2011
Impact of Acute Rejection on Kidney Allograft Outcomes in Recipients on Rapid Steroid Withdrawal
Heilman RL, Nijim S, Chakkera HA, Devarapalli Y, Moss AA, Mulligan DC, Mazur MJ, Hamawi K, Williams JW, Reddy KS. Impact of Acute Rejection on Kidney Allograft Outcomes in Recipients on Rapid Steroid Withdrawal. Journal Of Transplantation 2011, 2011: 583981. PMID: 21647349, PMCID: PMC3103882, DOI: 10.1155/2011/583981.Peer-Reviewed Original ResearchClinical acute rejectionRapid steroid withdrawalDeath-censored graft survivalKidney transplant recipientsSubclinical rejectionGraft survivalControl groupAcute rejectionSteroid withdrawalTransplant recipientsRejection groupCR groupDeceased donor kidney transplantInferior graft survivalMean HLA mismatchesKidney allograft outcomesDonor kidney transplantsAllograft outcomesAllograft survivalProtocol biopsiesHLA mismatchesBorderline changesKidney transplantPrimary outcomePersistent inflammation
2010
Impact of Subclinical Inflammation on the Development of Interstitial Fibrosis and Tubular Atrophy in Kidney Transplant Recipients
Heilman RL, Devarapalli Y, Chakkera HA, Mekeel KL, Moss AA, Mulligan DC, Mazur MJ, Hamawi K, Williams JW, Reddy KS. Impact of Subclinical Inflammation on the Development of Interstitial Fibrosis and Tubular Atrophy in Kidney Transplant Recipients. American Journal Of Transplantation 2010, 10: 563-570. PMID: 20121731, DOI: 10.1111/j.1600-6143.2009.02966.x.Peer-Reviewed Original ResearchConceptsIF/TA scoreRapid steroid withdrawalSubclinical acute rejectionClinical acute rejectionSubclinical inflammationGroup 2Group 1Group 3Acute rejectionTubular atrophyInterstitial fibrosisGroup 4IF/TAProtocol biopsy findingsKidney transplant recipientsTA scoresProtocol biopsiesSteroid withdrawalTransplant recipientsBiopsy findingsInterstitial inflammationMore patientsMonths 1High riskPatients
2008
SIMULTANEOUS KIDNEY PANCREAS TRANSPLANTATION USING RAPID STEROID TAPER WITH PROTOCOL BIOPSIES: COMPARISON OF R-ATG VERSUS ALEMTUZUMAB
Heilman R, Reddy K, Moss A, Mazur M, Mekeel K, Chakkera H, Post D, Mulligan D. SIMULTANEOUS KIDNEY PANCREAS TRANSPLANTATION USING RAPID STEROID TAPER WITH PROTOCOL BIOPSIES: COMPARISON OF R-ATG VERSUS ALEMTUZUMAB. Transplantation 2008, 86: 50. DOI: 10.1097/01.tp.0000332690.44585.05.Peer-Reviewed Original Research
2007
Clinical factors associated with graft fibrosis in kidney‐transplant recipients on steroid‐avoidance immunosuppression
Heilman RL, Chakkera HA, Reddy KS, Colby TV, Moss AA, Williams JW, Mazur MJ, Petrides S, Mulligan DC. Clinical factors associated with graft fibrosis in kidney‐transplant recipients on steroid‐avoidance immunosuppression. Clinical Transplantation 2007, 22: 309-315. PMID: 18482051, DOI: 10.1111/j.1399-0012.2007.00786.x.Peer-Reviewed Original ResearchConceptsSteroid avoidance immunosuppressionKidney-pancreas transplant recipientsOne-year biopsyKidney transplant recipientsBK nephropathySerum creatinineProtocol biopsiesRecipient ageTransplant recipientsGraft fibrosisUnadjusted logistic regression analysisLower body mass indexMultivariate logistic regression modelCI scoresPrimary kidney transplantsPancreas transplant recipientsBody mass indexInterstitial cellular infiltrateLogistic regression analysisLogistic regression modelsAcute rejectionAntigen mismatchesAntithymocyte globulinGraft outcomeKidney transplant
2006
CLINICAL VARIABLES ASSOCIATED WITH GRAFT FIBROSIS (GF) ON 12 MONTH PROTOCOL BIOPSY IN KIDNEY TRANSPLANT RECIPIENTS ON STEROID AVOIDANCE IMMUNOSUPPRESSION (SA).
Heilman R, Reddy K, Chakkera H, Mazur M, Moss A, Williams J, Colby T, Petrides S, Mulligan D. CLINICAL VARIABLES ASSOCIATED WITH GRAFT FIBROSIS (GF) ON 12 MONTH PROTOCOL BIOPSY IN KIDNEY TRANSPLANT RECIPIENTS ON STEROID AVOIDANCE IMMUNOSUPPRESSION (SA). Transplantation 2006, 82: 461-462. DOI: 10.1097/00007890-200607152-01187.Peer-Reviewed Original ResearchAcute Rejection Risk in Kidney Transplant Recipients on Steroid-Avoidance Immunosuppression Receiving Induction With Either Antithymocyte Globulin or Basiliximab
Heilman RL, Reddy KS, Mazur MJ, Moss AA, Post DJ, Petrides S, Mulligan DC. Acute Rejection Risk in Kidney Transplant Recipients on Steroid-Avoidance Immunosuppression Receiving Induction With Either Antithymocyte Globulin or Basiliximab. Transplantation Proceedings 2006, 38: 1307-1313. PMID: 16797289, DOI: 10.1016/j.transproceed.2006.02.116.Peer-Reviewed Original ResearchConceptsBiopsy-proven acute rejectionSteroid avoidance immunosuppressionKidney transplant recipientsAntithymocyte globulinAcute rejectionTransplant recipientsMonths posttransplantationAcute rejection-free survivalType 1 diabetes mellitusRabbit antithymocyte globulinRejection-free survivalAcute rejection riskInduction therapyMaintenance immunosuppressionProtocol biopsiesRapid discontinuationMost patientsDiabetes mellitusMedian timeLower incidenceRejection riskBasiliximabImmunosuppressionDay 4Overall risk