2019
Transcriptome-wide association study identifies new candidate susceptibility genes for glioma
Atkins I, Kinnersley B, Ostrom QT, Labreche K, Il'yasova D, Armstrong GN, Eckel-Passow JE, Schoemaker MJ, Nöthen MM, Barnholtz-Sloan JS, Swerdlow AJ, Simon M, Rajaraman P, Chanock SJ, Shildkraut J, Bernstein JL, Hoffmann P, Jöckel KH, Lai RK, Claus EB, Olson SH, Johansen C, Wrensch MR, Melin B, Jenkins RB, Sanson M, Bondy ML, Houlston RS. Transcriptome-wide association study identifies new candidate susceptibility genes for glioma. Cancer Research 2019, 79: canres.2888.2018. PMID: 30709929, PMCID: PMC6522343, DOI: 10.1158/0008-5472.can-18-2888.Peer-Reviewed Original ResearchConceptsGenome-wide association studiesTranscriptome-wide association studyNovel risk lociRisk lociAssociation studiesCausal genesGenotype-Tissue Expression project dataNew candidate susceptibility genesGlioma risk variantsGWAS-identified variantsGWAS summary statisticsGlioma risk lociBonferroni-corrected significance levelCandidate susceptibility genesGWAS lociNew genesNovel lociGene expressionGenesLociSusceptibility variantsSusceptibility genesRisk variantsGlioma tumorigenesisNon-GBM tumors
2008
Specific Genes Expressed in Association with Progesterone Receptors in Meningioma
Claus EB, Park PJ, Carroll R, Chan J, Black PM. Specific Genes Expressed in Association with Progesterone Receptors in Meningioma. Cancer Research 2008, 68: 314-322. PMID: 18172325, PMCID: PMC3256746, DOI: 10.1158/0008-5472.can-07-1796.Peer-Reviewed Original ResearchConceptsHormone receptor statusPR statusReceptor statusER statusGene expressionMean ageNeurosurgical resectionProgesterone receptorWomen's HospitalClinical markersSurgical specimensExtracellular matrix pathwaysEstrogen hormone receptorsMeningioma casesMeningioma patientsGene expression profiling resultsGrade 1MeningiomasHormone receptorsNeurofibromatosis type 2 geneStrong associationType 2 geneExpression profiling resultsGenetic subgroupsExpression of genes