2023
Tumor treatment by pHLIP-targeted antigen delivery
DuPont M, Visca H, Moshnikova A, Engelman D, Reshetnyak Y, Andreev O. Tumor treatment by pHLIP-targeted antigen delivery. Frontiers In Bioengineering And Biotechnology 2023, 10: 1082290. PMID: 36686229, PMCID: PMC9853002, DOI: 10.3389/fbioe.2022.1082290.Peer-Reviewed Original ResearchAnti-HA antibodiesAntigen deliveryHigh titersTumor cellsTriple-negative breast tumorsCancer cellsDifferent vaccination schemesNegative breast tumorsHA epitopeAntigen therapyImmunized miceImmune cellsNeo-antigensT cellsSignificant tumorsVaccination schemeViral infectionTherapeutic efficacyBreast tumorsHepatic clearanceImmune systemMelanoma tumorsTumorsPeptide epitopesAdjuvant
2022
Targeting bladder urothelial carcinoma with pHLIP-ICG and inhibition of urothelial cancer cell proliferation by pHLIP-amanitin
Moshnikova A, Golijanin B, Amin A, Doyle J, Kott O, Gershman B, DuPont M, Li Y, Lu X, Engelman D, Andreev O, Reshetnyak Y, Golijanin D. Targeting bladder urothelial carcinoma with pHLIP-ICG and inhibition of urothelial cancer cell proliferation by pHLIP-amanitin. Frontiers In Urology 2022, 2: 868919. PMID: 36439552, PMCID: PMC9691284, DOI: 10.3389/fruro.2022.868919.Peer-Reviewed Original ResearchWhite light cystoscopyCancer cell proliferationUrothelial cancer cellsMalignant lesionsUrothelial cancerBladder cancerCancer cellsSuperficial bladder cancerLaparoscopic radical cystectomyBladder urothelial carcinomaCell proliferationHr of treatmentRadical cystectomyIntravesical instillationBladder specimensUrothelial carcinomaUseful biomarkerNIRF imagingHuman bladderSitu casesDifferent subtypesHistopathological processingCystoscopyTumor cellsCancer