Mitochondrial Stress Response Gene Clpp Is Not Required for Granulosa Cell Function
Esencan E, Cozzolino M, Imamoglu G, Seli E. Mitochondrial Stress Response Gene Clpp Is Not Required for Granulosa Cell Function. Antioxidants 2020, 10: 1. PMID: 33374937, PMCID: PMC7821922, DOI: 10.3390/antiox10010001.Peer-Reviewed Original ResearchMitochondrial unfolded protein responseUnfolded mitochondrial proteinsLoss of ClpPGerminal vesicleUnfolded protein responseCell functionCumulus cell functionGranulosa/cumulus cellsMitochondrial proteinsClpP deletionClpPProtein responseGermline deletionMetabolic stressGranulosa cell functionDeletionUPRCumulus cellsMice resultsSimilar numberMII oocytesFemale miceWild-type miceEarly antralCells