2006
Anatomical mapping of human herpesvirus reservoirs of infection
Chen T, Hudnall SD. Anatomical mapping of human herpesvirus reservoirs of infection. Modern Pathology 2006, 19: 726-737. PMID: 16528368, DOI: 10.1038/modpathol.3800584.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAnal CanalAutopsyCytomegalovirusDNA, ViralFemaleHerpesviridaeHerpesviridae InfectionsHerpesvirus 1, HumanHerpesvirus 2, HumanHerpesvirus 3, HumanHerpesvirus 4, HumanHerpesvirus 6, HumanHerpesvirus 7, HumanHerpesvirus 8, HumanHumansIntestinesMaleMiddle AgedNasal MucosaNervous SystemThyroid GlandConceptsHHV-6Whole blood specimensHSV-1Lymph nodesHHV-7Nasal mucosaAnatomic sitesHuman herpesvirusesHIV-AIDSActive herpesvirus infectionHSV-1 positivitySalivary glandsMajor anatomic sitesMiddle-aged malesTime of deathCardiac arrestHHV-8Adrenal glandElderly malesPrimary infectionHSV-2Urinary bladderHerpesvirus infectionAnatomical mappingBone marrow
2004
Species identification of all eight human herpesviruses with a single nested PCR assay
Hudnall SD, Chen T, Tyring SK. Species identification of all eight human herpesviruses with a single nested PCR assay. Journal Of Virological Methods 2004, 116: 19-26. PMID: 14715303, DOI: 10.1016/j.jviromet.2003.10.005.Peer-Reviewed Original ResearchMeSH KeywordsCytomegalovirusDNA PrimersDNA-Directed DNA PolymeraseElectrophoretic Mobility Shift AssayHerpesviridaeHerpesvirus 1, HumanHerpesvirus 2, HumanHerpesvirus 3, HumanHerpesvirus 4, HumanHerpesvirus 6, HumanHerpesvirus 7, HumanHerpesvirus 8, HumanHeteroduplex AnalysisHumansNucleic Acid HybridizationPolymerase Chain ReactionConceptsHuman herpesvirusesPolymerase chain reactionHHV-6 subtypesClinical materialSignificant morbidityViral culturePrimary infectionLatent persistenceMultiple herpesvirusesChemiluminescent dot blot hybridizationChain reactionHeteroduplex mobilityHuman hostHerpesvirus detectionDot blot hybridizationHerpesvirusHerpesvirus DNA polymerase gene
2003
Human herpesvirus 8 seroprevalence and viral load in healthy adult blood donors
Hudnall SD, Chen T, Rady P, Tyring S, Allison P. Human herpesvirus 8 seroprevalence and viral load in healthy adult blood donors. Transfusion 2003, 43: 85-90. PMID: 12519435, DOI: 10.1046/j.1537-2995.2003.00272.x.Peer-Reviewed Original ResearchConceptsHHV-8 seroprevalenceBlood donorsDonor bloodPrimary effusion B-cell lymphomaABO blood group BHigh HHV-8 seroprevalenceHuman herpesvirus 8 seroprevalenceLatent HHV-8 antigensHealthy adult blood donorsBlood donor unitsBuffy coat DNAHHV-8 antigensHHV-8 ORF26HHV-8 viremiaSensitive indirect immunofluorescenceGeometric mean titersAdult blood donorsHHV-8 antibodiesHHV-8 DNABlood-borne virusesHuman herpesvirus 8B-cell lymphomaBlood group BDonor blood samplesHuman tumor virus
2000
Differential Expression of the HHV-8 vGCR Cellular Homolog Gene in AIDS-Associated and Classic Kaposi's Sarcoma: Potential Role of HIV-1 Tat
Yen-Moore A, Hudnall S, Rady P, Wagner R, Moore T, Memar O, Hughes T, Tyring S. Differential Expression of the HHV-8 vGCR Cellular Homolog Gene in AIDS-Associated and Classic Kaposi's Sarcoma: Potential Role of HIV-1 Tat. Virology 2000, 267: 247-251. PMID: 10662620, DOI: 10.1006/viro.1999.0125.Peer-Reviewed Original ResearchMeSH KeywordsAcquired Immunodeficiency SyndromeCyclin DCyclinsGene Expression Regulation, ViralGene Products, tatHerpesvirus 8, HumanHIV-1HumansLeukocytes, MononuclearOncogenesReceptors, Cell SurfaceReverse Transcriptase Polymerase Chain ReactionRNASarcoma, KaposiTat Gene Products, Human Immunodeficiency VirusTetradecanoylphorbol AcetateTumor Cells, CulturedViral ProteinsConceptsHIV-1 TatClassic Kaposi's sarcomaKaposi's sarcomaPeripheral blood mononuclear cellsAIDS-KS tissueBlood mononuclear cellsReverse transcriptase-polymerase chain reactionHuman herpesvirus 8Positive lymphoma cellsHHV-8 genesInterferon regulatory factor 1AIDS-associatedInflammatory proteinMononuclear cellsPolymerase chain reactionInterleukin-6Herpesvirus 8Regulatory factor 1SarcomaAngiogenic effectsLymphoma cellsBcl-2Factor 1Chain reactionPotential role
1998
Serologic and Molecular Evidence of Human Herpesvirus 8 Activation in Renal Transplant Recipients
Hudnall S, Rady P, Tyring S, Fish J. Serologic and Molecular Evidence of Human Herpesvirus 8 Activation in Renal Transplant Recipients. The Journal Of Infectious Diseases 1998, 178: 1791-1794. PMID: 9815236, DOI: 10.1086/314482.Peer-Reviewed Original ResearchConceptsRenal transplant patientsGeometric mean titersHealthy adultsTransplant patientsPolymerase chain reactionRenal transplant populationRenal transplant recipientsHIV-positive adultsHuman immunodeficiency virusViral DNATransplant recipientsTransplant groupTransplant populationMean titersImmunodeficiency virusImmunocompromised populationsSerum antibodiesKaposi's sarcomaPositive adultsSerologic resultsIndirect immunofluorescenceWhole bloodChain reactionAdultsPatientsDetection of human herpesvirus-8 DNA in Kaposi’s sarcomas from iatrogenically immunosuppressed patients
Rady P, Hodak E, Yen A, Memar O, Trattner A, Feinmesser M, David M, Hudnall S, Tyring S. Detection of human herpesvirus-8 DNA in Kaposi’s sarcomas from iatrogenically immunosuppressed patients. Journal Of The American Academy Of Dermatology 1998, 38: 429-437. PMID: 9520025, DOI: 10.1016/s0190-9622(98)70501-8.Peer-Reviewed Original ResearchConceptsKaposi's sarcomaHHV-8Polymerase chain reactionHHV-8 DNA detectionImmunosuppressed organ transplant patientsHuman herpesvirus 8 DNAOpen reading frame 26Different primary diseasesHHV-8 sequencesIatrogenic Kaposi's sarcomaOrgan transplant patientsHHV-8 DNAClassic Kaposi's sarcomaEndemic Kaposi's sarcomaFrame 26Nontransplant patientsImmunosuppressive therapyTransplant patientsAIDS-KSPrimary diseaseBiopsy specimensHigh prevalencePatientsNew herpesvirusSarcoma