2004
Fruit and Vegetable Intake and Risk of Major Chronic Disease
Hung HC, Joshipura KJ, Jiang R, Hu FB, Hunter D, Smith-Warner SA, Colditz GA, Rosner B, Spiegelman D, Willett WC. Fruit and Vegetable Intake and Risk of Major Chronic Disease. Journal Of The National Cancer Institute 2004, 96: 1577-1584. PMID: 15523086, DOI: 10.1093/jnci/djh296.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAnalysis of VarianceCardiovascular DiseasesCause of DeathChronic DiseaseConfidence IntervalsConfounding Factors, EpidemiologicDiet SurveysFeeding BehaviorFemaleFollow-Up StudiesFruitHealth PersonnelHumansIncidenceMaleMiddle AgedNeoplasmsProportional Hazards ModelsProspective StudiesResearch DesignRisk AssessmentRisk FactorsSurveys and QuestionnairesUnited StatesVegetablesConceptsMajor chronic diseasesVegetable intakeCardiovascular diseaseChronic diseasesRelative riskHealth StudyVegetable consumptionGreen leafy vegetable intakeSemiquantitative food frequency questionnaireCox proportional hazards analysisOverall cancer incidenceTotal fruitNurses' Health StudyFood frequency questionnaireProportional hazards analysisStrong inverse associationProspective cohortGreen leafy vegetablesHighest quintileInverse associationCancer incidenceFood groupsHealth professionalsOverall healthDietary information
2003
Vitamin C and risk of coronary heart disease in women
Osganian SK, Stampfer MJ, Rimm E, Spiegelman D, Hu FB, Manson JE, Willett WC. Vitamin C and risk of coronary heart disease in women. Journal Of The American College Of Cardiology 2003, 42: 246-252. PMID: 12875759, DOI: 10.1016/s0735-1097(03)00575-8.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge FactorsAntioxidantsAscorbic AcidChemopreventionCoronary DiseaseDiabetes ComplicationsDietary SupplementsFemaleHumansHypercholesterolemiaHypertensionIncidenceLife StyleLogistic ModelsMiddle AgedMultivariate AnalysisNutrition SurveysProportional Hazards ModelsProspective StudiesRisk FactorsSmokingSurveys and QuestionnairesUnited StatesWomen's HealthConceptsRisk of CHDCoronary heart diseaseVitamin C intakeCoronary risk factorsVitamin C supplementsC intakeVitamin CC supplementsHeart diseaseRisk factorsLower riskDetailed semiquantitative food frequency questionnaireIncidence of CHDVitamin C supplement useIncident coronary heart diseaseSemiquantitative food frequency questionnaireFood frequency questionnaireSignificant inverse associationIncident casesSupplement useProspective InvestigationInverse associationProtective associationFemale nursesTotal intakeDietary carotenoids and risk of coronary artery disease in women 1 , 2 , 3
Osganian SK, Stampfer MJ, Rimm E, Spiegelman D, Manson JE, Willett WC. Dietary carotenoids and risk of coronary artery disease in women 1 , 2 , 3. American Journal Of Clinical Nutrition 2003, 77: 1390-1399. PMID: 12791615, DOI: 10.1093/ajcn/77.6.1390.Peer-Reviewed Original ResearchConceptsRisk of CADCoronary artery diseaseArtery diseaseHigh intakePrevention of CADIncident coronary artery diseaseSemiquantitative food frequency questionnaireCAD risk factorsBeta-carotene supplementationFood frequency questionnaireCurrent smoking statusDietary carotenoidsSignificant inverse associationLutein/zeaxanthinHigh blood concentrationsConsumption of carotenoidsCAD riskSmoking statusIncident casesHighest quintileLowest quintileInverse associationRisk factorsDietary intakeBlood concentrations
2002
Intakes of vitamins E and C, carotenoids, vitamin supplements, and PD risk
