Conversion of Phospholamban into a Soluble Pentameric Helical Bundle †
Li H, Cocco M, Steitz T, Engelman D. Conversion of Phospholamban into a Soluble Pentameric Helical Bundle †. Biochemistry 2001, 40: 6636-6645. PMID: 11380258, DOI: 10.1021/bi0026573.Peer-Reviewed Original ResearchConceptsMembrane proteinsLipid-exposed surfaceMembrane protein phospholambanLaser lightX-ray scatteringTransmembrane domainHelical bundleWild-type phospholambanOligomeric stateNative phospholambanPolar residuesSimilar foldHydrophobic residuesSoluble proteinReticulum membraneSmall-angle X-ray scatteringHelical pentamersProtein phospholambanSoluble variantProteinNatural proteinsNMR experimentsNative contactsMultiangle laser lightSarcoplasmic reticulum membranes