2024
Evolution of biotechnological advances and regenerative therapies for endometrial disorders: a systematic review
Rodríguez-Eguren A, Bueno-Fernandez C, Gómez-Álvarez M, Francés-Herrero E, Pellicer A, Bellver J, Seli E, Cervelló I. Evolution of biotechnological advances and regenerative therapies for endometrial disorders: a systematic review. Human Reproduction Update 2024, 30: 584-613. PMID: 38796750, PMCID: PMC11369227, DOI: 10.1093/humupd/dmae013.Peer-Reviewed Original ResearchPlatelet-rich plasmaAsherman's syndromeEndometrial atrophyIntrauterine adhesionsThin endometriumRegenerative therapyMesenchymal stem cellsEndometrial pathologyStem cellsPreclinical modelsEndometrial disordersClinical studiesRisk of poor pregnancy outcomesGrowth factorTreated with surgeryStem cell-based treatmentsPoor pregnancy outcomesTissue repairMaintenance of pregnancyPersonalized treatment regimensImprove reproductive outcomesCell-based treatmentsSystematic reviewHuman bone marrowEndometrial proliferation
2014
mRNA-Binding Protein TIA-1 Reduces Cytokine Expression in Human Endometrial Stromal Cells and Is Down-Regulated in Ectopic Endometrium
Karalok HM, Aydin E, Saglam O, Torun A, Guzeloglu-Kayisli O, Lalioti MD, Kristiansson H, Duke CM, Choe G, Flannery C, Kallen CB, Seli E. mRNA-Binding Protein TIA-1 Reduces Cytokine Expression in Human Endometrial Stromal Cells and Is Down-Regulated in Ectopic Endometrium. The Journal Of Clinical Endocrinology & Metabolism 2014, 99: e2610-e2619. PMID: 25140393, PMCID: PMC4255110, DOI: 10.1210/jc.2013-3488.Peer-Reviewed Original ResearchConceptsHuman endometrial stromal cellsTNF-α expressionTIA-1 expressionEndometrial stromal cellsIL-6Pathogenesis of endometriosisMenstrual cycleTIA-1Endometrial tissueEctopic endometriumImmune factorsHistological scoresCultured human endometrial stromal cellsSteroid hormonesStromal cellsGrowth factorElevated IL-6Ectopic endometrial tissueNormal menstrual cycleEutopic endometrial tissuesGrowth factor expressionT-cell intracellular antigenEndometrial cytokinesEndometrial functionControl women