Activation of the Calcium Sensing Receptor (casr) Prevents Secretagogue-Induced Diarrhea in the Rat Small Intestine
Finotti M, Lysyy T, Caturegli G, Barahona M, Maina R, D'Amico F, Mulligan D, Geibel J. Activation of the Calcium Sensing Receptor (casr) Prevents Secretagogue-Induced Diarrhea in the Rat Small Intestine. Transplantation 2018, 102: s669. DOI: 10.1097/01.tp.0000543607.00911.f4.Peer-Reviewed Original ResearchOral rehydration solutionSmall intestineColon segmentsIntestinal secretionNumerous body tissuesSeverity of diarrheaDistal small intestineMale Sprague-DawleyCalcium-sensing receptorDistal portionLuminal calcium concentrationRat small intestineAbsence of forskolinCalcium perfusionProphylactic therapyAntibiotic therapyLeading causePotent secretagogueRehydration solutionSprague-DawleyElectrolyte homeostasisDiarrheaPotential treatmentSecretion profileAbsorption of fluidGenerating vascular conduits: from tissue engineering to three-dimensional bioprinting
Maina RM, Barahona MJ, Finotti M, Lysyy T, Geibel P, D’Amico F, Mulligan D, Geibel JP. Generating vascular conduits: from tissue engineering to three-dimensional bioprinting. Innovative Surgical Sciences 2018, 3: 203-213. PMID: 31579784, PMCID: PMC6604577, DOI: 10.1515/iss-2018-0016.Peer-Reviewed Original ResearchArtery diseaseVascular conduitsVascular diseaseAutologous graftsNative vesselsSuitable vascular conduitInternal mammary arteryPeripheral vascular diseaseRat vascular smooth muscle cellsThird of patientsCoronary artery diseaseCarotid artery diseaseVascular smooth muscle cellsStandard of careLimb-saving procedureSmooth muscle cellsMultivessel diseaseDonor graftsMammary arteryPoor outcomeSaphenous veinLeading causeVascular interventionsGraftMuscle cells