2017
Allograft transmission of hepatitis C during the window period: Weighing the new risks and costs in the era of donor shortage
Choe J, Merola J, Kulkarni S, Mulligan DC. Allograft transmission of hepatitis C during the window period: Weighing the new risks and costs in the era of donor shortage. Clinical Transplantation 2017, 31 PMID: 28643333, DOI: 10.1111/ctr.13022.Peer-Reviewed Original ResearchAdultDonor SelectionFemaleHepatitis CHumansKidney Failure, ChronicKidney TransplantationMaleMiddle AgedPostoperative Complications
2016
Belatacept and Eculizumab for Treatment of Calcineurin Inhibitor-induced Thrombotic Microangiopathy After Kidney Transplantation: Case Report
Merola J, Yoo PS, Schaub J, Smith JD, Rodriguez-Davalos MI, Tichy E, Mulligan DC, Asch W, Formica R, Kashgarian M, Kulkarni S. Belatacept and Eculizumab for Treatment of Calcineurin Inhibitor-induced Thrombotic Microangiopathy After Kidney Transplantation: Case Report. Transplantation Proceedings 2016, 48: 3106-3108. PMID: 27932157, DOI: 10.1016/j.transproceed.2016.04.005.Peer-Reviewed Original ResearchConceptsCalcineurin inhibitorsHemolytic uremic syndromeThrombotic microangiopathyKidney transplantationUremic syndromeMinimization of CNIsAtypical hemolytic uremic syndromeWithdrawal of tacrolimusEarly graft lossFavorable clinical courseGraft dysfunctionGraft lossImmunosuppression strategiesUsual therapyClinical courseCase reportCTLA-4Endothelial reactionFrequent causeChallenging causeUncontrolled activationMonoclonal antibodiesCellular destructionMicroangiopathyComponent C5Perioperative outcomes of coronary artery bypass graft in renal transplant recipients in the United States: results from the Nationwide Inpatient Sample
Tooley JE, Bohl DD, Kulkarni S, Rodriguez‐Davalos M, Mangi A, Mulligan DC, Yoo PS. Perioperative outcomes of coronary artery bypass graft in renal transplant recipients in the United States: results from the Nationwide Inpatient Sample. Clinical Transplantation 2016, 30: 1258-1263. PMID: 27440000, DOI: 10.1111/ctr.12816.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overCoronary Artery BypassCoronary Artery DiseaseDatabases, FactualFemaleHospital CostsHospital MortalityHumansKidney TransplantationLength of StayLinear ModelsLogistic ModelsMaleMiddle AgedPostoperative ComplicationsRenal DialysisRenal Insufficiency, ChronicRetrospective StudiesTreatment OutcomeUnited StatesYoung AdultConceptsChronic kidney diseaseNationwide Inpatient SampleLength of stayCKD patientsCABG surgeryHospital mortalityPerioperative outcomesInpatient SampleCardiovascular diseaseCoronary artery bypass graftKidney transplant patientsRenal transplant recipientsRetrospective cohort studyArtery bypass graftRate of complicationsTotal hospital chargesBetter perioperative outcomesCause of morbidityCost of hospitalizationNumber one causeGraft lossPerioperative complicationsTransplant patientsTransplant recipientsCohort studyPostoperative delirium is associated with increased intensive care unit and hospital length of stays after liver transplantation
