2023
Dose-Volume Predictors of Radiation Pneumonitis After Thoracic Hypofractionated Radiation Therapy
Sasse A, Oh P, Saeed N, Yang D, Hayman T, Knowlton C, Peters G, Campbell A, Laird J, Housri N, Park H. Dose-Volume Predictors of Radiation Pneumonitis After Thoracic Hypofractionated Radiation Therapy. Practical Radiation Oncology 2023, 14: e97-e104. PMID: 37984711, DOI: 10.1016/j.prro.2023.11.006.Peer-Reviewed Original ResearchMean lung doseHypofractionated radiation therapyRisk of gradeRadiation pneumonitisLung V20Lung V5Dose-volume predictorsDosimetric risk factorsLogistic regression analysisGrade 5 casesSingle healthcare systemPrimary endpointDose regimensMultivariable analysisLung doseThoracic tumorsDosimetric variablesRisk factorsPneumonitisRadiation therapyCommon treatmentClinical practicePatientsSignificant associationPotential predictors
2019
Standard Tangential Radiation Fields Do Not Provide Incidental Coverage to the Internal Mammary Nodes
Loganadane G, Kassick M, Kann BH, Young MR, Knowlton CA, Evans SB, Higgins SA, Belkacemi Y, Potenziani M, Saltmarsh N, Wilson LD, Moran MS. Standard Tangential Radiation Fields Do Not Provide Incidental Coverage to the Internal Mammary Nodes. Practical Radiation Oncology 2019, 10: 21-28. PMID: 31394256, DOI: 10.1016/j.prro.2019.07.014.Peer-Reviewed Original ResearchConceptsInternal mammary nodesClinical target volumePlanning target volumeIMN chainMean doseTangential radiation fieldsTarget volumePostmastectomy radiationMammary nodesRadiation therapyAdjuvant whole breast radiation therapyWhole breast radiation therapyRegional nodal radiationConformal radiation therapyNodal radiationPrimary endpointMedian doseTherapeutic coverageStudy cohortTherapeutic dosesBreast cancerIncidental doseAxillary fieldKruskal-Wallis testSupraclavicular field
2011
Radiotherapy in the treament of gastrointestinal stromal tumors
Knowlton C, Brady L, Heintzelman R. Radiotherapy in the treament of gastrointestinal stromal tumors. Rare Tumors 2011, 3: 35. PMID: 22355490, PMCID: PMC3282440, DOI: 10.4081/rt.2011.e35.Peer-Reviewed Original ResearchGastrointestinal stromal tumorsTreatment of gastrointestinal stromal tumorsStromal tumorsCase of metastatic gastrointestinal stromal tumourLong-term local controlMetastatic gastrointestinal stromal tumorsTreated with local radiotherapyUnresectable gastrointestinal stromal tumorsTyrosine kinase inhibitorsRate of metastasisStandard of careLocal radiotherapyResectable diseaseRadiosensitive tumorsRadiation therapySurgical resectionMesenchymal tumorsImatinib mesylatePalliative settingRadiotherapyKinase inhibitorsLocal controlTumorPatientsGastrointestinal tract