2003
Tacrolimus as a liver flush solution to ameliorate the effects of ischemia/reperfusion injury following liver transplantation
St. Peter SD, Post DJ, Rodriguez‐Davalos M, Douglas DD, Moss AA, Mulligan DC. Tacrolimus as a liver flush solution to ameliorate the effects of ischemia/reperfusion injury following liver transplantation. Liver Transplantation 2003, 9: 144-149. PMID: 12548508, DOI: 10.1053/jlts.2003.50018.Peer-Reviewed Original ResearchConceptsIschemia/reperfusion injuryTacrolimus treatmentReperfusion injuryFlush solutionGroup 2Group 1Partial thromboplastin time valuesBaseline aspartate aminotransferaseEarly graft functionOrthotopic liver transplantProspective randomized fashionTotal ischemia timeSerum laboratory valuesSuperior early graft functionGraft functionLiver transplantLiver transplantationHepatic allograftsHepatocellular injuryLiver injuryPlacebo treatmentLiver diseasePlasma-Lyte AHepatocellular damageIschemia time
2002
A randomized, prospective, double-blinded evaluation of selective bowel decontamination in liver transplantation
Hellinger WC, Yao JD, Alvarez S, Blair JE, Cawley JJ, Paya CV, O’Brien P, Spivey JR, Dickson RC, Harnois DM, Douglas DD, Hughes CB, Nguyen JH, Mulligan DC, Steers JL. A randomized, prospective, double-blinded evaluation of selective bowel decontamination in liver transplantation. Transplantation 2002, 73: 1904-1909. PMID: 12131685, DOI: 10.1097/00007890-200206270-00009.Peer-Reviewed Original ResearchConceptsSelective bowel decontaminationLiver transplantationRate of infectionDay 0Bowel decontaminationMedical careBacterial infectionsDouble-blinded fashionDouble-blinded evaluationGentamicin 80Mortal complicationsUncontrolled trialsSwab culturesTreatment groupsTransplantationPatientsDay 21Day 60Routine useInfectionPositive floraNegative floraFecal cultureCareDeath