2000
Outcome of Children in the Indomethacin Intraventricular Hemorrhage Prevention Trial
Ment L, Vohr B, Allan W, Westerveld M, Sparrow S, Schneider K, Katz K, Duncan C, Makuch R. Outcome of Children in the Indomethacin Intraventricular Hemorrhage Prevention Trial. Pediatrics 2000, 105: 485-491. PMID: 10699097, DOI: 10.1542/peds.105.3.485.Peer-Reviewed Original ResearchMeSH KeywordsAnti-Inflammatory Agents, Non-SteroidalBrain Damage, ChronicCerebral HemorrhageCerebral VentriclesChild, PreschoolDose-Response Relationship, DrugFemaleFollow-Up StudiesHumansIndomethacinInfantInfant, NewbornInfant, Premature, DiseasesMaleNeurologic ExaminationNeuropsychological TestsPregnancyConceptsLow-dose indomethacinIntraventricular hemorrhagePlacebo childrenIndomethacin therapyPreterm infantsEarly administrationNeurologic examinationPrevention trialsLow birth weight preterm infantsStudy childrenBirth weight preterm infantsSeverity of IVHLow birth weight survivorsMean gestational ageWeight preterm infantsAdverse neurodevelopmental outcomesOutcome of childrenStandard neurologic examinationYears of ageNeurodevelopmental handicapPreterm neonatesNeurodevelopmental examinationNeurodevelopmental outcomesCerebral palsyGestational age
1994
Low-dose indomethacin therapy and extension of intraventricular hemorrhage: A multicenter randomized trial
Ment L, Oh W, Ehrenkranz R, Phillip A, Vohr B, Allan W, Makuch R, Taylor K, Schneider K, Katz K, Scott D, Duncan C. Low-dose indomethacin therapy and extension of intraventricular hemorrhage: A multicenter randomized trial. The Journal Of Pediatrics 1994, 124: 951-955. PMID: 8201485, DOI: 10.1016/s0022-3476(05)83191-9.Peer-Reviewed Original ResearchConceptsLow-grade intraventricular hemorrhageIntraventricular hemorrhageAdverse eventsBirth weightLow birth weight infantsDistribution of hemorrhageGrade intraventricular hemorrhageBirth weight infantsPlacebo-controlled trialPercentage of infantsPatent ductus arteriosusGm birth weightHours of ageIndomethacin therapyWeight infantsApgar scoreParenchymal involvementSaline placeboDuctus arteriosusGestational ageIntracranial hemorrhagePostnatal hoursCascade of eventsPatent ductusCranial sonograms