2020
Rate of true recurrent implantation failure is low: results of three successive frozen euploid single embryo transfers
Pirtea P, De Ziegler D, Tao X, Sun L, Zhan Y, Ayoubi JM, Seli E, Franasiak JM, Scott RT. Rate of true recurrent implantation failure is low: results of three successive frozen euploid single embryo transfers. Fertility And Sterility 2020, 115: 45-53. PMID: 33077239, DOI: 10.1016/j.fertnstert.2020.07.002.Peer-Reviewed Original ResearchConceptsRecurrent implantation failureEuploid single-embryo transferLive birth rateSingle embryo transferImplantation rateImplantation failureEmbryo transferCumulative live birth rateSustained implantation ratesRetrospective cohort studyKaplan-Meier curvesReproductive technology centerDifference of outcomeBirth rateCumulative implantation rateLogistic regression modelsPositive heartbeatClinical pregnancyCohort studyMiscarriage rateMean ageEuploid blastocystsNormal uterusMAIN OUTCOMEGestational carrier
2014
Metabolomic Assessment of Embryo Viability
Uyar A, Seli E. Metabolomic Assessment of Embryo Viability. Seminars In Reproductive Medicine 2014, 32: 141-152. PMID: 24515909, PMCID: PMC4109799, DOI: 10.1055/s-0033-1363556.Peer-Reviewed Original ResearchConceptsSingle embryo transferClinical pregnancyInitial promising resultsPreimplantation embryo metabolismPregnancy rateEmbryo selection processEmbryo viabilityEmbryo transferImplantation potentialSignificant associationConsistent benefitElimination of factorsConsecutive studiesClinical IVF laboratoryMetabolomic assessmentSuccess rateIVF laboratoryCulture mediumInconsistent findingsEmbryo metabolismMetabolomics studiesMetabolomics technologyDevelopmental potentialPrincipal studiesMedia metabolites