Neuroanatomical changes in a mouse model of early life neglect
Duque A, Coman D, Carlyle BC, Bordner KA, George ED, Papademetris X, Hyder F, Simen AA. Neuroanatomical changes in a mouse model of early life neglect. Brain Structure And Function 2011, 217: 459-472. PMID: 21984312, PMCID: PMC3664301, DOI: 10.1007/s00429-011-0350-9.Peer-Reviewed Original ResearchConceptsMouse modelNeuroanatomical changesEarly life neglectNovel mouse modelNovel animal modelWhite matter disorganizationMaternal separationCortical thicknessAdult miceAnimal modelsBehavioral abnormalitiesInter-hemispheric asymmetrySmall brain sizeSubcortical structuresPharmacological experimentationProtein expressionLeft hemisphereEarly weaningHuman survivorsAbnormalitiesCurrent knowledgeBrain sizeConcomitant changesAtrophyRole of Ongoing, Intrinsic Activity of Neuronal Populations for Quantitative Neuroimaging of Functional Magnetic Resonance Imaging–Based Networks
Hyder F, Herman P, Sanganahalli BG, Coman D, Blumenfeld H, Rothman DL. Role of Ongoing, Intrinsic Activity of Neuronal Populations for Quantitative Neuroimaging of Functional Magnetic Resonance Imaging–Based Networks. Brain Connectivity 2011, 1: 185-193. PMID: 22433047, PMCID: PMC3621320, DOI: 10.1089/brain.2011.0032.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingEnergy/activityMagnetic resonance imagingBOLD signalNeuronal activityQuantitative neuroimagingNeuronal populationsResonance imagingBaseline BOLD signalsTotal neuronal activityBlood oxygenation level-dependent (BOLD) signalLevel-dependent signalResting-state fMRI experimentsAnimal modelsFMRI experimentMagnetic resonance spectroscopy measurementsBrain networksBaselineNeuroimagingPrimary objectiveImagingIntrinsic activityActivityPopulation