2011
The mRNA-Binding Protein HuR is Regulated in the Menstrual Cycle and Repressed in Ectopic Endometrium
Karipcin FS, Ensari TA, Kayisli UA, Guzel E, Kallen CB, Seli E. The mRNA-Binding Protein HuR is Regulated in the Menstrual Cycle and Repressed in Ectopic Endometrium. Reproductive Sciences 2011, 18: 145-155. PMID: 20889954, PMCID: PMC3343139, DOI: 10.1177/1933719110382307.Peer-Reviewed Original ResearchConceptsEctopic endometriumMenstrual cycleSecretory phaseCytokine expressionHuR expressionNormal endometriumCultured endometrial stromal cellsStromal cellsEctopic endometrial cellsEctopic human endometriumMid-menstrual phaseElevated cytokine levelsEndometrial stromal cellsLate secretory phasePathogenesis of endometriosisCultured stromal cellsTumor necrosis factorMessenger RNACytokine levelsEndometrial cellsEutopic endometriumHuman endometriumNecrosis factorEndometriumEndometriosis
2003
Pathogenesis of endometriosis
Seli E, Berkkanoglu M, Arici A. Pathogenesis of endometriosis. Obstetrics And Gynecology Clinics Of North America 2003, 30: 41-61. PMID: 12699257, DOI: 10.1016/s0889-8545(02)00052-9.Peer-Reviewed Original ResearchConceptsEndometrial tissueLocal aromatase activityViable endometrial tissueCases of endometriosisPathogenesis of endometriosisCommon gynecologic disorderRetrograde menstruation theoryRetrograde menstruationGynecologic disordersUterine cavityFallopian tubeEndometrial cellsPeritoneal surfaceAromatase activityPelvic organsPeritoneal cavityLow prevalenceTIMP expressionEndometriosisMenstruationTissueAdditional factorsPathogenesisPrevalenceDisease
1998
Follicular fluid of women with endometriosis stimulates the proliferation of endometrial stromal cells.
Bahtiyar MO, Seli E, Oral E, Senturk LM, Zreik TG, Arici A. Follicular fluid of women with endometriosis stimulates the proliferation of endometrial stromal cells. Human Reproduction 1998, 13: 3492-3495. PMID: 9886538, DOI: 10.1093/humrep/13.12.3492.Peer-Reviewed Original ResearchConceptsEndometrial stromal cellsFollicular fluidPeritoneal fluidEndometrial cellsCell proliferationStromal cellsEndometrial stromal cell culturesFollicular fluid contentEndometrial cell proliferationOocyte retrievalStromal cell culturesPeritoneal environmentCell proliferation assaysEndometriosisGrowth-promoting factorsGrowth-promoting effectProliferation assaysWomenMaximum cell proliferationProliferationCellsCell culturesHigher cell proliferationFluid contentThe role of monocyte chemotactic protein-1 in intraperitoneal adhesion formation.
Zeyneloglu HB, Senturk LM, Seli E, Oral E, Olive DL, Arici A. The role of monocyte chemotactic protein-1 in intraperitoneal adhesion formation. Human Reproduction 1998, 13: 1194-1199. PMID: 9647546, DOI: 10.1093/humrep/13.5.1194.Peer-Reviewed Original ResearchConceptsMCP-1 levelsChemotactic protein-1Enzyme-linked immunosorbent assayIntraperitoneal adhesion formationIntraperitoneal adhesionsPg/Monocyte chemotactic protein-1MCP-1 mRNA expressionNormal fertile womenBilateral tubal ligationProtein 1MCP-1 proteinAdhesion formationGroup of womenWound repair modelPelvic adhesionsFertile womenMononuclear cellsPeritoneal injuryMCP-1Tubal ligationReproductive ageEndometriosisBiopsy samplesPatients