2011
Resolution of Long-Standing Necrobiosis Lipoidica Diabeticorum (NLD) Lesion After Restoration of Euglycemia Following Successful Pancreas After Kidney (PAK) Transplantation: A Case Report
Mazur M, Lowney A, Prigoff J, Heilman R, Chakkera H, Moss A, Mulligan D, Reddy K, Hamawi K. Resolution of Long-Standing Necrobiosis Lipoidica Diabeticorum (NLD) Lesion After Restoration of Euglycemia Following Successful Pancreas After Kidney (PAK) Transplantation: A Case Report. Transplantation Proceedings 2011, 43: 3296-3298. PMID: 22099781, DOI: 10.1016/j.transproceed.2011.10.005.Peer-Reviewed Original ResearchConceptsNecrobiosis lipoidica diabeticorumKidney transplantationPancreas transplantationType I diabetic recipientsTight diabetic controlInflammatory skin disorderRestoration of euglycemiaSuccessful pancreasDiabetic controlDiabetes mellitusDiabetic recipientsImmunosuppressive agentsCase reportUnknown causeCase of resolutionConsistent efficacySkin disordersTransplantationEuglycemiaPatientsPancreasTreatmentImmunosuppressionMellitusRegimen
2010
Outcomes After Simultaneous Pancreas and Kidney Transplantation and the Discriminative Ability of the C-peptide Measurement Pretransplant Among Type 1 and Type 2 Diabetes Mellitus
Chakkera HA, Bodner JK, Heilman RL, Mulligan DC, Moss AA, Mekeel KL, Mazur MJ, Hamawi K, Ray RM, Beck GL, Reddy KS. Outcomes After Simultaneous Pancreas and Kidney Transplantation and the Discriminative Ability of the C-peptide Measurement Pretransplant Among Type 1 and Type 2 Diabetes Mellitus. Transplantation Proceedings 2010, 42: 2650-2652. PMID: 20832562, PMCID: PMC3060052, DOI: 10.1016/j.transproceed.2010.04.065.Peer-Reviewed Original ResearchMeSH KeywordsAdultC-PeptideCreatinineDiabetes Mellitus, Type 1Diabetes Mellitus, Type 2Diabetic NephropathiesDiabetic RetinopathyFemaleFollow-Up StudiesGlycated HemoglobinGraft RejectionHumansKidney Failure, ChronicKidney TransplantationMaleMiddle AgedPancreas TransplantationRetrospective StudiesSurvival AnalysisTissue DonorsConceptsEnd-stage renal diseaseType of diabetesC-peptideSimultaneous pancreasKidney transplantationPatient survivalGlutamic acid decarboxylase antibodiesType 2 diabetes mellitusDetectable C-peptideMean creatinine clearanceRenal Disease equationModification of DietBody mass indexC-peptide measurementsRegression survival analysisGlycosylate hemoglobinDiabetic ketoacidosisESRD patientsPancreas transplantationT2DM patientsCreatinine clearanceDecarboxylase antibodiesOral hypoglycemicsRenal replacementDiabetes mellitusASSOCIATION OF A COMPOSITE SET OF PREDICTORS PRE TRANSPLANTATION AND NEW ONSET DIABETES MELLITUS AFTER KIDNEY TRANSPLANTATION
Chakkera H, Devarapalli Y, Reddy K, Mulligan D, Mazur M, Hamawi K, Moss A, Mekeel K, Swanson C, Heilman R. ASSOCIATION OF A COMPOSITE SET OF PREDICTORS PRE TRANSPLANTATION AND NEW ONSET DIABETES MELLITUS AFTER KIDNEY TRANSPLANTATION. Transplantation 2010, 90: 928. DOI: 10.1097/00007890-201007272-01820.Peer-Reviewed Original ResearchRelationship between Inpatient Hyperglycemia and Insulin Treatment after Kidney Transplantation and Future New Onset Diabetes Mellitus
Chakkera HA, Knowler WC, Devarapalli Y, Weil EJ, Heilman RL, Dueck A, Mulligan DC, Reddy KS, Moss AA, Mekeel KL, Mazur MJ, Hamawi K, Castro JC, Cook CB. Relationship between Inpatient Hyperglycemia and Insulin Treatment after Kidney Transplantation and Future New Onset Diabetes Mellitus. Clinical Journal Of The American Society Of Nephrology 2010, 5: 1669-1675. PMID: 20558559, PMCID: PMC2974410, DOI: 10.2215/cjn.09481209.Peer-Reviewed Original ResearchConceptsKidney transplant recipientsInpatient hyperglycemiaKidney transplantationTransplant recipientsInsulin therapyNondiabetic kidney transplant recipientsDevelopment of NODATRisk of NODATNew-onset diabetesKidney transplant surgeryCapillary blood glucoseNondiabetic patientsYear posttransplantCardiovascular eventsNew onsetDiabetes mellitusMedical therapyAdjusted analysisStudy cohortRetrospective studyTransplant surgeryBlood glucoseSerum glucoseInsulin treatmentNODAT
2009
Pilot Study: Association of Traditional and Genetic Risk Factors and New-Onset Diabetes Mellitus Following Kidney Transplantation
Chakkera HA, Hanson RL, Raza SM, DiStefano JK, Millis MP, Heilman RL, Mulligan DC, Reddy KS, Mazur MJ, Hamawi K, Moss AA, Mekeel KL, Cerhan JR. Pilot Study: Association of Traditional and Genetic Risk Factors and New-Onset Diabetes Mellitus Following Kidney Transplantation. Transplantation Proceedings 2009, 41: 4172-4177. PMID: 20005362, PMCID: PMC3478878, DOI: 10.1016/j.transproceed.2009.08.063.Peer-Reviewed Original ResearchConceptsNew-onset diabetes mellitusDiabetes mellitusRisk factorsKidney transplantationTransplant recipientsFamily historyType 2 diabetes mellitusDevelopment of NODATKidney transplant recipientsTraditional risk factorsGenetic polymorphismsPositive family historyCommon risk factorsGenetic risk factorsLogistic regression modelsNODAT developmentNODAT riskPretransplant obesityNew onsetKidney transplantStudy cohortInsulin secretionNODATT2DMMellitus
2006
Acute Rejection Risk in Kidney Transplant Recipients on Steroid-Avoidance Immunosuppression Receiving Induction With Either Antithymocyte Globulin or Basiliximab
Heilman RL, Reddy KS, Mazur MJ, Moss AA, Post DJ, Petrides S, Mulligan DC. Acute Rejection Risk in Kidney Transplant Recipients on Steroid-Avoidance Immunosuppression Receiving Induction With Either Antithymocyte Globulin or Basiliximab. Transplantation Proceedings 2006, 38: 1307-1313. PMID: 16797289, DOI: 10.1016/j.transproceed.2006.02.116.Peer-Reviewed Original ResearchConceptsBiopsy-proven acute rejectionSteroid avoidance immunosuppressionKidney transplant recipientsAntithymocyte globulinAcute rejectionTransplant recipientsMonths posttransplantationAcute rejection-free survivalType 1 diabetes mellitusRabbit antithymocyte globulinRejection-free survivalAcute rejection riskInduction therapyMaintenance immunosuppressionProtocol biopsiesRapid discontinuationMost patientsDiabetes mellitusMedian timeLower incidenceRejection riskBasiliximabImmunosuppressionDay 4Overall risk