mRNA-Binding Protein ZFP36 Is Expressed in Atherosclerotic Lesions and Reduces Inflammation in Aortic Endothelial Cells
Zhang H, Taylor WR, Joseph G, Caracciolo V, Gonzales DM, Sidell N, Seli E, Blackshear PJ, Kallen CB. mRNA-Binding Protein ZFP36 Is Expressed in Atherosclerotic Lesions and Reduces Inflammation in Aortic Endothelial Cells. Arteriosclerosis Thrombosis And Vascular Biology 2013, 33: 1212-1220. PMID: 23559629, PMCID: PMC3844532, DOI: 10.1161/atvbaha.113.301496.Peer-Reviewed Original ResearchConceptsVascular endothelial cellsEndothelial cellsAortic endothelial cellsAtherosclerotic lesionsFoam cellsAnti-inflammatory effectsHuman aortic endothelial cellsNuclear factor-κB transcriptional activationLow-density lipoproteinMacrophage foam cellsZinc finger protein 36Vascular inflammationAngiotensin IIInflammatory cytokinesCytokine mRNAZFP36 expressionBacterial lipopolysaccharideHealthy aortaInflammationTarget cellsLesionsZFP36Protein 36CellsMRNA transcripts