2024
Lung Cancer Screening at US Hospitals for People Lacking Primary Care
DeSantis W, Ayoade O, Caturegli G, Boffa D. Lung Cancer Screening at US Hospitals for People Lacking Primary Care. JAMA Network Open 2024, 7: e2442373. PMID: 39480427, PMCID: PMC11528307, DOI: 10.1001/jamanetworkopen.2024.42373.Peer-Reviewed Original Research
2023
Telehealth Availability for Cancer Care During the COVID-19 Pandemic: Cross-Sectional Study
Marks V, Hsiang W, Nie J, Umer W, Haleem A, Galal B, Pak I, Kim D, Salazar M, Pantel H, Berger E, Boffa D, Cavallo J, Leapman M. Telehealth Availability for Cancer Care During the COVID-19 Pandemic: Cross-Sectional Study. JMIR Cancer 2023, 9: e45518. PMID: 37917149, PMCID: PMC10654905, DOI: 10.2196/45518.Peer-Reviewed Original ResearchCancer HospitalCancer careTelehealth availabilityTotal admissionsTelehealth servicesCancer typesBreast cancer careComprehensive cancer programsCross-sectional studySkin cancer careFacility-level factorsNational Cancer InstituteCOVID-19 pandemicTelehealth visitsAccountable care organizationsCommon cancerCancer programsOutpatient careCancer sitesNew patientsCancer InstitutePatientsSkin cancerHospitalMost hospitalsAlterations in Cancer Treatment During the First Year of the COVID-19 Pandemic in the US
Janczewski L, Cotler J, Merkow R, Palis B, Nelson H, Mullett T, Boffa D. Alterations in Cancer Treatment During the First Year of the COVID-19 Pandemic in the US. JAMA Network Open 2023, 6: e2340148. PMID: 37902756, PMCID: PMC10616721, DOI: 10.1001/jamanetworkopen.2023.40148.Peer-Reviewed Original ResearchConceptsNational Cancer DatabaseCancer treatmentAcademic hospitalCommunity hospitalMAIN OUTCOMECOVID-19 pandemicProportion of patientsRetrospective cohort studyAvailability of treatmentFirst yearUnderwent surgeryCohort studyMedian ageCancer surgeryMedian timeTreatment of cancerCancer careTreatment modalitiesCancer screeningCancer DatabaseMedian travel distancePatientsHospitalSurgeryCancerAssessment of a collaborative treatment model for trimodal management of esophageal cancer
Udelsman B, Ermer T, Ely S, Canavan M, Zhan P, Boffa D, Blasberg J. Assessment of a collaborative treatment model for trimodal management of esophageal cancer. Journal Of Thoracic Disease 2023, 15: 4668-4680. PMID: 37868899, PMCID: PMC10586936, DOI: 10.21037/jtd-23-346.Peer-Reviewed Original ResearchPathologic complete responseNational Cancer DatabaseGy of radiationEsophageal cancerCollaborative treatmentCollaborative treatment modelMultiagent chemotherapySingle institutionRate of pCRPatient travel burdenR0 resection rateTreatment modelTrimodality therapyTrimodality treatmentNeoadjuvant chemoradiotherapyNeoadjuvant therapyR0 resectionResection rateComplete responseMultivariable analysisTumor characteristicsCancer DatabaseMedian travel distancePatientsCollaborative CohortOverall survival in low-comorbidity patients with stage I non–small cell lung cancer who chose stereotactic body radiotherapy compared to surgery
Udelsman B, Canavan M, Zhan P, Ely S, Park H, Boffa D, Mase V. Overall survival in low-comorbidity patients with stage I non–small cell lung cancer who chose stereotactic body radiotherapy compared to surgery. Journal Of Thoracic And Cardiovascular Surgery 2023, 167: 822-833.e7. PMID: 37500052, DOI: 10.1016/j.jtcvs.2023.07.021.Peer-Reviewed Original ResearchNon-small cell lung cancerStereotactic body radiotherapyStage I non-small cell lung cancerLow-comorbidity patientsCell lung cancerOverall survivalSurgical managementLung cancerSurgical resectionBody radiotherapyClinical stage I non-small cell lung cancerEarly-stage non-small cell lung cancerPropensity score-matched cohortPropensity score-matched patientsPropensity score-matched analysisEarly-stage lung cancerLong-term OSNational Cancer DatabaseProportion of patientsCancer DatabasePatientsSBRT patientsSurgeryCancerMortalityEffect of pandemic-related reductions in cancer care delivery on different US health systems.
