2013
Tissue microarrays: leaping the gap between research and clinical adoption
Gustavson MD, Rimm DL, Dolled-Filhart M. Tissue microarrays: leaping the gap between research and clinical adoption. Personalized Medicine 2013, 10: 441-451. PMID: 29758838, DOI: 10.2217/pme.13.42.Peer-Reviewed Original ResearchTissue microarrayClinical laboratory settingUse of TMAsRoutine diagnostic purposesAdvanced imagingClinical settingPatient samplesDiagnostic useTissue assessmentTranslational research settingsExpression assessmentClinical research applicationsBiomarker analysisDiagnostic assaysDiagnostic purposesResearch settingsClinical adoption
2008
Quantitative Assessment of Tissue Biomarkers and Construction of a Model to Predict Outcome in Breast Cancer Using Multiple Imputation
Emerson JW, Dolled-Filhart M, Harris L, Rimm DL, Tuck DP. Quantitative Assessment of Tissue Biomarkers and Construction of a Model to Predict Outcome in Breast Cancer Using Multiple Imputation. Cancer Informatics 2008, 7: cin.s911. PMID: 19352457, PMCID: PMC2664700, DOI: 10.4137/cin.s911.Peer-Reviewed Original ResearchLymph node statusProtein expression levelsNode statusBreast cancerBaseline clinical modelCohort of patientsLack of tumorTissue microarray studyLarge independent cohortsExpression levelsMultiple imputationPatient survivalTraining cohortTissue biomarkersIndependent cohortClinical modelSelect markersCohortSimilar improvementsBiomarker analysisCancerClinical annotationProtein markersBiomarkersFuture studies