Mitochondria as determinants of reproductive senescence and competence: implications for diagnosis of embryo competence in assisted reproduction
Yildirim R, Seli E. Mitochondria as determinants of reproductive senescence and competence: implications for diagnosis of embryo competence in assisted reproduction. Human Reproduction 2024, 39: 2160-2170. PMID: 39066612, DOI: 10.1093/humrep/deae171.Peer-Reviewed Original ResearchMultiple quality control mechanismsMitochondrial unfolded protein responseMitochondrial DNA copy numberUnfolded protein responseQuality control mechanismsDNA copy numberMitochondrial networkRegulate calcium signalingMitochondrial dynamicsReproductive successMitochondrial quantityProtein responseDinucleotide contentModulate apoptosisOxidative phosphorylationCellular pathwaysCopy numberMitochondrial dysfunctionMitochondriaCalcium signalingEmbryo competenceMembrane potentialAssisted reproductionDiagnostic targetsReproductive senescence