2011
A randomized, multicenter study comparing steroid‐free immunosuppression and standard immunosuppression for liver transplant recipients with chronic hepatitis C
Klintmalm GB, Davis GL, Teperman L, Netto GJ, Washburn K, Rudich SM, Pomfret EA, Vargas HE, Brown R, Eckhoff D, Pruett TL, Roberts J, Mulligan DC, Charlton MR, Heffron TG, Ham JM, Douglas DD, Sher L, Baliga PK, Kinkhabwala M, Koneru B, Abecassis M, Millis M, Jennings LW, Fasola CG. A randomized, multicenter study comparing steroid‐free immunosuppression and standard immunosuppression for liver transplant recipients with chronic hepatitis C. Liver Transplantation 2011, 17: 1394-1403. PMID: 21850690, DOI: 10.1002/lt.22417.Peer-Reviewed Original ResearchMeSH KeywordsAdrenal Cortex HormonesAntibodies, Monoclonal, HumanizedAntiviral AgentsBiopsyChi-Square DistributionDaclizumabDrug Therapy, CombinationFemaleGraft RejectionHepacivirusHepatitis C, ChronicHumansImmunoglobulin GImmunosuppressive AgentsKaplan-Meier EstimateLiver FailureLiver TransplantationMaleMiddle AgedMycophenolic AcidProportional Hazards ModelsProspective StudiesRecurrenceRisk AssessmentRisk FactorsRNA, ViralSurvival RateTacrolimusTime FactorsTreatment OutcomeUnited StatesConceptsAcute cellular rejectionSteroid-free immunosuppressionLiver transplant recipientsHCV recurrenceMycophenolate mofetilTransplant recipientsHCV RNA-positive subjectsHepatitis C virus infectionSevere HCV recurrenceSteroid-free groupC virus infectionChronic hepatitis CGraft survival ratesProportion of patientsLiver biopsy samplesCellular rejectionChronic HCVStandard immunosuppressionSteroid sparingHepatitis CLess diabetesMulticenter trialMulticenter studyPatient survivalArm 1
2002
A randomized, prospective, double-blinded evaluation of selective bowel decontamination in liver transplantation
Hellinger WC, Yao JD, Alvarez S, Blair JE, Cawley JJ, Paya CV, O’Brien P, Spivey JR, Dickson RC, Harnois DM, Douglas DD, Hughes CB, Nguyen JH, Mulligan DC, Steers JL. A randomized, prospective, double-blinded evaluation of selective bowel decontamination in liver transplantation. Transplantation 2002, 73: 1904-1909. PMID: 12131685, DOI: 10.1097/00007890-200206270-00009.Peer-Reviewed Original ResearchConceptsSelective bowel decontaminationLiver transplantationRate of infectionDay 0Bowel decontaminationMedical careBacterial infectionsDouble-blinded fashionDouble-blinded evaluationGentamicin 80Mortal complicationsUncontrolled trialsSwab culturesTreatment groupsTransplantationPatientsDay 21Day 60Routine useInfectionPositive floraNegative floraFecal cultureCareDeathThrombendvenectomy for Organized Portal Vein Thrombosis at the Time of Liver Transplantation
Molmenti EP, Roodhouse TW, Molmenti H, Jaiswal K, Jung G, Marubashi S, Sanchez EQ, Gogel B, Levy MF, Goldstein RM, Fasola CG, Elliott EE, Bursac N, Mulligan D, Gonwa TA, Klintmalm GB. Thrombendvenectomy for Organized Portal Vein Thrombosis at the Time of Liver Transplantation. Annals Of Surgery 2002, 235: 292-296. PMID: 11807371, PMCID: PMC1422428, DOI: 10.1097/00000658-200202000-00019.Peer-Reviewed Original ResearchMeSH KeywordsContraindicationsFemaleHumansLiver TransplantationMaleMiddle AgedPortal VeinProspective StudiesThrombectomyThrombosisConceptsPortal vein thrombosisGraft survival ratesTime of transplantationLiver transplantationVein thrombosisMale patientsFemale patientsLiver diseasePortal veinControl groupSurvival rateEnd-stage liver diseaseOrthotopic liver transplantOrthotopic liver transplantationFirst postoperative dayIntensive care unitLength of stayCryptogenic cirrhosisDaily aspirinPVT groupPVT patientsTacrolimus immunosuppressionLiver transplantTransplant recipientsPostoperative day
1995
A Comparison Of Treatment With Transjugular Intrahepatic Portosystemic Shunt Or Distal Splenorenal Shunt In The Management Of Variceal Bleeding Prior To Liver Transplantation
Abouljoud M, Levy M, Rees C, Diamond N, Lee S, Mulligan D, Goldstein R, Husberg B, Gonwa T, Klintmalm G. A Comparison Of Treatment With Transjugular Intrahepatic Portosystemic Shunt Or Distal Splenorenal Shunt In The Management Of Variceal Bleeding Prior To Liver Transplantation. Transplantation 1995, 59: 226-229. PMID: 7839445, DOI: 10.1097/00007890-199501270-00013.Peer-Reviewed Original ResearchConceptsTransjugular intrahepatic portosystemic shuntDistal splenorenal shuntIntrahepatic portosystemic shuntDSRS groupVariceal bleedingLiver transplantationSurgical shuntsSplenorenal shuntLiver diseasePortosystemic shuntTIPS groupRole of TIPSPrevious transjugular intrahepatic portosystemic shuntEnd-stage liver diseaseChild-Pugh C patientsIntraoperative hemodynamic measurementsSubsequent transplant procedureAdvanced liver diseaseLiver transplant candidatesLiver transplant recipientsRecurrent variceal bleedingGroup of patientsFirst-line managementBlood flow measurementsComparison of treatments