2009
Loss of Carbamoyl Phosphate Synthetase I in Small-Intestinal Adenocarcinoma
Cardona D, Zhang X, Liu C. Loss of Carbamoyl Phosphate Synthetase I in Small-Intestinal Adenocarcinoma. American Journal Of Clinical Pathology 2009, 132: 877-882. PMID: 19926579, DOI: 10.1309/ajcp74xgrfwtflju.Peer-Reviewed Original ResearchConceptsCases of duodenitisWestern blot analysisHep Par 1 antibodyHep Par 1 expressionHep Par 1Low-grade dysplasiaPAR-1 expressionBlot analysisExpression of CPS1CPS1 expressionIntestinal adenocarcinomaImmunohistochemical findingsInvasive adenocarcinomaInvasive tumorsMalignant tumorsAntigen expressionNormal mucosaControl groupAdenocarcinomaPAR-1AdenomasSmall intestine enterocytes
2007
The antigen for Hep Par 1 antibody is the urea cycle enzyme carbamoyl phosphate synthetase 1
Butler S, Dong H, Cardona D, Jia M, Zheng R, Zhu H, Crawford J, Liu C. The antigen for Hep Par 1 antibody is the urea cycle enzyme carbamoyl phosphate synthetase 1. Laboratory Investigation 2007, 88: 78-88. PMID: 18026163, DOI: 10.1038/labinvest.3700699.Peer-Reviewed Original ResearchMeSH KeywordsAntibodies, MonoclonalAntigensBase SequenceBlotting, WesternCarbamoyl-Phosphate Synthase (Ammonia)Chromatography, LiquidDNA PrimersFemaleHumansImmunoprecipitationLiver NeoplasmsMaleReverse Transcriptase Polymerase Chain ReactionSpectrometry, Mass, Electrospray IonizationTandem Mass SpectrometryConceptsHep Par 1 antibodyHep Par 1Carbamoyl phosphate synthetase 1Carcinoma cell linesHepatocellular carcinoma cell linesHuman hepatocellular carcinoma cell linePAR-1Cell linesHepatocyte paraffin 1Small intestinal tissueSurgical pathology practiceCPS1 expressionMurine monoclonal antibodiesHepatoid tumorsHuman liver tissueHepatocellular originIntestinal tissueRate-limiting enzymeLiver carcinogenesisSynthetase 1Liver tissuePathology practiceAntigenLiver pathobiologyMonoclonal antibodies