Pathogenesis of endometriosis
Seli E, Berkkanoglu M, Arici A. Pathogenesis of endometriosis. Obstetrics And Gynecology Clinics Of North America 2003, 30: 41-61. PMID: 12699257, DOI: 10.1016/s0889-8545(02)00052-9.Peer-Reviewed Original ResearchConceptsEndometrial tissueLocal aromatase activityViable endometrial tissueCases of endometriosisPathogenesis of endometriosisCommon gynecologic disorderRetrograde menstruation theoryRetrograde menstruationGynecologic disordersUterine cavityFallopian tubeEndometrial cellsPeritoneal surfaceAromatase activityPelvic organsPeritoneal cavityLow prevalenceTIMP expressionEndometriosisMenstruationTissueAdditional factorsPathogenesisPrevalenceDiseaseEndometriosis: Interaction of Immune and Endocrine Systems
Seli E, Arici A. Endometriosis: Interaction of Immune and Endocrine Systems. Seminars In Reproductive Medicine 2003, 21: 135-144. PMID: 12917783, DOI: 10.1055/s-2003-41320.Peer-Reviewed Original ResearchConceptsEndometriotic implantsRetrograde menstruationNatural killer cell activityGonadotropin-releasing hormone agonistKiller cell activityObserved clinical improvementCases of endometriosisHumoral immune responseDevelopment of endometriosisCommon gynecologic disorderEndometriosis implantsPelvic painClinical improvementGnRH agonistImmunologic alterationsHormone agonistEndometrial tissueGynecologic disordersHumoral immunityImmunomodulatory effectsUterine cavityImmune cellsMenstrual debrisPeritoneal fluidEndometrial cells