Zhang SM, Hernán MA, Chen H, Spiegelman D, Willett WC, Ascherio A. Intakes of vitamins E and C, carotenoids, vitamin supplements, and PD risk. Neurology 2002, 59: 1161-1169. PMID: 12391343, DOI: 10.1212/01.wnl.0000028688.75881.12.Peer-Reviewed Original ResearchConceptsRisk of PDVitamin E intakeVitamin EHigh intakeVitamin supplementsE intakeRelative riskHealth StudyHigher dietary vitamin E intakeHigh vitamin E intakePooled multivariate relative risksDietary vitamin E intakeSemiquantitative food frequency questionnaireMultivariate relative riskIncident PD casesNurses' Health StudyFood frequency questionnaireDietary vitamin CDietary vitamin EVitamin C supplementsPathogenesis of PDConsumption of nutsFrequency questionnaireConstituents of foodsHighest quintile
2001
Assessment of Questionnaire Validity for Measuring Total Fat Intake using Plasma Lipid Levels as Criteria
Willett W, Stampfer M, Chu NF, Spiegelman D, Holmes M, Rimm E. Assessment of Questionnaire Validity for Measuring Total Fat Intake using Plasma Lipid Levels as Criteria. American Journal Of Epidemiology 2001, 154: 1107-1112. PMID: 11744515, DOI: 10.1093/aje/154.12.1107.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overBiomarkersBody Mass IndexBody WeightCholesterol, HDLCohort StudiesCross-Sectional StudiesDiet SurveysDietary FatsDietary FiberDietary ProteinsEnergy IntakeExerciseFastingFollow-Up StudiesHumansMaleMiddle AgedProspective StudiesRegression AnalysisReproducibility of ResultsSmokingSurveys and QuestionnairesTriglyceridesConceptsTotal fat intakeFood frequency questionnaireFat intakeTriglyceride levelsFrequency questionnaireDietary fatSemiquantitative food frequency questionnaireHealth Professionals FollowBody mass indexHigh fat intakePlasma lipid levelsMetabolic studiesIntake of proteinCross-sectional analysisProfessionals FollowOverweight menMass indexInverse associationLipid levelsPhysical activityBlood specimensAlcohol consumptionSpecific biomarkersIntakeMultiple regression analysisIntakes of carotenoids, vitamin C, and vitamin E and MS risk among two large cohorts of women
Zhang SM, Hernán MA, Olek MJ, Spiegelman D, Willett WC, Ascherio A. Intakes of carotenoids, vitamin C, and vitamin E and MS risk among two large cohorts of women. Neurology 2001, 57: 75-80. PMID: 11445631, DOI: 10.1212/wnl.57.1.75.Peer-Reviewed Original ResearchConceptsRisk of MSVitamin EVitamin CLarge cohortSemiquantitative food frequency questionnaireRecent case-control studyAssociation of intakeMultivariate relative riskVitamin C intakeFood frequency questionnaireIntake of carotenoidsIntake of fruitsDietary vitamin CTotal energy intakeDietary vitamin E.Case-control studyLutein/zeaxanthinCases of MSFrequency questionnaireC intakeMS riskMultivitamin supplementsAntioxidant nutrientsHighest quintileLowest quintileProspective Study of Zinc Intake and the Risk of Age-Related Macular Degeneration
Cho E, Stampfer M, Seddon J, Hung S, Spiegelman D, Rimm E, Willett W, Hankinson S. Prospective Study of Zinc Intake and the Risk of Age-Related Macular Degeneration. Annals Of Epidemiology 2001, 11: 328-336. PMID: 11399447, DOI: 10.1016/s1047-2797(01)00217-4.Peer-Reviewed Original ResearchConceptsAge-related macular degenerationZinc intakeRelative riskProspective studyLowest quintileMacular degenerationRisk of AMDDiagnosis of AMDSemiquantitative food frequency questionnaireMultivariate relative riskPooled relative riskFood frequency questionnaireLarge prospective studiesDietary zinc intakeVisual acuity lossTotal zinc intakePotential risk factorsRisk of AgeMultivariate adjustmentIncident casesAcuity lossHighest quintileLong-term benefitsRisk factorsZinc supplements
