Estradiol suppresses vascular monocyte chemotactic protein-1 expression during early atherogenesis
Seli E, Kayisli UA, Selam B, Seli M, Arici A. Estradiol suppresses vascular monocyte chemotactic protein-1 expression during early atherogenesis. American Journal Of Obstetrics And Gynecology 2002, 187: 1544-1549. PMID: 12501061, DOI: 10.1067/mob.2002.127306.Peer-Reviewed Original ResearchConceptsMonocyte chemotactic protein-1 expressionChemotactic protein-1 expressionProtein-1 expressionLipid depositionSerum total cholesterol concentrationVascular lipid depositionProtein 1 antibodyAorta of animalsTotal cholesterol concentrationDevelopment of atherosclerosisSmooth muscle cellsPlacebo pelletsAtherogenic stimuliDeficient miceMacrophage recruitmentEarly atherogenesisImmunohistochemical analysisTreatment groupsC57BL/6 backgroundCholesterol concentrationsMuscle cellsArterial wallB stainingAortaEstradiol