2011
Resolution of Long-Standing Necrobiosis Lipoidica Diabeticorum (NLD) Lesion After Restoration of Euglycemia Following Successful Pancreas After Kidney (PAK) Transplantation: A Case Report
Mazur M, Lowney A, Prigoff J, Heilman R, Chakkera H, Moss A, Mulligan D, Reddy K, Hamawi K. Resolution of Long-Standing Necrobiosis Lipoidica Diabeticorum (NLD) Lesion After Restoration of Euglycemia Following Successful Pancreas After Kidney (PAK) Transplantation: A Case Report. Transplantation Proceedings 2011, 43: 3296-3298. PMID: 22099781, DOI: 10.1016/j.transproceed.2011.10.005.Peer-Reviewed Original ResearchConceptsNecrobiosis lipoidica diabeticorumKidney transplantationPancreas transplantationType I diabetic recipientsTight diabetic controlInflammatory skin disorderRestoration of euglycemiaSuccessful pancreasDiabetic controlDiabetes mellitusDiabetic recipientsImmunosuppressive agentsCase reportUnknown causeCase of resolutionConsistent efficacySkin disordersTransplantationEuglycemiaPatientsPancreasTreatmentImmunosuppressionMellitusRegimenA Technique for Kidney Retransplantation After Simultaneous Kidney Pancreas Transplantation
Mekeel KL, Moss AA, Mulligan DC, Reddy KS. A Technique for Kidney Retransplantation After Simultaneous Kidney Pancreas Transplantation. Transplantation Proceedings 2011, 43: 1627-1628. PMID: 21693246, DOI: 10.1016/j.transproceed.2011.03.026.Peer-Reviewed Original ResearchMeSH KeywordsGlomerular Filtration RateHumansKidneyKidney TransplantationPancreasPancreas TransplantationOpen Sphincteroplasty for Benign Ampullary Stricture After Pancreas Transplantation
Mekeel KL, Moss AA, Mulligan DC, Reddy KS. Open Sphincteroplasty for Benign Ampullary Stricture After Pancreas Transplantation. American Journal Of Transplantation 2011, 11: 399-402. PMID: 21214856, DOI: 10.1111/j.1600-6143.2010.03369.x.Peer-Reviewed Original ResearchMeSH KeywordsAdultAmpulla of VaterConstriction, PathologicHumansKidney TransplantationMalePancreas TransplantationPancreatic DuctsSphincterotomy, Transduodenal
2010
Outcomes After Simultaneous Pancreas and Kidney Transplantation and the Discriminative Ability of the C-peptide Measurement Pretransplant Among Type 1 and Type 2 Diabetes Mellitus
Chakkera HA, Bodner JK, Heilman RL, Mulligan DC, Moss AA, Mekeel KL, Mazur MJ, Hamawi K, Ray RM, Beck GL, Reddy KS. Outcomes After Simultaneous Pancreas and Kidney Transplantation and the Discriminative Ability of the C-peptide Measurement Pretransplant Among Type 1 and Type 2 Diabetes Mellitus. Transplantation Proceedings 2010, 42: 2650-2652. PMID: 20832562, PMCID: PMC3060052, DOI: 10.1016/j.transproceed.2010.04.065.Peer-Reviewed Original ResearchMeSH KeywordsAdultC-PeptideCreatinineDiabetes Mellitus, Type 1Diabetes Mellitus, Type 2Diabetic NephropathiesDiabetic RetinopathyFemaleFollow-Up StudiesGlycated HemoglobinGraft RejectionHumansKidney Failure, ChronicKidney TransplantationMaleMiddle AgedPancreas TransplantationRetrospective StudiesSurvival AnalysisTissue DonorsConceptsEnd-stage renal diseaseType of diabetesC-peptideSimultaneous pancreasKidney transplantationPatient survivalGlutamic acid decarboxylase antibodiesType 2 diabetes mellitusDetectable C-peptideMean creatinine clearanceRenal Disease equationModification of DietBody mass indexC-peptide measurementsRegression survival analysisGlycosylate hemoglobinDiabetic ketoacidosisESRD patientsPancreas transplantationT2DM patientsCreatinine clearanceDecarboxylase antibodiesOral hypoglycemicsRenal replacementDiabetes mellitusAlemtuzumab with Rapid Steroid Taper in Simultaneous Kidney and Pancreas Transplantation: Comparison to Induction with Antithymocyte Globulin
Reddy K, Devarapalli Y, Mazur M, Hamawi K, Chakkera H, Moss A, Mekeel K, Post D, Heilman R, Mulligan D. Alemtuzumab with Rapid Steroid Taper in Simultaneous Kidney and Pancreas Transplantation: Comparison to Induction with Antithymocyte Globulin. Transplantation Proceedings 2010, 42: 2006-2008. PMID: 20692393, DOI: 10.1016/j.transproceed.2010.05.090.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAdrenal Cortex HormonesAlemtuzumabAntibodies, MonoclonalAntibodies, Monoclonal, HumanizedAntibodies, NeoplasmAntilymphocyte SerumCreatinineDrug Therapy, CombinationGlomerular Filtration RateGraft RejectionGraft SurvivalHumansImmunosuppressive AgentsKidney TransplantationMycophenolic AcidPancreas TransplantationPatient SelectionRetrospective StudiesConceptsRapid steroid taperAcute rejection episodesR-ATG groupR-ATGSimultaneous kidneySteroid taperBK nephropathyRejection episodesPancreas transplantationAlemtuzumab groupClinical acute rejection episodesRabbit antithymocyte globulin inductionAntithymocyte globulin inductionR-ATG inductionMean serum creatinineHistoric control groupPostoperative day 4Alemtuzumab inductionAntithymocyte globulinGlobulin inductionMaintenance immunosuppressionTransplant characteristicsGraft survivalCMV infectionCytomegalovirus infection