Janczewski L, Cotler J, Merkow R, Palis B, Nelson H, Mullett T, Boffa D. Effect of pandemic-related reductions in cancer care delivery on different US health systems. Journal Of Clinical Oncology 2023, 41: e18811-e18811. DOI: 10.1200/jco.2023.41.16_suppl.e18811.Peer-Reviewed Original ResearchNational Cancer DatabaseHospital typeAcademic hospitalUS healthcare systemTreatment modalitiesCommunity hospitalTreatment utilizationCancer treatmentCOVID-19 pandemicCancer care deliveryTypes of malignanciesHealthcare systemDifferent hospital typesEvaluation of cancerChi-squared testUS health systemFirst yearUnderwent surgerySurgical patientsCancer careCancer DatabaseSurgical carePatientsTreatment declineDescriptive univariate statistics
2022
Utilization and Outcomes of Radiation in Stage IV Esophageal Cancer
Zhan P, Canavan M, Ermer T, Pichert M, Li A, Maduka R, Kaminski M, Johung K, Boffa D. Utilization and Outcomes of Radiation in Stage IV Esophageal Cancer. JTO Clinical And Research Reports 2022, 3: 100429. PMID: 36483656, PMCID: PMC9722471, DOI: 10.1016/j.jtocrr.2022.100429.Peer-Reviewed Original ResearchStage IV esophageal cancerNational Cancer DatabaseEsophageal cancerCancer DatabaseRadiation doseSurvival advantageMedian total radiation dosePropensity score-matched pairsOutcome of radiationRetrospective cohort studyKaplan-Meier analysisTotal radiation doseAppropriate radiation dosePalliative regimensCohort studyMedian ageRadiation administrationSurvival associationsBetter survivalPatientsLocal controlCancerDosePalliationFurther studiesCancer of the Lung
Morgensztern D, Boffa D, Chen A, Dhanasopon A, Goldberg S, Decker R, Devarakonda S, Ko J, Soto L, Waqar S, Wistuba I, Herbst R. Cancer of the Lung. 2022, 1-29. DOI: 10.1002/9781119000822.hfcm085.pub2.Peer-Reviewed Original ResearchEvaluating information loss in the National Cancer Database from cases lost to follow‐up
Cotler JH, Nogueira L, McCabe R, Nelson H, Brajcich BC, Boffa DJ, Lum SS, Harris JB, Hawhee V, Mullett TW, Bilimoria KY, Palis BE. Evaluating information loss in the National Cancer Database from cases lost to follow‐up. Journal Of Surgical Oncology 2022, 126: 1123-1132. PMID: 36029288, DOI: 10.1002/jso.26977.Peer-Reviewed Original ResearchConceptsNational Cancer DatabaseCancer casesPediatric casesAdult casesCancer DatabaseRectal cancer casesLung cancer casesMean survival timeBreast cancer casesHazard ratioCancer RegistryYears postdiagnosisSurvival outcomesLymphoma casesSurvival timeLeukemia casesSurvival analysisResource burdenFollowTotalMinimal differencesYearsAnnual increasePostdiagnosisPatientsAssociation of Insurance Status and Extent of Organ Involvement With Survival Among Patients With Stage IV Cancer
Zhan PL, Canavan ME, Ermer T, Pichert MD, Li AX, Maduka RC, Boffa DJ. Association of Insurance Status and Extent of Organ Involvement With Survival Among Patients With Stage IV Cancer. JAMA Network Open 2022, 5: e2217581. PMID: 35713907, PMCID: PMC9206181, DOI: 10.1001/jamanetworkopen.2022.17581.Peer-Reviewed Original ResearchRevisiting Indications for Brain Imaging During the Clinical Staging Evaluation of Lung Cancer
Pichert MD, Canavan ME, Maduka RC, Li AX, Ermer T, Zhan PL, Kaminski M, Udelsman BV, Blasberg JD, Mase VJ, Dhanasopon AP, Boffa DJ. Revisiting Indications for Brain Imaging During the Clinical Staging Evaluation of Lung Cancer. JTO Clinical And Research Reports 2022, 3: 100318. PMID: 35540711, PMCID: PMC9079298, DOI: 10.1016/j.jtocrr.2022.100318.Peer-Reviewed Original ResearchPrevalence of brainBrain metastasesSummary stageBrain imagingN classificationIsolated brain metastasesNode-negative NSCLCRoutine brain imagingStage II NSCLCStage IV NSCLCClinical stage INational Cancer DatabaseEarly-stage NSCLCStage IAStage IIIAStage NSCLCStaging evaluationClinical stageLung cancerCancer DatabaseN stageNSCLCPatientsStage IMetastasisNonadherence to Multimodality Cancer Treatment Guidelines in the United States