Bhattacharya B, Maung A, Barre K, Maerz L, Rodriguez-Davalos MI, Schilsky M, Mulligan DC, Davis KA. Postoperative delirium is associated with increased intensive care unit and hospital length of stays after liver transplantation. Journal Of Surgical Research 2016, 207: 223-228. PMID: 27979481, DOI: 10.1016/j.jss.2016.08.084.Peer-Reviewed Original ResearchConceptsLiver transplantationHospital lengthEnd-stage liver disease (MELD) scoreIntensive care unit LOSHigher preoperative modelImportant postoperative complicationLiver Disease scoreLiver transplant patientsImpact of deliriumTertiary care centerRetrospective case seriesUrinary tract infectionFurther prospective studiesIntensive care unitLong-term outcomesSpecific risk factorsFrequency of hospitalPaucity of dataPostoperative deliriumPostoperative hospitalPostoperative complicationsTransplant patientsVentilator daysAdult patientsDelirious patients
2015
Non‐alcoholic fatty liver disease following liver transplantation: a clinical review
Merola J, Liapakis A, Mulligan DC, Yoo PS. Non‐alcoholic fatty liver disease following liver transplantation: a clinical review. Clinical Transplantation 2015, 29: 728-737. PMID: 26147308, DOI: 10.1111/ctr.12585.Peer-Reviewed Original ResearchMeSH KeywordsCardiovascular DiseasesCombined Modality TherapyHumansLiver TransplantationMetabolic SyndromeNon-alcoholic Fatty Liver DiseasePostoperative ComplicationsRisk FactorsTreatment OutcomeConceptsNon-alcoholic steatohepatitisLiver transplantationRisk factorsNon-alcoholic fatty liver diseasePost-transplant metabolic syndromePost-transplant settingCardiovascular risk factorsPost-transplantation outcomesSignificant survival benefitFatty liver diseaseCause of deathCardiovascular mortalitySurvival benefitMetabolic syndromeLiver diseaseClinical reviewPatient populationSurgical approachTreatment approachesTransplantationRecent evidenceIndicationsSteatohepatitisTransplantSyndrome
2012
Endoscopic treatment of anastomotic biliary strictures after living donor liver transplantation: outcomes after maximal stent therapy
Hsieh TH, Mekeel KL, Crowell MD, Nguyen CC, Das A, Aqel BA, Carey EJ, Byrne TJ, Vargas HE, Douglas DD, Mulligan DC, Harrison ME. Endoscopic treatment of anastomotic biliary strictures after living donor liver transplantation: outcomes after maximal stent therapy. Gastrointestinal Endoscopy 2012, 77: 47-54. PMID: 23062758, DOI: 10.1016/j.gie.2012.08.034.Peer-Reviewed Original ResearchMeSH KeywordsAlanine TransaminaseAlkaline PhosphataseAspartate AminotransferasesBiliary Tract DiseasesBilirubinCholangiopancreatography, Endoscopic RetrogradeCholestasisEndoscopy, Digestive SystemFemaleFollow-Up StudiesHumansLiver TransplantationLiving DonorsMalePostoperative ComplicationsRecurrenceRetrospective StudiesStentsTreatment OutcomeConceptsLiving-donor liver transplantationAnastomotic biliary stricturesEndoscopic retrograde cholangiographyPercutaneous transhepatic cholangiographyBiliary stricturesEndoscopic therapyLiver transplantationEndoscopic treatmentRetrograde cholangiographySurgical revisionRetrospective studyTertiary care academic medical centerAggressive endoscopic approachStent placement strategyUnsuccessful endoscopic therapyDonor liver transplantationOptimal endoscopic treatmentAcademic medical centerDuct anastomosisInitial therapyBile leakageEndoscopic dilationBalloon dilationCommon complicationComplication rate
