2022
The use of intraovarian injection of autologous platelet rich plasma (PRP) in patients with poor ovarian response and premature ovarian insufficiency
Herlihy NS, Seli E. The use of intraovarian injection of autologous platelet rich plasma (PRP) in patients with poor ovarian response and premature ovarian insufficiency. Current Opinion In Obstetrics & Gynecology 2022, 34: 133-137. PMID: 35645011, DOI: 10.1097/gco.0000000000000784.Peer-Reviewed Original ResearchConceptsPoor ovarian responsePlatelet-rich plasmaPrimary ovarian insufficiencyPoor prognosis patientsPrognosis patientsOvarian reserveIntraovarian injectionOvarian responseOvarian insufficiencyLive birthsRich plasmaEffect of PRPAutologous platelet-rich plasmaIntra-ovarian injectionPremature ovarian insufficiencyMultiple live birthsProspective trialCase seriesClinical trialsPatient's abilityNovel treatmentsPatientsEmbryo yieldInsufficiencyTreatmentOvarian reserve parameters and IVF outcomes in 510 women with poor ovarian response (POR) treated with intraovarian injection of autologous platelet rich plasma (PRP)
Cakiroglu Y, Yuceturk A, Karaosmanoglu O, Kopuk SY, Korun ZEU, Herlihy N, Scott RT, Tiras B, Seli E. Ovarian reserve parameters and IVF outcomes in 510 women with poor ovarian response (POR) treated with intraovarian injection of autologous platelet rich plasma (PRP). Aging 2022, 14: 2513-2523. PMID: 35320118, PMCID: PMC9004561, DOI: 10.18632/aging.203972.Peer-Reviewed Original ResearchConceptsPoor ovarian responseOvarian reserve parametersPlatelet-rich plasmaAutologous platelet-rich plasmaReserve parametersIntraovarian injectionIVF outcomesOvarian responsePRP treatmentProspective randomized clinical trialsRich plasmaHigher serum AMHLower serum FSHUnderwent embryo transferReproductive-age womenRandomized clinical trialsWide clinical applicationPOSEIDON criteriaSerum AMHSerum FSHPRP injectionClinical efficacyAge womenClinical trialsPregnancy rate
2021
Emerging follicular activation strategies to treat women with poor ovarian response and primary ovarian insufficiency
Reig A, Herraiz S, Pellicer A, Seli E. Emerging follicular activation strategies to treat women with poor ovarian response and primary ovarian insufficiency. Current Opinion In Obstetrics & Gynecology 2021, 33: 241-248. PMID: 33896920, DOI: 10.1097/gco.0000000000000703.Peer-Reviewed Original ResearchConceptsPoor ovarian responsePrimary ovarian insufficiencyLive birthsOngoing pregnancyOvarian responseOvarian insufficiencyAutologous platelet-rich plasmaBone marrow transplantFemale reproductive agingPlatelet-rich plasmaIntraovarian injectionOvarian transplantationMarrow transplantReproductive agingFertility treatmentReproductive medicineWomenPregnancyBirthInsufficiencyPrevious reportsPreliminary studyMechanical disruptionAkt stimulationCutting-edge strategies
2020
Effects of intraovarian injection of autologous platelet rich plasma on ovarian reserve and IVF outcome parameters in women with primary ovarian insufficiency
Cakiroglu Y, Saltik A, Yuceturk A, Karaosmanoglu O, Kopuk SY, Scott RT, Tiras B, Seli E. Effects of intraovarian injection of autologous platelet rich plasma on ovarian reserve and IVF outcome parameters in women with primary ovarian insufficiency. Aging 2020, 12: 10211-10222. PMID: 32507764, PMCID: PMC7346073, DOI: 10.18632/aging.103403.Peer-Reviewed Original ResearchConceptsAutologous platelet-rich plasmaPrimary ovarian insufficiencyPlatelet-rich plasmaIVF outcome parametersAntral follicle countIntraovarian injectionOvarian reservePRP injectionAntimullerian hormoneOutcome parametersOvarian insufficiencyRich plasmaSerum antimullerian hormoneUnderwent embryo transferExperimental treatment optionsESHRE criteriaSustained implantationOvarian stimulationSerum follicleFollicle countPRP treatmentTreatment optionsFertilization outcomeAntral folliclesEmbryo transfer