2021
Thermal ablation alone vs thermal ablation combined with transarterial chemoembolization for patients with small (<3 cm) hepatocellular carcinoma
Chai NX, Chapiro J, Petukhova A, Gross M, Kucukkaya A, Raju R, Zeevi T, Elbanan M, Lin M, Perez-Lozada JC, Schlachter T, Strazzabosco M, Pollak JS, Madoff DC. Thermal ablation alone vs thermal ablation combined with transarterial chemoembolization for patients with small (<3 cm) hepatocellular carcinoma. Clinical Imaging 2021, 76: 123-129. PMID: 33592550, PMCID: PMC8217099, DOI: 10.1016/j.clinimag.2021.01.043.Peer-Reviewed Original ResearchConceptsOverall survivalTransarterial chemoembolizationHepatocellular carcinomaThermal ablationTA groupEarly-stage hepatocellular carcinomaMedian overall survivalTherapy-naïve patientsKaplan-Meier analysisMaximum tumor diameterStage hepatocellular carcinomaLog-rank testDrug-eluting beadsSmall hepatocellular carcinomaTerms of TTPHIPAA-compliant IRBSignificant differencesLipiodol-TACELocoregional therapyBCLC stageComplication rateTreatment cohortsTumor diameterAFP levelsPatient group
2017
Update on Embolization Therapies for Hepatocellular Carcinoma
Kishore S, Friedman T, Madoff DC. Update on Embolization Therapies for Hepatocellular Carcinoma. Current Oncology Reports 2017, 19: 40. PMID: 28421483, DOI: 10.1007/s11912-017-0597-2.Peer-Reviewed Original ResearchConceptsEmbolization therapyHepatocellular carcinomaFuture liver remnant hypertrophyPortal vein tumor thrombusPlanned hepatic resectionStage C diseaseBCLC stage AEarly-stage patientsManagement of patientsSafety of resectionVein tumor thrombusRadiation lobectomyRadiation segmentectomyUnresectable HCCUnifocal diseaseHepatic resectionVein embolizationBCLC stageStage patientsSurvival benefitTumor thrombusAblative optionsB diseaseC diseaseDifferent therapies