2023
Head and neck follicular lymphoma with marginal zone differentiation and BCL2 translocation t(14;18) in both nodular and extranodular sites: a case report with mini-review
Vageli D, Doukas P, Batrakouli O, Tsangari V, Zacharouli K, Pouliou E, Tzika S, Ioannou M. Head and neck follicular lymphoma with marginal zone differentiation and BCL2 translocation t(14;18) in both nodular and extranodular sites: a case report with mini-review. Oral Surgery Oral Medicine Oral Pathology And Oral Radiology 2023, 136: e139-e148. PMID: 37516620, DOI: 10.1016/j.oooo.2023.05.005.Peer-Reviewed Original ResearchMeSH KeywordsAgedBone MarrowCell DifferentiationFemaleHumansLymphoma, FollicularProto-Oncogene Proteins c-bcl-2Translocation, GeneticConceptsFollicular lymphomaMarginal zone differentiationGerminal centersB cellsParotid glandFollicular dendritic cell markersSame B-cell cloneBCL2 translocationDendritic cell markersBone marrow biopsyProliferative B cellsB cell clonesBCL2/IGHCase reportRare caseCell markersZone differentiationLymphomaParotidBCL6GlandDifferentiated cellsHeadDifferentiationMolecular analysis
2021
Pepsin Promotes Activation of Epidermal Growth Factor Receptor and Downstream Oncogenic Pathways, at Slightly Acidic and Neutral pH, in Exposed Hypopharyngeal Cells
Doukas PG, Vageli DP, Sasaki CT, Judson BL. Pepsin Promotes Activation of Epidermal Growth Factor Receptor and Downstream Oncogenic Pathways, at Slightly Acidic and Neutral pH, in Exposed Hypopharyngeal Cells. International Journal Of Molecular Sciences 2021, 22: 4275. PMID: 33924087, PMCID: PMC8074291, DOI: 10.3390/ijms22084275.Peer-Reviewed Original ResearchConceptsRelated-signaling pathwaysOncogenic pathwaysLaryngopharyngeal reflux diseaseEpidermal growth factor receptorSpecific oncogenic pathwaysDownstream oncogenic pathwaysGrowth factor receptorHypopharyngeal cellsReflux diseaseRisk factorsTherapeutic approachesIntermittent exposureTumorigenic effectsPronounced activationOncogenic factorSignificant upregulationFactor receptorSTAT3 activationAcidic pepsinEGFR activationCell viabilityPromotes ActivationActivationPrimary cellsCells