2019
Phenotyping tumor infiltrating lymphocytes (PhenoTIL) on H&E tissue images: predicting recurrence in lung cancer
Barrera C, Corredor G, Wang X, Schalper K, Rimm D, Velcheti V, Madabhushi A, Castro E. Phenotyping tumor infiltrating lymphocytes (PhenoTIL) on H&E tissue images: predicting recurrence in lung cancer. Progress In Biomedical Optics And Imaging 2019, 10956: 1095607-1095607-8. DOI: 10.1117/12.2513048.Peer-Reviewed Original ResearchTumor-infiltrating lymphocytesTIL densityLung cancerEarly stage non-small cell lung cancer patientsNon-small cell lung cancer patientsCell lung cancer patientsEarly-stage lung cancerKaplan-Meier analysisLung cancer patientsStage lung cancerLikelihood of recurrenceBetter prognosisLate recurrenceCancer patientsDifferent cancer typesDisease outcomeRecurrenceDifferent subtypesCancer typesLymphocytesCancerPatientsPrognosisIndependent validation
2015
The effect of BCG intravesical therapy and recurrence on PDL1 expression in non-invasive bladder cancers.
Hurwitz M, Adeniran A, Yao X, Hafez N, Schalper K, Rimm D, Petrylak D. The effect of BCG intravesical therapy and recurrence on PDL1 expression in non-invasive bladder cancers. Journal Of Clinical Oncology 2015, 33: e15504-e15504. DOI: 10.1200/jco.2015.33.15_suppl.e15504.Peer-Reviewed Original Research
2012
Validation of IHC4 algorithms for prediction of risk of recurrence in early breast cancer using both conventional and quantitative IHC approaches.
Christiansen J, Bartlett J, Gustavson M, Rimm D, Robson T, Van De Velde C, Hasenburg A, Kieback D, Putter H, Markopoulos C, Dirix L, Seynaeve C, Rea D. Validation of IHC4 algorithms for prediction of risk of recurrence in early breast cancer using both conventional and quantitative IHC approaches. Journal Of Clinical Oncology 2012, 30: 517-517. DOI: 10.1200/jco.2012.30.15_suppl.517.Peer-Reviewed Original ResearchEarly breast cancerBreast cancerDAB IHCHazard ratioDisease recurrenceCox proportional hazard modelingKaplan-Meier survival analysisCox proportional hazards modelC-index calculationClinical prognostic factorsProportional hazard modelingProportional hazards modelResidual riskHormone therapyIndependent predictorsPrognostic factorsPrediction of riskRisk markersClinical utilityHazards modelRecurrence riskRecurrencePathology studiesSurvival analysisMultivariate analysis