2018
Shared and distinct alterations of white matter tracts in remitted and nonremitted patients with schizophrenia
Huang J, Liu C, Hwang T, Chen Y, Hsu Y, Hwu H, Lin Y, Hsieh M, Liu C, Chien Y, Tseng W. Shared and distinct alterations of white matter tracts in remitted and nonremitted patients with schizophrenia. Human Brain Mapping 2018, 39: 2007-2019. PMID: 29377322, PMCID: PMC6866389, DOI: 10.1002/hbm.23982.Peer-Reviewed Original ResearchConceptsGeneralized fractional anisotropyGeneralized fractional anisotropy valuesAdequate antipsychotic treatmentNegative symptom scoresNonremission groupWhite matter tract integrityWhite matter integrityHealthy controlsRemission stateWhite matter tract bundlesWhite matter tractsReduced integrationAntipsychotic treatmentNonremitted patientsSchizophrenia patientsSymptomatic remissionIllness durationAnalysis of covarianceSchizophreniaDiffusion spectrum imagingTract integrityPost hoc analysisFractional anisotropyMedication dosesEducation years
2013
Facial and Prosodic Emotion Recognition Deficits Associate with Specific Clusters of Psychotic Symptoms in Schizophrenia
Tseng H, Chen S, Liu C, Howes O, Huang Y, Hsieh M, Liu C, Shan J, Lin Y, Hwu H. Facial and Prosodic Emotion Recognition Deficits Associate with Specific Clusters of Psychotic Symptoms in Schizophrenia. PLOS ONE 2013, 8: e66571. PMID: 23818944, PMCID: PMC3688591, DOI: 10.1371/journal.pone.0066571.Peer-Reviewed Original ResearchConceptsEmotion recognition abilityCluster of psychotic symptomsPsychotic symptomsEmotion recognition taskHappy emotionHealthy participantsDysfunction of brain systemsSeverity of psychotic symptomsDeficits of emotion recognitionPresentation of psychotic symptomsDSM-IV diagnostic criteriaRecognition taskPANSS total scoreSensory modalitiesEmotion recognitionRecognition abilityEvaluation of symptomatologySeverity of clinical symptomsHappy prosodyNegative symptomsPerseveration errorsWAIS-IIIDSM-IVEmotional processingBrain systemsAripiprazole for Drug-Naive or Antipsychotic-Short-Exposure Subjects With Ultra-High Risk State and First-Episode Psychosis
Liu C, Chien Y, Hsieh M, Hwang T, Hwu H, Liu C. Aripiprazole for Drug-Naive or Antipsychotic-Short-Exposure Subjects With Ultra-High Risk State and First-Episode Psychosis. Journal Of Clinical Psychopharmacology 2013, 33: 18-23. PMID: 23277261, DOI: 10.1097/jcp.0b013e31827cb017.Peer-Reviewed Original ResearchConceptsFirst-episode psychosisUltra-high riskFirst-episode psychosis patientsDrug-naiveUltra-high risk stateUltra-high-risk patientsLow-dose aripiprazoleNegative symptom scoresPositive symptom scoresFlexible dosing strategyState of psychosisTreatment responseAntipsychotic therapyDrug-naive populationSevere psychopathologyUHR patientsFirst-episodeAripiprazoleAdverse eventsSymptom scoresPsychosisRisk stateConcomitant medicationsTarget doseClinical improvement