2019
Frequency of whole-organ in lieu of split-liver transplantation over the last decade: Children experienced increased wait time and death
Valentino PL, Emre S, Geliang G, Li L, Deng Y, Mulligan D, Rodriguez-Davalos M. Frequency of whole-organ in lieu of split-liver transplantation over the last decade: Children experienced increased wait time and death. American Journal Of Transplantation 2019, 19: 3114-3123. PMID: 31152483, DOI: 10.1111/ajt.15481.Peer-Reviewed Original ResearchConceptsAdult recipientsTransplantation Network/United NetworkNumber of allograftsOrgan Sharing dataSplit-liver transplantationCareful patient selectionDeceased donor liversNumber of LTLT graftSLT recipientsUnderwent LTWLT recipientsPediatric candidatesPatient selectionDonor liversOrgan utilizationUnited NetworkOrgan shortageOrgan procurementSmall childrenRecipientsTransplantation
2016
A resilience intervention involving mindfulness training for transplant patients and their caregivers
Stonnington CM, Darby B, Santucci A, Mulligan P, Pathuis P, Cuc A, Hentz JG, Zhang N, Mulligan D, Sood A. A resilience intervention involving mindfulness training for transplant patients and their caregivers. Clinical Transplantation 2016, 30: 1466-1472. PMID: 27618687, DOI: 10.1111/ctr.12841.Peer-Reviewed Original ResearchConceptsTransplant patientsCell transplant patientsNegative affectNeuroscience of stressMindfulness-based stress reductionMindfulness-based interventionsStem cell transplant patientsHealth-related qualityKidney/pancreasMeasures of stressPositive affectMindfulness trainingResilience interventionsMindfulness practiceMonths postinterventionMayo ClinicCaregiver interventionsMental componentSolid organsPatientsStress reductionAffectCaregiversMost participantsAnxiety
2012
Endoscopic treatment of anastomotic biliary strictures after living donor liver transplantation: outcomes after maximal stent therapy
Hsieh TH, Mekeel KL, Crowell MD, Nguyen CC, Das A, Aqel BA, Carey EJ, Byrne TJ, Vargas HE, Douglas DD, Mulligan DC, Harrison ME. Endoscopic treatment of anastomotic biliary strictures after living donor liver transplantation: outcomes after maximal stent therapy. Gastrointestinal Endoscopy 2012, 77: 47-54. PMID: 23062758, DOI: 10.1016/j.gie.2012.08.034.Peer-Reviewed Original ResearchMeSH KeywordsAlanine TransaminaseAlkaline PhosphataseAspartate AminotransferasesBiliary Tract DiseasesBilirubinCholangiopancreatography, Endoscopic RetrogradeCholestasisEndoscopy, Digestive SystemFemaleFollow-Up StudiesHumansLiver TransplantationLiving DonorsMalePostoperative ComplicationsRecurrenceRetrospective StudiesStentsTreatment OutcomeConceptsLiving-donor liver transplantationAnastomotic biliary stricturesEndoscopic retrograde cholangiographyPercutaneous transhepatic cholangiographyBiliary stricturesEndoscopic therapyLiver transplantationEndoscopic treatmentRetrograde cholangiographySurgical revisionRetrospective studyTertiary care academic medical centerAggressive endoscopic approachStent placement strategyUnsuccessful endoscopic therapyDonor liver transplantationOptimal endoscopic treatmentAcademic medical centerDuct anastomosisInitial therapyBile leakageEndoscopic dilationBalloon dilationCommon complicationComplication rateLaparoscopic bilateral native nephrectomies with simultaneous kidney transplantation
Martin AD, Mekeel KL, Castle EP, Vaish SS, Martin GL, Moss AA, Mulligan DC, Heilman RL, Reddy KS, Andrews PE. Laparoscopic bilateral native nephrectomies with simultaneous kidney transplantation. BJU International 2012, 110: e1003-e1007. PMID: 22882539, DOI: 10.1111/j.1464-410x.2012.11379.x.Peer-Reviewed Original ResearchConceptsBilateral laparoscopic nephrectomyAutosomal dominant polycystic kidney diseaseSimultaneous kidney transplantationShorter total hospital stayBilateral native nephrectomyTotal hospital stayNative nephrectomyHospital stayKidney transplantationGraft functionRenal transplantPerioperative outcomesKidney transplantLaparoscopic approachSingle tertiary academic centerImmediate graft functionInvasive laparoscopic approachSimultaneous renal transplantMedian hospital stayTertiary academic centerTotal operative durationPolycystic kidney diseaseRenal transplantationComparable morbidityComplication rate
