2022
Design and Implementation of a Culturally-Tailored Randomized Pilot Trial: Puerto Rican Optimized Mediterranean-Like Diet
Mattei J, Díaz-Alvarez C, Alfonso C, O’Neill H, Ríos-Bedoya C, Malik V, Godoy-Vitorino F, Cheng C, Spiegelman D, Willett W, Hu F, Rodríguez-Orengo J. Design and Implementation of a Culturally-Tailored Randomized Pilot Trial: Puerto Rican Optimized Mediterranean-Like Diet. Current Developments In Nutrition 2022, 7: 100022. PMID: 37181130, PMCID: PMC10100940, DOI: 10.1016/j.cdnut.2022.100022.Peer-Reviewed Original ResearchMediterranean-like dietNutritional counseling sessionsPilot trialHealthier cardiometabolic profileIndividual cardiometabolic factorsCardiometabolic risk factorsRandomized pilot trialDisease prevention programsCounseling sessionsDaily text messagesFree-living adultsCardiometabolic factorsCardiometabolic profileCardiometabolic healthSecondary outcomesPrimary outcomeRisk factorsDietary intakeIntervention groupChronic diseasesTwo-armOutcome measuresHigh riskMediterranean dietPsychosocial factors
2021
Workplace cafeteria and other multicomponent interventions to promote healthy eating among adults: A systematic review
Naicker A, Shrestha A, Joshi C, Willett W, Spiegelman D. Workplace cafeteria and other multicomponent interventions to promote healthy eating among adults: A systematic review. Preventive Medicine Reports 2021, 22: 101333. PMID: 33732606, PMCID: PMC7937753, DOI: 10.1016/j.pmedr.2021.101333.Peer-Reviewed Original ResearchMulticomponent interventionHealthy eatingWorkplace cafeteriasDietary intakeWorkplace health interventionsEnglish-language articlesImproved health outcomesFood choicesHealth risksWeb of ScienceCOM-B systemHealth risk indicatorsVegetable intakeHigh intakeElectronic searchHealth outcomesSystematic reviewHealth interventionsNarrative summaryReview protocolIntakeInterventionCafeteria interventionsRisk indicatorsBehavioral changes
2020
The Association of Cooking Fuel Use, Dietary Intake, and Blood Pressure among Rural Women in China
Bellows AL, Spiegelman D, Du S, Jaacks LM. The Association of Cooking Fuel Use, Dietary Intake, and Blood Pressure among Rural Women in China. International Journal Of Environmental Research And Public Health 2020, 17: 5516. PMID: 32751678, PMCID: PMC7432946, DOI: 10.3390/ijerph17155516.Peer-Reviewed Original ResearchConceptsBlood pressureHigh blood pressureHousehold air pollutionDietary intakeDiastolic blood pressureSystolic blood pressureRole of dietYears of ageFatty acid-rich foodsNonpregnant womenSolid fuel useLinear mixed effects modelsSolid cooking fuelsAdverse effectsIntakeWomenMixed effects modelsPossible mediationLower ratesCooking fuel useEffects modelRural womenCooking fuelAssociationDiet
2018
Cashew Nut Consumption Increases HDL Cholesterol and Reduces Systolic Blood Pressure in Asian Indians with Type 2 Diabetes: A 12-Week Randomized Controlled Trial
Mohan V, Gayathri R, Jaacks LM, Lakshmipriya N, Anjana RM, Spiegelman D, Jeevan RG, Balasubramaniam KK, Shobana S, Jayanthan M, Gopinath V, Divya S, Kavitha V, Vijayalakshmi P, Bai R M, Unnikrishnan R, Sudha V, Krishnaswamy K, Salas-Salvadó J, Willett WC. Cashew Nut Consumption Increases HDL Cholesterol and Reduces Systolic Blood Pressure in Asian Indians with Type 2 Diabetes: A 12-Week Randomized Controlled Trial. Journal Of Nutrition 2018, 148: 63-69. PMID: 29378038, DOI: 10.1093/jn/nxx001.Peer-Reviewed Original ResearchConceptsSystolic blood pressureBlood pressureNut consumptionBody weightAsian IndiansHDL cholesterolDiabetic dietNut supplementationSelf-reported dietary intakeStandard diabetic dietClinical Trials RegistryHDL cholesterol concentrationsPlasma HDL cholesterolType 2 diabetesCashew nut consumptionBlood lipidsControlled TrialsTrials RegistryGlycemic variablesLipid variablesDietary intakeIntervention groupLipid profileCardiovascular diseaseRobust variance estimation
2013
