A review of the pathophysiology of recurrent implantation failure
Franasiak JM, Alecsandru D, Forman EJ, Gemmell LC, Goldberg JM, Llarena N, Margolis C, Laven J, Schoenmakers S, Seli E. A review of the pathophysiology of recurrent implantation failure. Fertility And Sterility 2021, 116: 1436-1448. PMID: 34674825, DOI: 10.1016/j.fertnstert.2021.09.014.Peer-Reviewed Original ResearchConceptsRecurrent implantation failureImplantation failureMaternal immune systemReproductive tract microbiomeLack of implantationEndometrial synchronyHematologic factorsAnatomic factorsEndocrine milieuReceptive endometriumMaternal interfaceEmbryo transferImmune systemApparent treatmentCompetent blastocystClinical phenomenaHuman reproductionPotential causesImplantationFailureReviewCross talkEndometriumPatientsFactors