2010
Outcomes After Simultaneous Pancreas and Kidney Transplantation and the Discriminative Ability of the C-peptide Measurement Pretransplant Among Type 1 and Type 2 Diabetes Mellitus
Chakkera HA, Bodner JK, Heilman RL, Mulligan DC, Moss AA, Mekeel KL, Mazur MJ, Hamawi K, Ray RM, Beck GL, Reddy KS. Outcomes After Simultaneous Pancreas and Kidney Transplantation and the Discriminative Ability of the C-peptide Measurement Pretransplant Among Type 1 and Type 2 Diabetes Mellitus. Transplantation Proceedings 2010, 42: 2650-2652. PMID: 20832562, PMCID: PMC3060052, DOI: 10.1016/j.transproceed.2010.04.065.Peer-Reviewed Original ResearchMeSH KeywordsAdultC-PeptideCreatinineDiabetes Mellitus, Type 1Diabetes Mellitus, Type 2Diabetic NephropathiesDiabetic RetinopathyFemaleFollow-Up StudiesGlycated HemoglobinGraft RejectionHumansKidney Failure, ChronicKidney TransplantationMaleMiddle AgedPancreas TransplantationRetrospective StudiesSurvival AnalysisTissue DonorsConceptsEnd-stage renal diseaseType of diabetesC-peptideSimultaneous pancreasKidney transplantationPatient survivalGlutamic acid decarboxylase antibodiesType 2 diabetes mellitusDetectable C-peptideMean creatinine clearanceRenal Disease equationModification of DietBody mass indexC-peptide measurementsRegression survival analysisGlycosylate hemoglobinDiabetic ketoacidosisESRD patientsPancreas transplantationT2DM patientsCreatinine clearanceDecarboxylase antibodiesOral hypoglycemicsRenal replacementDiabetes mellitus
2009
Simultaneous Heart and Kidney Transplantation After Bridging With The CardioWest Total Artificial Heart
Jaroszewski DE, Pierce CC, Staley LL, Wong R, Scott RR, Steidley EE, Gopalan RS, DeValeria P, Lanza L, Mulligan D, Arabia FA. Simultaneous Heart and Kidney Transplantation After Bridging With The CardioWest Total Artificial Heart. The Annals Of Thoracic Surgery 2009, 88: 1324-1326. PMID: 19766830, DOI: 10.1016/j.athoracsur.2009.02.056.Peer-Reviewed Original ResearchConceptsCardioWest total artificial heartTotal artificial heartRenal failureEnd-stage renal failureTotal artificial heart implantationRisk of mortalityArtificial heart implantationArtificial heartSimultaneous heartCardiac transplantationKidney transplantationRelative contraindicationHeart implantationSuccessful treatmentTransplantationHeartContraindicationsPatientsFailureKidneyMortalityOutcomes of Simultaneous Kidney–Pancreas Transplantation With Positive Cross-Match
Heilman R, Chakkera H, Mazur M, Petrides S, Moss A, Mekeel K, Mulligan D, Reddy K. Outcomes of Simultaneous Kidney–Pancreas Transplantation With Positive Cross-Match. Transplantation Proceedings 2009, 41: 303-306. PMID: 19249540, DOI: 10.1016/j.transproceed.2008.08.154.Peer-Reviewed Original ResearchMeSH KeywordsAlemtuzumabAntibodies, MonoclonalAntibodies, Monoclonal, HumanizedAntibodies, NeoplasmAntilymphocyte SerumDrug Therapy, CombinationFollow-Up StudiesGraft SurvivalHistocompatibility TestingHumansImmunoglobulins, IntravenousImmunosuppressive AgentsKidney TransplantationPancreas TransplantationRetrospective StudiesSurvival AnalysisTime FactorsTreatment OutcomeConceptsAntibody-mediated rejectionLow-dose intravenous immunoglobulinAcute cellular rejectionIntravenous immunoglobulinStudy groupControl groupAllograft survivalMycophenolate mofetilRisk of AMRSimultaneous pancreas-kidney transplant recipientsPancreas-kidney transplant recipientsSimultaneous kidney-pancreas transplantationDose intravenous immunoglobulinKidney-pancreas transplantationPositive cross matchRabbit antithymocyte globulinActuarial patient survivalKidney allograft survivalKidney transplant recipientsPancreas allograft survivalAcute rejectionAntithymocyte globulinCellular rejectionSPKT recipientsKidney allografts
2007
Endoscopic treatment of anastomotic biliary strictures after deceased donor liver transplantation: outcomes after maximal stent therapy
