerebral metabolismPuppy modelGerminal matrixWhite matterIndomethacinMarked alterationsInsultSignificant alterationsPressure responseHemorrhagePupsPuppiesAlterations
1983
Beagle puppy model of intraventricular hemorrhage. Effect of indomethacin on cerebral blood flow.
Ment L, Stewart W, Duncan C, Scott D, Lambrecht R. Beagle puppy model of intraventricular hemorrhage. Effect of indomethacin on cerebral blood flow. Journal Of Neurosurgery 1983, 58: 857-62. PMID: 6854378, DOI: 10.3171/jns.1983.58.6.0857.Peer-Reviewed Original ResearchConceptsCerebral blood flowIntraventricular hemorrhageNewborn beagle puppiesBeagle puppiesBlood flowDetermination of CBFBlood pressure responseNeonatal intraventricular hemorrhageEffect of indomethacinBeagle puppy modelNewborn beagle pupsPuppy modelBeagle pupsIndomethacinProstaglandin synthetaseInsultPupsFormer groupSignificant alterationsPressure responseHemorrhagePuppiesSalineGroupBeagle puppy model of intraventricular hemorrhage: randomized indomethacin prevention trial.
Ment L, Stewart W, Scott D, Duncan C. Beagle puppy model of intraventricular hemorrhage: randomized indomethacin prevention trial. Neurology 1983, 33: 179-84. PMID: 6681659, DOI: 10.1212/wnl.33.2.179.Peer-Reviewed Original ResearchConceptsIntraventricular hemorrhageNewborn beagle puppiesBeagle puppiesBlood pressure responseNeonatal intraventricular hemorrhageBeagle puppy modelPrevention trialsHemorrhagic hypotensionPuppy modelSaline vehicleControl animalsHemorrhageProstaglandin synthetaseExperimental modelIndomethacinSignificant alterationsPressure responsePuppiesPostpartum Perfusion of the Preterm Brain: Relationship to Neurodevelopmental Outcome
Ment L, Scott D, Lange R, Ehrenkranz R, Duncan C, Warshaw J. Postpartum Perfusion of the Preterm Brain: Relationship to Neurodevelopmental Outcome. Child's Brain 1983, 10: 266-272. PMID: 6884128, DOI: 10.1159/000120122.Peer-Reviewed Original ResearchConceptsCerebral blood flow measurementsCBF valuesHigher CBF valuesComputerized tomography scanDays of lifeBlood flow measurementsIntraventricular hemorrhageNeurodevelopmental outcomesPreterm brainPreterm infantsFavorable outcomeTomography scanMental indexDevelopmental assessmentLeft hemisphereOutcomesHemorrhageInfantsPerfusion
1982
Local cerebral glucose utilization in the beagle puppy model of intraventricular hemorrhage.
Ment L, Stewart W, Duncan C. Local cerebral glucose utilization in the beagle puppy model of intraventricular hemorrhage. Journal Of Neurosurgery 1982, 57: 384-9. PMID: 7097335, DOI: 10.3171/jns.1982.57.3.0384.Peer-Reviewed Original ResearchConceptsLocal cerebral glucose utilizationCerebral glucose utilizationBeagle puppy modelIntraventricular hemorrhagePuppy modelGlucose utilizationCerebral blood flowAdult animal studiesWhite matter differentiationControl pupsBlood flowAnimal studiesNeuropathological conditionsBrain regionsHemorrhageMatter differentiationUptakePups
1981
Alterations in cerebral blood flow in preterm infants with intraventricular hemorrhage.
Ment L, Ehrenkranz R, Lange R, Rothstein P, Duncan C. Alterations in cerebral blood flow in preterm infants with intraventricular hemorrhage. Pediatrics 1981, 68: 763-9. PMID: 7322711, DOI: 10.1542/peds.68.6.763.Peer-Reviewed Original ResearchConceptsWeeks postconceptual ageGerminal matrix hemorrhageIntraventricular hemorrhageIVH groupPreterm infantsPostconceptual ageCerebral blood flow determinationsCerebral blood flowComputed tomography scanGroups of infantsBlood flow determinationsNonhemorrhage patientsIVH patientsAutopsy findingsTomography scanCT scanBlood flowHemorrhageHemispheric ratioInfantsMean differencePatientsLower mean valuesInterhemispheric ratioAge