Dietary Patterns, Nutrient Intake, and Sociodemographic Characteristics in HIV-Infected Tanzanian Pregnant Women
Lukmanji Z, Hertzmark E, Spiegleman D, Fawzi WW. Dietary Patterns, Nutrient Intake, and Sociodemographic Characteristics in HIV-Infected Tanzanian Pregnant Women. Ecology Of Food And Nutrition 2013, 52: 34-62. PMID: 23282190, DOI: 10.1080/03670244.2012.705768.Peer-Reviewed Original ResearchConceptsPregnant womenNutrient intakeTanzanian pregnant womenWorld Health Organization recommendationsDietary macronutrient intakeLongitudinal clinical trialsVitamin supplementationClinical trialsDietary intakeMacronutrient intakeDietary patternsDiet intakeFood composition tablesHigh riskWomen's ageSociodemographic characteristicsIntakeInadequate foodDar es SalaamWomenHIVTwo-thirdsEducation levelComposition tablesAge
2009
Evaluation of a novel food composition database that includes glutamine and other amino acids derived from gene sequencing data
Lenders CM, Liu S, Wilmore DW, Sampson L, Dougherty LW, Spiegelman D, Willett WC. Evaluation of a novel food composition database that includes glutamine and other amino acids derived from gene sequencing data. European Journal Of Clinical Nutrition 2009, 63: 1433-1439. PMID: 19756030, PMCID: PMC3249386, DOI: 10.1038/ejcn.2009.110.Peer-Reviewed Original ResearchConceptsFood frequency questionnaireGlutamine intakeItem food frequency questionnaireEnergy-adjusted intakesContent of glutamineGene sequencing methodsMajor food proteinsGlutamine contentFrequency questionnaireDietary intakeHealth StudyAbsolute intakeNHS participantsFood composition databasesIntakeVs 4.4Person coefficientPearson correlation coefficientTotal proteinAmino acidsComposition databaseCorrelation coefficientFood proteinsSequencing methodsGlutamine consumption
2005
Predictors of Bone Mineral Density in Human Immunodeficiency Virus‐1 Infected Children
Jacobson DL, Spiegelman D, Duggan C, Weinberg GA, Bechard L, Furuta L, Nicchitta J, Gorbach SL, Miller TL. Predictors of Bone Mineral Density in Human Immunodeficiency Virus‐1 Infected Children. Journal Of Pediatric Gastroenterology And Nutrition 2005, 41: 339-346. PMID: 16131991, DOI: 10.1097/01.mpg.0000174468.75219.30.Peer-Reviewed Original ResearchMeSH KeywordsAbsorptiometry, PhotonAntiretroviral Therapy, Highly ActiveBlack or African AmericanBody CompositionBody HeightBody Mass IndexBody WeightBone DensityCase-Control StudiesChildChild DevelopmentCross-Sectional StudiesFemaleHispanic or LatinoHIV InfectionsHIV-1HumansLongitudinal StudiesMalePredictive Value of TestsProspective StudiesSeverity of Illness IndexVitaminsWhite PeopleConceptsBMD Z-scoresBone mineral densityLower BMD Z-scoresMineral densityZ-scorePopulation normsMultivitamin useDietary intakePredictors of BMDTotal body bone mineral densityLower weight z-scoreBody bone mineral densityLow bone mineral densitySibling controlsBetter bone mineral densityDual-energy X-ray absorptiometry (DXA) examinationDual-energy X-ray absorptiometryLower height Z-scoresHuman immunodeficiency virus-1Energy X-ray absorptiometryAdvanced HIV stageAge-adjusted percentileIndependent risk factorGender-adjusted z-scoresWeight z-scoreDietary intake in human immunodeficiency virus–infected adults: A comparison of dietary assessment methods
Hendricks K, Tang A, Spiegelman D, Skinner S, Woods M. Dietary intake in human immunodeficiency virus–infected adults: A comparison of dietary assessment methods. Journal Of The Academy Of Nutrition And Dietetics 2005, 105: 532-540. PMID: 15800553, DOI: 10.1016/j.jada.2005.01.028.Peer-Reviewed Original ResearchMeSH KeywordsAdultCohort StudiesDietDiet RecordsDiet SurveysDietary CarbohydratesDietary FatsDietary ProteinsEatingEnergy IntakeEthnicityFemaleHIV InfectionsHumansLongitudinal StudiesMaleMicronutrientsNutrition AssessmentNutrition PolicyRegression AnalysisReproducibility of ResultsSensitivity and SpecificitySurveys and QuestionnairesConceptsFood frequency questionnaireFood