2009
ASTS Recommended Practice Guidelines for Controlled Donation after Cardiac Death Organ Procurement and Transplantation
Reich DJ, Mulligan DC, Abt PL, Pruett TL, Abecassis MM, D’Alessandro A, Pomfret EA, Freeman RB, Markmann JF, Hanto DW, Matas AJ, Roberts JP, Merion RM, Klintmalm GB, Committee T. ASTS Recommended Practice Guidelines for Controlled Donation after Cardiac Death Organ Procurement and Transplantation. American Journal Of Transplantation 2009, 9: 2004-2011. PMID: 19624569, DOI: 10.1111/j.1600-6143.2009.02739.x.Peer-Reviewed Original ResearchConceptsOrgan donationFavorable posttransplant outcomesOrgan acceptance criteriaOrgan procurement organizationsBrain death criteriaBiliary issuesDCD kidneysPancreas transplantationVentilatory supportPosttransplant outcomesCardiac deathTransplant centersIschemia timeDCD protocolsHopeless prognosisMachine perfusionBrain deathTransplant surgeonsOperative techniqueOrgan transplantationPractice guidelinesBest practice guidelinesOrgan procurementDonor characteristicsTransplantationOutcomes of Simultaneous Kidney–Pancreas Transplantation With Positive Cross-Match
Heilman R, Chakkera H, Mazur M, Petrides S, Moss A, Mekeel K, Mulligan D, Reddy K. Outcomes of Simultaneous Kidney–Pancreas Transplantation With Positive Cross-Match. Transplantation Proceedings 2009, 41: 303-306. PMID: 19249540, DOI: 10.1016/j.transproceed.2008.08.154.Peer-Reviewed Original ResearchMeSH KeywordsAlemtuzumabAntibodies, MonoclonalAntibodies, Monoclonal, HumanizedAntibodies, NeoplasmAntilymphocyte SerumDrug Therapy, CombinationFollow-Up StudiesGraft SurvivalHistocompatibility TestingHumansImmunoglobulins, IntravenousImmunosuppressive AgentsKidney TransplantationPancreas TransplantationRetrospective StudiesSurvival AnalysisTime FactorsTreatment OutcomeConceptsAntibody-mediated rejectionLow-dose intravenous immunoglobulinAcute cellular rejectionIntravenous immunoglobulinStudy groupControl groupAllograft survivalMycophenolate mofetilRisk of AMRSimultaneous pancreas-kidney transplant recipientsPancreas-kidney transplant recipientsSimultaneous kidney-pancreas transplantationDose intravenous immunoglobulinKidney-pancreas transplantationPositive cross matchRabbit antithymocyte globulinActuarial patient survivalKidney allograft survivalKidney transplant recipientsPancreas allograft survivalAcute rejectionAntithymocyte globulinCellular rejectionSPKT recipientsKidney allografts
2007
Clinical factors associated with graft fibrosis in kidney‐transplant recipients on steroid‐avoidance immunosuppression
Heilman RL, Chakkera HA, Reddy KS, Colby TV, Moss AA, Williams JW, Mazur MJ, Petrides S, Mulligan DC. Clinical factors associated with graft fibrosis in kidney‐transplant recipients on steroid‐avoidance immunosuppression. Clinical Transplantation 2007, 22: 309-315. PMID: 18482051, DOI: 10.1111/j.1399-0012.2007.00786.x.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsBiopsyCreatinineFemaleFibrosisHumansImmunosuppression TherapyKidneyKidney TransplantationMaleMiddle AgedMultivariate AnalysisPancreas TransplantationConceptsSteroid avoidance immunosuppressionKidney-pancreas transplant recipientsOne-year biopsyKidney transplant recipientsBK nephropathySerum creatinineProtocol biopsiesRecipient ageTransplant recipientsGraft fibrosisUnadjusted logistic regression analysisLower body mass indexMultivariate logistic regression modelCI scoresPrimary kidney transplantsPancreas transplant recipientsBody mass indexInterstitial cellular infiltrateLogistic regression analysisLogistic regression modelsAcute rejectionAntigen mismatchesAntithymocyte globulinGraft outcomeKidney transplant
1997
Intrathymic spleen cell inoculation and ALS fails to induce tolerance to rat pancreas allografts
Schulak JA, Mulligan DC, Robinson A. Intrathymic spleen cell inoculation and ALS fails to induce tolerance to rat pancreas allografts. Transplantation Proceedings 1997, 29: 1070-1071. PMID: 9123203, DOI: 10.1016/s0041-1345(96)00405-8.Peer-Reviewed Original ResearchAnimalsAntilymphocyte SerumGraft SurvivalHeart TransplantationHistocompatibility Antigens Class IHistocompatibility Antigens Class IIImmunosuppression TherapyLymphocyte TransfusionMajor Histocompatibility ComplexMalePancreas TransplantationRatsRats, Inbred BUFRats, Inbred LewSpleenThymus GlandTime FactorsTransplantation, Homologous