2000
Prospective Study of Alcohol Consumption and the Risk of Age-Related Macular Degeneration
Cho E, Hankinson SE, Willett WC, Stampfer MJ, Spiegelman D, Speizer FE, Rimm EB, Seddon JM. Prospective Study of Alcohol Consumption and the Risk of Age-Related Macular Degeneration. JAMA Ophthalmology 2000, 118: 681-688. PMID: 10815161, DOI: 10.1001/archopht.118.5.681.Peer-Reviewed Original ResearchConceptsAge-related macular degenerationRisk of AMDProspective studyMacular degenerationAlcohol consumptionRelative riskDiagnosis of AMDSemiquantitative food frequency questionnaireMale health professionalsPooled relative riskFood frequency questionnaireModerate alcohol consumptionVisual acuity lossConfidence intervalsRisk of AgeRelationship of alcoholYears of ageAlcohol intakeAcuity lossRisk factorsPooled estimatesFemale nursesHealth professionalsAdditional subjectsWomen
1998
Vitamins A, C and E and the risk of breast cancer: results from a case-control study in Greece
Bohlke K, Spiegelman D, Trichopoulou A, Katsouyanni K, Trichopoulos D. Vitamins A, C and E and the risk of breast cancer: results from a case-control study in Greece. British Journal Of Cancer 1998, 79: 23-29. PMID: 10408688, PMCID: PMC2362172, DOI: 10.1038/sj.bjc.6690006.Peer-Reviewed Original ResearchConceptsΒ-carotene intakeBreast cancer riskCase-control studyBreast cancerOdds ratioCancer riskVitamin ESemiquantitative food frequency questionnaireBreast cancer risk factorsIntake of retinolVitamin CFood frequency questionnaireCancer risk factorsPost-menopausal womenTotal energy intakeΒ-carotene effectPremenopausal womenFrequency questionnaireControl womenVegetable intakeInverse associationRisk factorsDietary compoundsDietary dataSpecific micronutrients
1997
Dietary Fiber, Glycemic Load, and Risk of NIDDM in Men
Salmerón J, Ascherio A, Rimm E, Colditz G, Spiegelman D, Jenkins D, Stampfer M, Wing A, Willett W. Dietary Fiber, Glycemic Load, and Risk of NIDDM in Men. Diabetes Care 1997, 20: 545-550. PMID: 9096978, DOI: 10.2337/diacare.20.4.545.Peer-Reviewed Original ResearchConceptsRisk of NIDDMHigh glycemic loadGlycemic loadCereal fiberRelative riskHigher cereal fiber intakeSemiquantitative food frequency questionnaireCereal fiber intakeLarge glycemic responseDietary glycemic indexFood frequency questionnaireIncidence of NIDDMIntake of carbohydratesTotal energy intakeLow glycemic loadYears of ageDietary fiberFrequency questionnaireIncident casesLowest quintileCardiovascular diseaseFamily historyFiber intakeNIDDMPhysical activity
1996
Prospective Study of Beverage Use and the Risk of Kidney Stones
Curhan G, Willett W, Rimm E, Spiegelman D, Stampfer M. Prospective Study of Beverage Use and the Risk of Kidney Stones. American Journal Of Epidemiology 1996, 143: 240-247. PMID: 8561157, DOI: 10.1093/oxfordjournals.aje.a008734.Peer-Reviewed Original ResearchConceptsFluid intakeKidney stonesStone formationProspective studySemiquantitative food frequency questionnaireBeverage useAdditional fluid intakeFood frequency questionnaireKidney stone riskSymptomatic kidney stonesTotal fluid intakeYears of ageThiazide useFrequency questionnaireStone recurrenceIncident casesType of beverageStone riskDietary intakeDecaffeinated coffeeDietary informationGrapefruit juiceIntakeSpecific beveragesBeverage type