recordsDietary Reference IntakesCohort studyDietary intakeLarge cohortReference IntakesIntake dataHuman immunodeficiency virus-infected adultsNutrient intakeHuman immunodeficiency virus (HIV) infectionBlock Food Frequency QuestionnaireImmunodeficiency virus infectionHIV-positive participantsQuintile rankingsLongitudinal cohort studyMean percent agreementOngoing cohort studyProportion of subjectsDietary intake dataDietary assessment methodsNutrient intake dataEstimated nutrient intakeNutrient intake estimatesFrequency questionnairePregnancy Increases BMI in Adolescents of a Population-Based Birth Cohort 1 2
Fawzi W, Msamanga G, Spiegelman D, Hunter DJ. Pregnancy Increases BMI in Adolescents of a Population-Based Birth Cohort 1 2. Journal Of Nutrition 2005, 135: 938-944. PMID: 15795466, DOI: 10.1093/jn/135.4.938.Peer-Reviewed Original ResearchConceptsAntiretroviral therapyMultivitamin supplementsPregnant womenHIV-negative pregnant womenDaily multivitamin supplementEarly childhood infectionsAdverse pregnancy outcomesHIV disease progressionHIV-1 infectionAdequate dietary intakeEfficacy of vitaminAdverse health outcomesFurther studiesLow-cost interventionMo of ageUninfected childrenHIV diseasePregnancy outcomesPregnant HIVHIV infectionChildhood infectionsRandomized trialsNutritional interventionDietary intakeDisease progression
2004
Dairy Foods, Calcium, and Colorectal Cancer: A Pooled Analysis of 10 Cohort Studies
Cho E, Smith-Warner SA, Spiegelman D, Beeson WL, van den Brandt PA, Colditz GA, Folsom AR, Fraser GE, Freudenheim JL, Giovannucci E, Goldbohm RA, Graham S, Miller AB, Pietinen P, Potter JD, Rohan TE, Terry P, Toniolo P, Virtanen MJ, Willett WC, Wolk A, Wu K, Yaun SS, Zeleniuch-Jacquotte A, Hunter DJ. Dairy Foods, Calcium, and Colorectal Cancer: A Pooled Analysis of 10 Cohort Studies. Journal Of The National Cancer Institute 2004, 96: 1015-1022. PMID: 15240785, DOI: 10.1093/jnci/djh185.Peer-Reviewed Original ResearchMeSH KeywordsAdenomaAdultAgedAnimalsCalcium, DietaryCohort StudiesColorectal NeoplasmsDairy ProductsEatingEuropeFemaleHumansIncidenceMaleMiddle AgedMilkMultivariate AnalysisProportional Hazards ModelsProspective StudiesResearch DesignRisk AssessmentRisk FactorsSurveys and QuestionnairesUnited StatesConceptsColorectal cancerRelative riskMilk intakeCalcium intakeCohort studyPooled multivariable relative risksMultivariable relative risksFood frequency questionnaireColorectal cancer riskUsual dietary intakeConfidence intervalsDairy foodsFrequency questionnaireIncident casesDietary calciumPooled analysisLowest quintileInverse associationDietary intakeDistal colonEpidemiologic studiesCancer riskLower riskTotal calciumCancerDiet and risk of ischemic heart disease in India
Rastogi T, Reddy KS, Vaz M, Spiegelman D, Prabhakaran D, Willett WC, Stampfer MJ, Ascherio A. Diet and risk of ischemic heart disease in India. American Journal Of Clinical Nutrition 2004, 79: 582-592. PMID: 15051601, DOI: 10.1093/ajcn/79.4.582.Peer-Reviewed Original ResearchConceptsIschemic heart diseaseServings/wkIHD riskLower riskHeart diseaseInverse associationHospital-based case-control studyDose-dependent inverse associationLong-term dietary intakeFood frequency questionnaireAcute myocardial infarctionCase-control studyConditional logistic regressionPredictors of riskLower relative riskAlpha-linolenic acidBasis of ageMustard oilGreen leafy vegetablesMyocardial infarctionVegetable intakeLeading causeDietary intakeCereal intakeRelative risk
2003
Prospective study of the association of changes in dietary intake, physical activity, alcohol consumption, and smoking with 9-y gain in waist circumference among 16 587 US men
