Importance of Dietary Phosphorus for Bone Metabolism and Healthy Aging
Serna J, Bergwitz C. Importance of Dietary Phosphorus for Bone Metabolism and Healthy Aging. Nutrients 2020, 12: 3001. PMID: 33007883, PMCID: PMC7599912, DOI: 10.3390/nu12103001.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsDietary phosphorusReduced bioavailabilityHealthy agingHigh dietary phosphorusSources of dietary phosphorusReduced longevityAbundance of phosphorusBone metabolismWestern dietPhosphorusTissue calcificationMetabolic changesEndocrine regulationBioavailabilityNormal amountsTissueCurrent knowledgeAbundanceDifferent tissuesExcessive lossOsteomalaciaTargeted FGFR Blockade for the Treatment of Tumor-Induced Osteomalacia
Hartley IR, Miller CB, Papadakis GZ, Bergwitz C, Del Rivero J, Blau JE, Florenzano P, Berglund JA, Tassone J, Roszko KL, Moran S, Gafni RI, Isaacs R, Collins MT. Targeted FGFR Blockade for the Treatment of Tumor-Induced Osteomalacia. New England Journal Of Medicine 2020, 383: 1387-1389. PMID: 32905668, PMCID: PMC7561341, DOI: 10.1056/nejmc2020399.Peer-Reviewed Original ResearchMeSH KeywordsAgedChondrosarcoma, MesenchymalDisease ProgressionFatal OutcomeFibroblast Growth Factor-23Fibroblast Growth FactorsHumansMaleMolecular Targeted TherapyNeoplasms, Connective TissueOsteomalaciaParaneoplastic SyndromesPhenylurea CompoundsPositron Emission Tomography Computed TomographyPyrimidinesReceptor Protein-Tyrosine KinasesReceptor, Fibroblast Growth Factor, Type 1