Pasha SF, Harrison ME, Das A, Nguyen CC, Vargas HE, Balan V, Byrne TJ, Douglas DD, Mulligan DC. Endoscopic treatment of anastomotic biliary strictures after deceased donor liver transplantation: outcomes after maximal stent therapy. Gastrointestinal Endoscopy 2007, 66: 44-51. PMID: 17591473, DOI: 10.1016/j.gie.2007.02.017.Peer-Reviewed Original ResearchConceptsDeceased donor liver transplantationAnastomotic biliary stricturesDonor liver transplantationLiver transplantationEndoscopic therapyStent placementBiliary stricturesEndoscopic treatmentBiliary dilationEndoscopic dilationSurgical interventionTertiary care academic medical centerAggressive endoscopic approachAggressive endoscopic therapyBile duct patencyResolution of stricturesMultiple stent placementOptimal endoscopic treatmentAcademic medical centerPersistent resolutionProlonged therapyMedian durationBalloon dilationMajor complicationsRecurrent strictureDiffuse Parenchymal Urine Leak After Kidney Transplantation Following Degloving Injury During Donor Nephrectomy
Mekeel KL, Mazur MJ, Reddy KS, Mulligan DC, Heilman RL, Chakkera HA, Andrews PE, Moss AA. Diffuse Parenchymal Urine Leak After Kidney Transplantation Following Degloving Injury During Donor Nephrectomy. American Journal Of Transplantation 2007, 7: 2039-2041. PMID: 17578504, DOI: 10.1111/j.1600-6143.2007.01870.x.Peer-Reviewed Original ResearchConceptsDonor nephrectomyUrine leakRecipient graft functionGood renal functionLaparoscopic donor nephrectomyComplete deglovingGraft functionKidney transplantationPostoperative courseRenal functionPeritoneal windowLarge urinomaGlue treatmentKidneyUnconcentrated urineKidney surfaceNephrectomyLeakUrinomaPatientsTransplantationDeglovingInjuryTraumaUrine
2006
Living donor liver transplantation for hepatitis C‐related cirrhosis: No difference in histological recurrence when compared to deceased donor liver transplantation recipients
Guo L, Orrego M, Rodriguez‐Luna H, Balan V, Byrne T, Chopra K, Douglas DD, Harrison E, Moss A, Reddy KS, Williams JW, Rakela J, Mulligan D, Vargas HE. Living donor liver transplantation for hepatitis C‐related cirrhosis: No difference in histological recurrence when compared to deceased donor liver transplantation recipients. Liver Transplantation 2006, 12: 560-565. PMID: 16555313, DOI: 10.1002/lt.20660.Peer-Reviewed Original ResearchConceptsDeceased donor liver transplantationDonor liver transplantationLiver transplantationHistological recurrenceHepatitis CDeceased-donor liver transplantation (DDLT) recipientsEnd-stage liver disease (MELD) scoreDonor liver transplantation recipientsHepatitis C virus infectionKaplan-Meier survival analysisDetectable HCV RNAHistological recurrence rateC virus infectionGraft survival ratesLiver Disease scoreActivity of inflammationLiver transplantation recipientsStatistical differenceChild-TurcotteDDLT groupLDLT patientsPugh scoreRecurrent HCVLiver transplantYears posttransplantation
1997
Influence of steroid withdrawal on proteinuria in renal allograft recipients
Ghandour FZ, Knauss TC, Mulligan DC, Schulak JA, Hricik DE. Influence of steroid withdrawal on proteinuria in renal allograft recipients. Clinical Transplantation 1997, 11: 395-398. PMID: 9361929, DOI: 10.1111/j.1399-0012.1997.tb00840.x.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAnalysis of VarianceAnti-Inflammatory AgentsAzathioprineChi-Square DistributionChronic DiseaseCreatinineCyclosporineFemaleFollow-Up StudiesGlucocorticoidsGraft RejectionHumansImmunosuppressive AgentsKidney TransplantationLinear ModelsLogistic ModelsMaleMiddle AgedMultivariate AnalysisPrednisoneProteinuriaRecurrenceTransplantation, HomologousConceptsSteroid withdrawalUrinary protein excretionAllograft rejectionProtein excretionPrimary renal transplant recipientsAcute allograft rejectionRenal allograft recipientsRenal transplant recipientsChronic allograft rejectionSpot urine specimensAcute rejectionAllograft recipientsSteroid therapyTransplant recipientsClinical variablesUrine creatinineUrine specimensPatientsProteinuriaWithdrawalExcretionRecipientsRejectionCreatinineTransplantation
1995
Use of anti-hepatitis C virus seropositive organs in liver transplantation.
Mulligan DC, Goldstein RM, Crippin JS, Abouljoud MS, Levy MF, Husberg BS, Gonwa TA, Foster BR, Tillery GW, Klintmalm GB. Use of anti-hepatitis C virus seropositive organs in liver transplantation. Transplantation Proceedings 1995, 27: 1204-5. PMID: 7878850.Peer-Reviewed Original Research