2024
Saturday, July 13, 202411:30 AM - 12:30 PMGSOR01 Presentation Time: 11:30 AM A Prospective Clinical Trial Assessing Comfort of Brachytherapy with a Novel Tapered Vaginal Applicator
Mahal A, Yu J, Mahal R, Tien C, Adefres B, Damast S. Saturday, July 13, 202411:30 AM - 12:30 PMGSOR01 Presentation Time: 11:30 AM A Prospective Clinical Trial Assessing Comfort of Brachytherapy with a Novel Tapered Vaginal Applicator. Brachytherapy 2024, 23: s72-s73. DOI: 10.1016/j.brachy.2024.08.099.Peer-Reviewed Original ResearchVisual-analogue-scaleVaginal brachytherapyVaginal stretchingVaginal applicationEndometrial cancerAssociated with less painIr-192 seedsDose fall-offClinically significant responseProspective clinical trialPatient-centered evaluationVaginal introitusProspective trialsDose distributionSurface doseVaginal mucosaIr-192Less painNarrow introitusPaired t-testEC patientsConsenting patientsClinical trialsIntroitusPatients
2023
PO83 Utilization of a Virtual Clinical Trial to Characterize Sensitivity of the Linear-Quadratic Model
Tien C, Draeger E, Guan F, Carlson D, Chen Z. PO83 Utilization of a Virtual Clinical Trial to Characterize Sensitivity of the Linear-Quadratic Model. Brachytherapy 2023, 22: s110. DOI: 10.1016/j.brachy.2023.06.184.Peer-Reviewed Original ResearchTumor control probabilityClinical trialsLinear-quadratic modelNumber of patientsPatient cohort sizeTCP curvesRadiobiological parametersVirtual clinical trialsGy-1Cohort sizeRange of dosesPatient outcomesReference cohortPatientsHeterogeneous cohortVirtual patientsNew trialsRadiobiological parameter valuesClonogenic populationPatient ordersControl probabilityGyInput model parametersTrialsCohortPreliminary dosimetric comparison between fixed and rotating source stereotactic radiosurgery systems
Draeger E, Chen Z, Hansen J, Chiang V, Tien C. Preliminary dosimetric comparison between fixed and rotating source stereotactic radiosurgery systems. Journal Of Applied Clinical Medical Physics 2023, 24: e13907. PMID: 36660774, PMCID: PMC10161057, DOI: 10.1002/acm2.13907.Peer-Reviewed Original ResearchConceptsConformity indexRadiation Therapy Oncology Group conformity indexGK plansSuperior conformity indexNon-metastatic casesPaddick conformity indexDosimetric plan qualityGK patientsBrain metastasesRadiosurgery systemTrigeminal neuralgiaPrescription dosesGamma Knife systemMetastatic casesArteriovenous malformationsPituitary adenomasConformality indexLarge cohortDosimetric comparisonStereotactic radiosurgery systemGK IconPatientsCohortTreatment timeDosimetric results
2022
Single application hybrid interstitial brachytherapy for cervical cancer: an institutional approach during the COVID-19 pandemic
Damast S, Tien CJ, Young M, Altwerger G, Ratner E. Single application hybrid interstitial brachytherapy for cervical cancer: an institutional approach during the COVID-19 pandemic. Journal Of Contemporary Brachytherapy 2022, 14: 66-71. PMID: 35233237, PMCID: PMC8867238, DOI: 10.5114/jcb.2022.113058.Peer-Reviewed Original ResearchOverall treatment timeHR-CTV DCervical cancerMucosal toxicityMedian high-risk clinical target volumeHigh-risk clinical target volumeCOVID-19 pandemicLocal control outcomesPre-COVID cohortClinical target volumeMagnetic resonance imagingGastrointestinal eventsRetrospective reviewCC patientsEarly outcomesCOVID groupMedian numberInpatient resourcesInterstitial brachytherapyGrade 2Local controlResonance imagingSeparate weeksTarget volumePatients
2013
SU‐E‐J‐24: Imaging Dose Dependence On Fractionation Scheme and Tracking Method in CyberKnife Robotic Radiosurgery
Tien C, Dieterich S, Lee S, Curran B, Sternick E. SU‐E‐J‐24: Imaging Dose Dependence On Fractionation Scheme and Tracking Method in CyberKnife Robotic Radiosurgery. Medical Physics 2013, 40: 154-154. DOI: 10.1118/1.4814236.Peer-Reviewed Original ResearchTracking methodAmorphous silicon flat-panel detectorRobotic radiosurgeryImaging doseFractionation schemeCyberKnife robotic radiosurgeryX-ray tubeDifferent fractionation schemesFlat-panel detectorEntrance skin exposureMedian numberStereotactic radiosurgerySkin exposureOperator adjustmentRadiosurgeryDoseKVPatientsSampling intervalCyberKnifeDose differenceSU‐E‐T‐438: Dosimetric Effect of Patient Arm Position in Spinal CyberKnife Robotic Radiosurgery
Mihaylov I, Tien C, Hepel J. SU‐E‐T‐438: Dosimetric Effect of Patient Arm Position in Spinal CyberKnife Robotic Radiosurgery. Medical Physics 2013, 40: 306-306. DOI: 10.1118/1.4814872.Peer-Reviewed Original ResearchPTV coverageSpinal cordMinimum doseExtremity motionDosimetric effectsPatient's arm positionArm positionCyberKnife robotic radiosurgeryPotential dosimetric effectsPrescription dosesSpinal lesionsCyberKnife radiosurgerySpine lesionsCyberKnife treatmentSupine positionTreatment planPatientsMaximum dosePatient's armComparison plansCritical organsMean differenceRobotic radiosurgeryDoseDosimetric impact