Koh-Banerjee P, Chu NF, Spiegelman D, Rosner B, Colditz G, Willett W, Rimm E. Prospective study of the association of changes in dietary intake, physical activity, alcohol consumption, and smoking with 9-y gain in waist circumference among 16 587 US men. American Journal Of Clinical Nutrition 2003, 78: 719-727. PMID: 14522729, DOI: 10.1093/ajcn/78.4.719.Peer-Reviewed Original ResearchConceptsWaist gainMetabolic equivalent taskWaist circumferenceAssociation of changesPhysical activityUS menAlcohol consumptionLifestyle factorsTrans fatsBody mass indexFiber/dVigorous physical activityAbdominal adipose tissueAbdominal obesityProspective cohortMass indexProspective studySmoking cessationProspective dataChronic diseasesDietary intakeSelf-report questionnairesAdipose tissueFiber consumptionEnergy intakeHigh-fiber diet in HIV-positive men is associated with lower risk of developing fat deposition
Hendricks KM, Dong KR, Tang AM, Ding B, Spiegelman D, Woods MN, Wanke CA. High-fiber diet in HIV-positive men is associated with lower risk of developing fat deposition. American Journal Of Clinical Nutrition 2003, 78: 790-795. PMID: 14522738, DOI: 10.1093/ajcn/78.4.790.Peer-Reviewed Original ResearchConceptsHIV-positive patientsFat depositionFood recordsDietary fiberHealthy Living cohortPast dietary intakeHIV-positive menCase-control studyOverall energy intakeWilcoxon rank sum testHigh-fiber dietRank sum testLiving cohortCurrent smokersDietary intakeResistance trainingLower riskEnergy intakePatientsUnhealthy behaviorsHealthy lifestyleHIVDietary componentsGreater intakeHigh-quality dietDietary carotenoids and risk of coronary artery disease in women 1 , 2 , 3
Osganian SK, Stampfer MJ, Rimm E, Spiegelman D, Manson JE, Willett WC. Dietary carotenoids and risk of coronary artery disease in women 1 , 2 , 3. American Journal Of Clinical Nutrition 2003, 77: 1390-1399. PMID: 12791615, DOI: 10.1093/ajcn/77.6.1390.Peer-Reviewed Original ResearchConceptsRisk of CADCoronary artery diseaseArtery diseaseHigh intakePrevention of CADIncident coronary artery diseaseSemiquantitative food frequency questionnaireCAD risk factorsBeta-carotene supplementationFood frequency questionnaireCurrent smoking statusDietary carotenoidsSignificant inverse associationLutein/zeaxanthinHigh blood concentrationsConsumption of carotenoidsCAD riskSmoking statusIncident casesHighest quintileLowest quintileInverse associationRisk factorsDietary intakeBlood concentrations
2002
Mercury and the Risk of Coronary Heart Disease in Men
Yoshizawa K, Rimm EB, Morris JS, Spate VL, Hsieh CC, Spiegelman D, Stampfer MJ, Willett WC. Mercury and the Risk of Coronary Heart Disease in Men. New England Journal Of Medicine 2002, 347: 1755-1760. PMID: 12456851, DOI: 10.1056/nejmoa021437.Peer-Reviewed Original ResearchConceptsCoronary heart diseaseHeart diseaseMale health professionalsHigh dietary intakeYears of ageCase-control designMercury levelsSmoking statusTotal mercury exposureControl subjectsLowest quintileRisk factorsDietary intakeCardiovascular diseaseRelative riskCohort membersPrevious historyToenail clippingsHealth professionalsDiseaseConsumption of fishMercury exposureMean mercury levelRiskFish consumptionIndividual carotenoid concentrations in adipose tissue and plasma as biomarkers of dietary intake 1 , 2 , 3
El-Sohemy A, Baylin A, Kabagambe E, Ascherio A, Spiegelman D, Campos H. Individual carotenoid concentrations in adipose tissue and plasma as biomarkers of dietary intake 1 , 2 , 3. American Journal Of Clinical Nutrition 2002, 76: 172-179. PMID: 12081831, DOI: 10.1093/ajcn/76.1.172.Peer-Reviewed Original ResearchConceptsAdipose tissuePartial Spearman correlation coefficientsFood frequency questionnaireBiomarkers of intakeBody mass indexTotal energy intakeVLDL-cholesterol concentrationsMajor dietary carotenoidsLong-term intakeTissue biopsy samplesIndividual carotenoid concentrationsDietary interviewSpearman correlation coefficientMass indexAdipose tissue biopsy samplesDietary intakePlasma concentrationsCarotenoid intakeBlood samplesBiopsy samplesPlasma carotenoidsTissue carotenoid concentrationsEnergy intakeIntakeDietary carotenoidsVitamins and carotenoids intake and the risk of basal cell carcinoma of the skin in women (United States)
