2020
Shorter telomere length of white blood cells is associated with higher rates of aneuploidy among infertile women undergoing in vitro fertilization
Hanson BM, Tao X, Zhan Y, Kim JG, Klimczak AM, Herlihy NS, Scott RT, Seli E. Shorter telomere length of white blood cells is associated with higher rates of aneuploidy among infertile women undergoing in vitro fertilization. Fertility And Sterility 2020, 115: 957-965. PMID: 33272640, DOI: 10.1016/j.fertnstert.2020.09.164.Peer-Reviewed Original ResearchConceptsWhite blood cellsPatient ageInfertile womenCumulus cellsBlood cellsEmbryonic aneuploidyPeak estradiol levelsAntimüllerian hormone levelsProspective cohort studyTelomere lengthNumber of oocytesShorter telomere lengthReal-time polymerase chain reactionQuantitative real-time polymerase chain reactionHigh rateWarrants further investigationTelomere length assessmentSignificant overlap existsCohort studyOocyte retrievalSingle centerEstradiol levelsInfertile populationMaternal agePolymerase chain reaction
2016
Cross-Talk Between FSH and Endoplasmic Reticulum Stress: A Mutually Suppressive Relationship
Babayev E, Lalioti MD, Favero F, Seli E. Cross-Talk Between FSH and Endoplasmic Reticulum Stress: A Mutually Suppressive Relationship. Reproductive Sciences 2016, 23: 352-364. PMID: 26342052, PMCID: PMC5933091, DOI: 10.1177/1933719115602770.Peer-Reviewed Original ResearchConceptsFollicle stimulating hormonePregnant mare serum gonadotropinMouse granulosa cellsGranulosa cellsFSH responseSerum gonadotropinFSH stimulationER stressStress-induced cellsPrimary mouse granulosa cellsUntreated granulosa cellsMessenger RNA levelsCalcium adenosine triphosphataseEndoplasmic reticulum stressEstradiol levelsMice 24Estradiol productionIntraperitoneal injectionStimulating hormoneAromatase expressionTP treatmentReticulum stressRNA levelsER stress-associated genesProtein levels