Impact of Subclinical Inflammation on the Development of Interstitial Fibrosis and Tubular Atrophy in Kidney Transplant Recipients
Heilman RL, Devarapalli Y, Chakkera HA, Mekeel KL, Moss AA, Mulligan DC, Mazur MJ, Hamawi K, Williams JW, Reddy KS. Impact of Subclinical Inflammation on the Development of Interstitial Fibrosis and Tubular Atrophy in Kidney Transplant Recipients. American Journal Of Transplantation 2010, 10: 563-570. PMID: 20121731, DOI: 10.1111/j.1600-6143.2009.02966.x.Peer-Reviewed Original ResearchConceptsIF/TA scoreRapid steroid withdrawalSubclinical acute rejectionClinical acute rejectionSubclinical inflammationGroup 2Group 1Group 3Acute rejectionTubular atrophyInterstitial fibrosisGroup 4IF/TAProtocol biopsy findingsKidney transplant recipientsTA scoresProtocol biopsiesSteroid withdrawalTransplant recipientsBiopsy findingsInterstitial inflammationMore patientsMonths 1High riskPatients