2011
Laparoscopic Distal Pancreatectomy
Mekeel KL, Moss AA, Reddy KS, Mulligan DC, Harold KL. Laparoscopic Distal Pancreatectomy. Surgical Laparoscopy Endoscopy & Percutaneous Techniques 2011, 21: 362-365. PMID: 22002275, DOI: 10.1097/sle.0b013e31822e0ea8.Peer-Reviewed Original ResearchConceptsLaparoscopic distal pancreatectomyDistal pancreatectomyLaparoscopic pancreatectomySpleen-preserving groupSpleen-preserving pancreatectomyLess blood lossShorter operative timeConcomitant splenectomyInfectious complicationsSplenectomy groupSurgical complicationsBlood lossPancreatic leakSplenic preservationOperative timeRetrospective reviewHand assistanceSplenic vesselsPancreatectomyAnatomic concernsPatientsDelicate dissectionComplicationsSplenectomySpleen
2010
Early Graft Function After Laparoscopically Procured Living Donor Kidney Transplantation
Tyson M, Castle E, Andrews P, Heilman R, Mekeel K, Moss A, Mulligan D, Reddy K. Early Graft Function After Laparoscopically Procured Living Donor Kidney Transplantation. Journal Of Urology 2010, 184: 1434-1439. PMID: 20727548, DOI: 10.1016/j.juro.2010.06.013.Peer-Reviewed Original ResearchMeSH KeywordsAdultFemaleHumansKidney TransplantationLaparoscopyLiving DonorsMaleMiddle AgedNephrectomyPostoperative ComplicationsRisk FactorsTime FactorsConceptsPoor early graft functionEarly graft functionLiving-donor kidney transplantationGraft functionDonor kidney transplantationAcute rejectionKidney transplantationMultivariate logistic regression modelGraft function groupDelayed graft functionDonor kidney transplantsInstitutional review boardLogistic regression modelsAllograft survivalGraft nephrectomyVascular complicationsKidney transplantPerioperative parametersIndependent predictorsTransplantation databaseClinical outcomesPatient survivalBlack ethnicityMale genderDonor age
2009
Pilot Study: Association of Traditional and Genetic Risk Factors and New-Onset Diabetes Mellitus Following Kidney Transplantation
Chakkera HA, Hanson RL, Raza SM, DiStefano JK, Millis MP, Heilman RL, Mulligan DC, Reddy KS, Mazur MJ, Hamawi K, Moss AA, Mekeel KL, Cerhan JR. Pilot Study: Association of Traditional and Genetic Risk Factors and New-Onset Diabetes Mellitus Following Kidney Transplantation. Transplantation Proceedings 2009, 41: 4172-4177. PMID: 20005362, PMCID: PMC3478878, DOI: 10.1016/j.transproceed.2009.08.063.Peer-Reviewed Original ResearchConceptsNew-onset diabetes mellitusDiabetes mellitusRisk factorsKidney transplantationTransplant recipientsFamily historyType 2 diabetes mellitusDevelopment of NODATKidney transplant recipientsTraditional risk factorsGenetic polymorphismsPositive family historyCommon risk factorsGenetic risk factorsLogistic regression modelsNODAT developmentNODAT riskPretransplant obesityNew onsetKidney transplantStudy cohortInsulin secretionNODATT2DMMellitusLiving donor liver transplantation and donor graft size: How small can we go to reduce risk to the donor and what is the cost to the recipient?