Tchelebi LT, Shen B, Wang M, Potters L, Herman J, Boffa D, Segel JE, Park HS, Zaorsky NG. Nonadherence to Multimodality Cancer Treatment Guidelines in the United States. Advances In Radiation Oncology 2022, 7: 100938. PMID: 35469182, PMCID: PMC9034283, DOI: 10.1016/j.adro.2022.100938.Peer-Reviewed Original ResearchGuideline-concordant treatmentAnal cancerMultimodality treatmentRectal cancerCervical cancerLung cancerAdvanced non-small cell lung cancerNasopharynx cancerNon-small cell lung cancerNonmetastatic anal cancerNational Cancer DatabasePercent of patientsAdvanced cervical cancerCancer treatment guidelinesCell lung cancerMultivariable logistic regressionPrimary tumor siteLow-volume facilitiesTreatment guidelinesComorbid conditionsCancer DatabaseOdds ratioNational guidelinesPatientsConfounding variablesAccess to High-Volume Hospitals for High-Risk Cancer Surgery for Racial and Ethnic Minoritized Groups
Salazar MC, Canavan ME, Holaday LW, Billingsley KG, Ross J, Boffa DJ, Gross CP. Access to High-Volume Hospitals for High-Risk Cancer Surgery for Racial and Ethnic Minoritized Groups. JNCI Cancer Spectrum 2022, 6: pkac024. PMID: 35603855, PMCID: PMC8997114, DOI: 10.1093/jncics/pkac024.Peer-Reviewed Original ResearchConceptsHigh-risk cancer surgeryHigh-volume hospitalsCancer surgeryHispanic patientsNational Cancer DatabaseNon-Hispanic patientsNon-black patientsLung resectionBlack patientsCancer DatabaseBetter outcomesPatientsSurgeryHospitalPancreatectomyLow probabilityInequitable accessEsophagectomyProctectomyResection
2021
Twenty-Five Years of Cancer Follow-Up; Is the Data Worth the Effort?
Brajcich BC, Palis BE, McCabe R, Nogueira L, Boffa DJ, Lum SS, Harris JB, Hawhee V, Mullett TW, Bilimoria KY, Nelson H. Twenty-Five Years of Cancer Follow-Up; Is the Data Worth the Effort? Annals Of Surgical Oncology 2021, 29: 828-836. PMID: 34689251, DOI: 10.1245/s10434-021-10668-w.Peer-Reviewed Original ResearchChange in facility-level share of Medicaid patients with cancer following implementation of the affordable care act.
Buck M, Demkowicz P, Nie J, Marks V, Salazar M, Kenney P, Boffa D, Leapman M. Change in facility-level share of Medicaid patients with cancer following implementation of the affordable care act. Journal Of Clinical Oncology 2021, 39: e18543-e18543. DOI: 10.1200/jco.2021.39.15_suppl.e18543.Peer-Reviewed Original ResearchProportion of MedicaidAffordable Care ActMedicaid patientsMedicaid expansionFacility-level changesFacility-level policiesNational Cancer DatabasePrimary study endpointProportion of patientsInsurance coverageMultivariable logistic regressionExpansion statesCare ActFacility-level factorsMedicaid expansion statesNon-expansion statesAdult patientsStudy endpointAdjusted differenceCancer DatabaseMedicaid populationEligible facilitiesPatientsCancerLogistic regressionThe Survival Advantage of Lobectomy over Wedge Resection Lessens as Health-Related Life Expectancy Decreases
Salazar MC, Canavan ME, Walters SL, Chilakamarry S, Ermer T, Blasberg JD, Yu JB, Gross CP, Boffa DJ. The Survival Advantage of Lobectomy over Wedge Resection Lessens as Health-Related Life Expectancy Decreases. JTO Clinical And Research Reports 2021, 2: 100143. PMID: 34590002, PMCID: PMC8474228, DOI: 10.1016/j.jtocrr.2021.100143.Peer-Reviewed Original ResearchStage I NSCLCWedge resectionSurveillance EpidemiologyMortality riskHigh riskSurvival advantageLife expectancyNational Cancer Institute's Surveillance EpidemiologyEnd Results-MedicareTreatment-naive patientsEarly-stage NSCLCRetrospective cohort studySuperior local controlShort life expectancyLife expectancy decreasesPerioperative complicationsCohort studyComorbid conditionsLung parenchymaLobectomyCox modelReasonable optionPatientsNSCLCLocal controlChemoradiation as a nonsurgical treatment option for early-stage esophageal cancers: a retrospective cohort study
