2016
The Prognostic and Predictive Role of Epidermal Growth Factor Receptor in Surgical Resected Pancreatic Cancer
Guo M, Luo G, Liu C, Cheng H, Lu Y, Jin K, Liu Z, Long J, Liu L, Xu J, Huang D, Ni Q, Yu X. The Prognostic and Predictive Role of Epidermal Growth Factor Receptor in Surgical Resected Pancreatic Cancer. International Journal Of Molecular Sciences 2016, 17: 1090. PMID: 27399694, PMCID: PMC4964466, DOI: 10.3390/ijms17071090.Peer-Reviewed Original ResearchMeSH KeywordsAgedAntigens, Tumor-Associated, CarbohydrateCarcinoma, Pancreatic DuctalChemotherapy, AdjuvantDisease-Free SurvivalErbB ReceptorsFemaleHumansImmunohistochemistryKaplan-Meier EstimateLymphatic MetastasisMaleMiddle AgedMultivariate AnalysisPancreatic NeoplasmsPredictive Value of TestsPrognosisProportional Hazards ModelsRetrospective StudiesConceptsAdjuvant chemotherapyPostoperative survivalEGFR statusOverall survivalSurvival benefitEGFR expressionPancreatic cancerProlonged median overall survivalResected pancreatic cancer patientsAssociated with improved survivalSurgically resected pancreatic cancerMedian overall survivalResectable pancreatic cancerSignificant survival benefitEpidermal growth factor receptorKaplan-Meier analysisPancreatic cancer patientsPancreatic cancer treatmentStudies of EGFRGrowth factor receptorResectable PDACAdjuvant therapyPrognostic significanceImproved survivalExpression subgroups
2012
Quantitation of HER2/neu Expression in Primary Gastroesophageal Adenocarcinomas Using Conventional Light Microscopy and Quantitative Image Analysis
Jeung J, Patel R, Vila L, Wakefield D, Liu C. Quantitation of HER2/neu Expression in Primary Gastroesophageal Adenocarcinomas Using Conventional Light Microscopy and Quantitative Image Analysis. Archives Of Pathology & Laboratory Medicine 2012, 136: 610-7. PMID: 22646266, PMCID: PMC3806979, DOI: 10.5858/arpa.2011-0371-oa.Peer-Reviewed Original ResearchConceptsHER2/neu expressionHER2/neu overexpressionGE tumorsBreast cancerNeu expressionNeu overexpressionIHC expressionHuman epidermal growth factor receptor 2Epidermal growth factor receptor 2Anti-HER2/neu antibodyGE junction tumorsGrowth factor receptor 2IHC interpretationIHC scoring systemHER2/neuFactor receptor 2Conventional light microscopyGastroesophageal adenocarcinomaOverall survivalClinicopathologic featuresIHC 3Resection specimensIHC 2Tumor gradeBreast carcinoma