2014
Abstract PR04: Cooperation between Ras network mutations in cancer
Stites E, Trampont P, Haney L, Walk S, Ravichandran K. Abstract PR04: Cooperation between Ras network mutations in cancer. Molecular Cancer Research 2014, 12: pr04-pr04. DOI: 10.1158/1557-3125.rasonc14-pr04.Peer-Reviewed Original ResearchRas signaling networkSignaling networksGenomic dataRAS pathway mutationsRas mutantsNetwork mutationGenomic data setsCancer Cell Line EncyclopediaCancer genome sequencingPathway mutationsTumor suppressor gene NF1Wild-type cellsCancer genomic dataGenome sequenceTumor suppressor gene mutationsCancer Genome AtlasGene NF1Cell-based experimentsDisplay synergyMutational pathwaysRAS networkRas oncogeneCo-occurrenceMutationsRas
2012
Abstract 5104: Identification of key tumorigenic pathways in pancreatic adenocarcinoma patients using massively parallel DNA and RNA sequencing
Liang W, Craig D, Carpten J, Borad M, Demeure M, Weiss G, Kiefer J, Posner R, Hostetter G, Izatt T, Sinari S, Christoforides A, Aldrich J, Kurdoglu A, Phillips L, Benson H, Baker A, Han H, Lake D, Stites E, Ramanathan R, Fonseca R, Stewart A, Hoff D. Abstract 5104: Identification of key tumorigenic pathways in pancreatic adenocarcinoma patients using massively parallel DNA and RNA sequencing. Cancer Research 2012, 72: 5104-5104. DOI: 10.1158/1538-7445.am2012-5104.Peer-Reviewed Original ResearchNext-generation sequencing technologiesWhole-genome sequencingWhole-transcriptome sequencingPancreatic adenocarcinoma patientsChromosomal copy number variantsMassively parallel DNACopy number variantsPancreatic cancer pathwayAdenocarcinoma patientsPancreatic adenocarcinomaGlobal pathway analysisGenome sequenceSequencing technologiesTranscriptome sequencingPinpointing genesAmerican Association for Cancer ResearchKRAS signaling pathwayMultiple genesPoint mutationsRNA sequencingParallel DNASomatic eventsPathway analysisSignaling pathwayCancer pathways