Pathak R, Canavan ME, Walters S, Salazar MC, Boffa DJ. Chemoradiation as a nonsurgical treatment option for early-stage esophageal cancers: a retrospective cohort study. Journal Of Thoracic Disease 2021, 13: 140-148. PMID: 33569194, PMCID: PMC7867841, DOI: 10.21037/jtd-20-1187.Peer-Reviewed Original ResearchEarly-stage esophageal cancerEsophageal cancerOverall survivalDefinitive non-surgical treatmentComorbidity-free patientsCT1/T2National Cancer DatabaseRetrospective cohort studyNon-surgical treatmentSubset of patientsGoals of careKaplan-Meier curvesNonsurgical treatment optionsKaplan-Meier estimatesInoperable patientsCohort studyNonsurgical approachCure rateTreatment optionsCancer patientsEndoscopic excisionCancer DatabaseTumor removalChemoradiationPatients
2020
Where the Other Half Dies: Analysis of Mortalities Occurring More Than 30 Days After Complex Cancer Surgery
Resio BJ, Gonsalves L, Canavan M, Mueller L, Phillips C, Sathe T, Swett K, Boffa DJ. Where the Other Half Dies: Analysis of Mortalities Occurring More Than 30 Days After Complex Cancer Surgery. Annals Of Surgical Oncology 2020, 28: 1278-1286. PMID: 32885398, DOI: 10.1245/s10434-020-09080-7.Peer-Reviewed Original ResearchConceptsComplex cancer surgeryCause of deathCancer surgeryLate mortalityNursing facilitiesTumor registry databaseLate postoperative periodDay of surgeryLocation of deathAnalysis of mortalityCircumstances of deathIndex admissionPulmonary causesCardiac causesOperative mortalityFatal complicationPostoperative periodThromboembolic diseaseNonmetastatic cancerRegistry databaseDeath documentationSurgical safetySurgeryPatientsMortalityNavigating by Stars: Using CMS Star Ratings to Choose Hospitals for Complex Cancer Surgery
Papageorge MV, Resio BJ, Monsalve AF, Canavan M, Pathak R, Mase VJ, Dhanasopon AP, Hoag JR, Blasberg JD, Boffa DJ. Navigating by Stars: Using CMS Star Ratings to Choose Hospitals for Complex Cancer Surgery. JNCI Cancer Spectrum 2020, 4: pkaa059-. PMID: 33134834, PMCID: PMC7583163, DOI: 10.1093/jncics/pkaa059.Peer-Reviewed Original ResearchComplex cancer surgeryCMS star ratingsCancer surgerySafe hospitalReassignment of patientsMedicare Provider AnalysisYears of ageHospital mortalitySurgical outcomesSurgical careMedicare beneficiariesMortality ratePatientsSurgeryHospitalHospital qualityReview filesMedicaid ServicesMortalityOnly modest impactOutcomesStar ratingsModest impactYearsAssociation of hospital type and patient volume growth with timely cancer treatment.
Frosch Z, Illenberger N, Mitra N, Boffa D, Facktor M, Nelson H, Bekelman J, Shulman L, Takvorian S. Association of hospital type and patient volume growth with timely cancer treatment. Journal Of Clinical Oncology 2020, 38: 2022-2022. DOI: 10.1200/jco.2020.38.15_suppl.2022.Peer-Reviewed Original ResearchNational Cancer InstituteHospital typeAcademic hospitalPatient volumeCancer treatmentNational Cancer DatabaseRegional referral centerTime interactionComplex cancer careTimely cancer treatmentReferral centerPrimary outcomeInitial treatmentCancer careCancer DatabasePatient outcomesCommunity hospitalTimely treatmentNew diagnosisCancer InstituteLinear mixed effects modelsHospitalPatientsSuperior outcomesStudy period