Fung TT, Hunter DJ, Spiegelman D, Colditz GA, Speizer FE, Willett WC. Vitamins and carotenoids intake and the risk of basal cell carcinoma of the skin in women (United States). Cancer Causes & Control 2002, 13: 221-230. PMID: 12020103, DOI: 10.1023/a:1015036317596.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge DistributionAscorbic AcidCarcinoma, Basal CellCarotenoidsCohort StudiesConfidence IntervalsDietDietary SupplementsFemaleHumansIncidenceLogistic ModelsMiddle AgedProbabilityProspective StudiesRisk AssessmentSensitivity and SpecificitySkin NeoplasmsUnited StatesVitamin AVitamin EVitaminsConceptsBasal cell carcinomaVitamin ACell carcinomaDietary intakeRelative riskSun sensitivity factorsMultivariate relative riskFood frequency questionnaireRisk of BCCSignificant inverse associationIncidence of BCCImportant protective roleFirst diagnosisDietary factorsInverse associationSun exposureLatency periodProtective roleSpecific carotenoidsLogistic regressionVitamin CBottom quintileIntakeCarcinomaRiskDietary and Adipose Tissue Gamma-Tocopherol and Risk of Myocardial Infarction
El-Sohemy A, Baylin A, Spiegelman D, Ascherio A, Campos H. Dietary and Adipose Tissue Gamma-Tocopherol and Risk of Myocardial Infarction. Epidemiology 2002, 13: 216-223. PMID: 11880764, DOI: 10.1097/00001648-200203000-00018.Peer-Reviewed Original ResearchConceptsDietary vitamin EMyocardial infarctionGamma-tocopherolOdds ratioVitamin ENonfatal myocardial infarctionFood frequency questionnaireCoronary heart diseasePopulation-based studyFirst myocardial infarctionConfidence intervalsConditional logistic regressionAdipose tissue samplesHighest quintileSupplement usersLowest quintileHeart diseaseInverse associationDietary intakeLower riskSubstantial inverse associationMultivariate analysisLogistic regressionTissue samplesWeak associationNutrient intake and body weight in a large HIV cohort that includes women and minorities
WOODS MN, SPIEGELMAN D, Knox TA, FORRESTER JE, CONNORS JL, SKINNER SC, Silva M, KIM JH, GORBACH SL. Nutrient intake and body weight in a large HIV cohort that includes women and minorities. Journal Of The Academy Of Nutrition And Dietetics 2002, 102: 203-211. PMID: 11846114, DOI: 10.1016/s0002-8223(02)90049-0.Peer-Reviewed Original ResearchConceptsVitamin/mineral supplementsNutrient intakeMicronutrient intakeBaseline nutrient intakeLarge HIV cohortCD4 cell countCD4 lymphocyte countHIV-positive populationBody mass indexInadequate nutrient intakeStudy sampleNHANES III dataWilcoxon rank sum testCubic spline modelsMineral supplementsRank sum testHIV cohortLymphocyte countSpearman correlation coefficientMass indexProspective studyFood recordsMedian intakeDietary intakeNutritional intake
2001
Application of the Method of Triads to Evaluate the Performance of Food Frequency Questionnaires and Biomarkers as Indicators of Long-term Dietary Intake
Kabagambe EK, Baylin A, Allan DA, Siles X, Spiegelman D, Campos H. Application of the Method of Triads to Evaluate the Performance of Food Frequency Questionnaires and Biomarkers as Indicators of Long-term Dietary Intake. American Journal Of Epidemiology 2001, 154: 1126-1135. PMID: 11744518, DOI: 10.1093/aje/154.12.1126.Peer-Reviewed Original ResearchMeSH KeywordsAdipose TissueBiomarkersCarotenoidsCosta RicaEpidemiologic Research DesignFactor Analysis, StatisticalFatty AcidsFatty Acids, UnsaturatedFemaleHumansLycopeneMaleMental RecallMiddle AgedMinority GroupsNutrition SurveysReproducibility of ResultsSensitivity and SpecificitySurveys and QuestionnairesTime FactorsTocopherolsConceptsFood frequency questionnaireDietary intakeMethod of triadsFrequency questionnaireDietary recallsAdipose tissueLong-term dietary intakeFatty acidsUS minority groupsSuperior biomarkerPoor biomarkerTissue samplesBiomarkersIntakeMedian validity coefficientsTissueValidity coefficientsQuestionnaireSubjectsPast yearPlasmaTocopherolsWomen