2019
An Evidence-Based Guideline Supporting Restricted Opioid Prescription after Pediatric Appendectomy
Freedman-Weiss MR, Chiu AS, Worhunsky D, Manchisi A, Torres-Maldonado I, Sagnella L, Caty MG, Cowles RA, Ozgediz DE, Christison-Lagay ER, Solomon DG, Stitelman DH. An Evidence-Based Guideline Supporting Restricted Opioid Prescription after Pediatric Appendectomy. Journal Of Pediatric Surgery 2019, 55: 106-111. PMID: 31699433, DOI: 10.1016/j.jpedsurg.2019.09.063.Peer-Reviewed Original ResearchConceptsLaparoscopic appendectomyOpioid prescriptionsPostoperative opioid needsPostoperative telephone interviewsQuantity of opioidsPresence of painYoung adult patientsEvidence-based guidelinesMain outcome measuresOpioid needsAnalgesic useModifiable contributorPain reliefAdequate analgesiaAdult patientsChart reviewHospital dischargeMost patientsPatients 5Pediatric appendectomyYounger patientsPain concernsAverage MMEOpioid epidemicOutcome measures
2018
Opioid Prescribing Habits of General Versus Pediatric Surgeons After Uncomplicated Laparoscopic Appendectomy
Freedman-Weiss MR, Chiu A, Solomon DG, Christison-Lagay ER, Ozgediz DE, Cowles RA, Caty MG, Stitelman DH. Opioid Prescribing Habits of General Versus Pediatric Surgeons After Uncomplicated Laparoscopic Appendectomy. Journal Of Surgical Research 2018, 235: 404-409. PMID: 30691822, DOI: 10.1016/j.jss.2018.09.085.Peer-Reviewed Original ResearchConceptsOral morphine equivalentsUncomplicated laparoscopic appendectomyAmount of opioidsLaparoscopic appendectomyGeneral surgeonsPediatric surgeonsSurgery providersFuture drug abuseOpioid prescribing habitsPills of oxycodoneRetrospective chart reviewYoung adult patientsPrimary outcome measureType of analgesiaGeneral surgery servicePediatric laparoscopic appendectomyHigh-risk populationLength of stayCommon surgical procedureSingle health systemAge group 13More opioidsMorphine equivalentsModifiable contributorOpioid analgesiaRoutine postnatal chest x-ray and intensive care admission are unnecessary for a majority of infants with congenital lung malformations
Greig CJ, Keiser AM, Cleary MA, Stitelman DH, Christison-Lagay ER, Ozgediz DE, Solomon DG, Caty MG, Cowles RA. Routine postnatal chest x-ray and intensive care admission are unnecessary for a majority of infants with congenital lung malformations. Journal Of Pediatric Surgery 2018, 54: 670-674. PMID: 30503193, DOI: 10.1016/j.jpedsurg.2018.10.063.Peer-Reviewed Original ResearchConceptsAbnormal chest X-rayCongenital lung malformationsChest X-rayNICU admissionMajority of infantsRespiratory supportBirth weightGestational ageLung malformationsOdds ratioInitial symptomsNeonatal intensive care unit admissionInitial chest X-rayIntensive care unit admissionCare unit admissionIntensive care admissionLevel II evidenceDays of dischargeMajority of casesNICU stayROC cutoffUnit admissionCare admissionFuture care needsImmediate surgery
2010
Robust In Vivo Transduction of Nervous System and Neural Stem Cells by Early Gestational Intra Amniotic Gene Transfer Using Lentiviral Vector
Stitelman DH, Endo M, Bora A, Muvarak N, Zoltick PW, Flake AW, Brazelton TR. Robust In Vivo Transduction of Nervous System and Neural Stem Cells by Early Gestational Intra Amniotic Gene Transfer Using Lentiviral Vector. Molecular Therapy 2010, 18: 1615-1623. PMID: 20571539, PMCID: PMC2956924, DOI: 10.1038/mt.2010.125.Peer-Reviewed Original ResearchConceptsNeural stem cellsAdult neural stem cellsCell typesGene transferStem cellsGreen fluorescent protein marker geneProtein marker geneNervous system developmentNeural cell typesMajor neural cell typesLentiviral vectorsNeural cell populationsMajor cell typesAdult nervous systemGene functionMarker genesEmbryonic day 8Subventricular zoneEntire nervous systemNervous systemVivo transductionCell populationsFuture clinical applicationsGenetic disordersNeural groove