Mulligan D. Living donor liver transplantation and donor graft size: How small can we go to reduce risk to the donor and what is the cost to the recipient? Liver Transplantation 2009, 15: 1392-1394. PMID: 19877257, DOI: 10.1002/lt.21922.Peer-Reviewed Original ResearchMeSH KeywordsHepatectomyHumansLiver FailureLiver TransplantationLiving DonorsOrgan SizePostoperative ComplicationsRisk FactorsHemobilia and pancreatitis after liver transplant biopsy
Li F, Mekeel KL, Eleid M, Harrison ME, Reddy KS, Moss AA, Mulligan DC. Hemobilia and pancreatitis after liver transplant biopsy. Liver Transplantation 2009, 15: 350-351. PMID: 19243004, DOI: 10.1002/lt.21619.Peer-Reviewed Original Research
2007
Laparoscopic incisional hernia repair after liver transplantation
Mekeel K, Mulligan D, Reddy KS, Moss A, Harold K. Laparoscopic incisional hernia repair after liver transplantation. Liver Transplantation 2007, 13: 1576-1581. PMID: 17969189, DOI: 10.1002/lt.21290.Peer-Reviewed Original ResearchConceptsLaparoscopic incisional hernia repairIncisional hernia repairLAP groupLiver transplantationHernia repairOP groupMore patientsLaparoscopic ventral hernia repairTime of transplantationLength of stayVentral hernia repairNontransplant patientsPrimary immunosuppressionWound complicationsRecurrent ascitesLaparoscopic approachMesh removalOpen repairRetrospective reviewDecreased incidenceMesh infectionIncisional herniaLower riskPatientsTransplantation
2005
Steroid Avoidance Immunosuppression in Low-Risk Kidney Transplant Recipients
Heilman R, Mazur M, Reddy K, Moss A, Post D, Mulligan D. Steroid Avoidance Immunosuppression in Low-Risk Kidney Transplant Recipients. Transplantation Proceedings 2005, 37: 1785-1788. PMID: 15919466, DOI: 10.1016/j.transproceed.2005.02.106.Peer-Reviewed Original ResearchConceptsKidney transplant recipientsLow-risk kidney transplant recipientsChronic allograft nephropathyPostoperative day 3Steroid avoidanceTransplant recipientsLow-immunologic risk kidney transplant recipientsDay 3Anti-thymocyte globulin inductionRabbit anti-thymocyte globulinRisk kidney transplant recipientsIncidence of PTDMPositive flow crossmatchSteroid avoidance immunosuppressionTrough tacrolimus levelsAnti-thymocyte globulinGraft survival ratesSerum creatinine levelsShort-term safetyRecent clinical trialsDay of transplantationActuarial patientAcute rejectionAllograft nephropathyGlobulin induction
2003
Subcutaneous metastasis at a surgical drain site after the resection of pancreatic cancer
St. Peter SD, Nguyen CC, Mulligan DC, Moss AA. Subcutaneous metastasis at a surgical drain site after the resection of pancreatic cancer. Journal Of Gastrointestinal Cancer 2003, 33: 111. PMID: 14716058, DOI: 10.1385/ijgc:33:2-3:111.Peer-Reviewed Original ResearchMeSH KeywordsAgedDrainageFemaleHumansNeoplasm SeedingPancreatic NeoplasmsPostoperative ComplicationsSkin NeoplasmsSurgical EquipmentConceptsCurative intentPancreatic cancerSurgical drain siteImpact of surgeryTumor growth characteristicsCutaneous recurrenceCutaneous metastasesPalliative procedureSkin metastasesSubcutaneous metastasesSurgical drainsTumor burdenSurgical controlPeritoneal cavityUnusual caseDrain siteResectionAggressive natureMetastasisRecurrenceCancerDiseaseRare eventComplicationsSurgery
1998
Cost analysis of four strategies for prevention of CMV infection in liver transplant recipients
Post AB, Mulligan DC, Bush W. Cost analysis of four strategies for prevention of CMV infection in liver transplant recipients. Transplantation Proceedings 1998, 30: 2102-2103. PMID: 9723406, DOI: 10.1016/s0041-1345(98)00553-3.Peer-Reviewed Original Research
1997
Reduction of early rejection in adult liver transplantation with ATG induction therapy
Schulak J, May E, Post A, Fasola C, Mulligan D, Sterling R. Reduction of early rejection in adult liver transplantation with ATG induction therapy. Transplantation Proceedings 1997, 29: 555-556. PMID: 9123126, DOI: 10.1016/s0041-1345(96)00264-3.Peer-Reviewed Original Research
1995
Use of anti-hepatitis C virus seropositive organs in liver transplantation.
Mulligan DC, Goldstein RM, Crippin JS, Abouljoud MS, Levy MF, Husberg BS, Gonwa TA, Foster BR, Tillery GW, Klintmalm GB. Use of anti-hepatitis C virus seropositive organs in liver transplantation. Transplantation Proceedings 1995, 27: 1204-5. PMID: 7878850.Peer-Reviewed Original Research