2024
The role of mitochondrial dynamics in oocyte and early embryo development
Yildirim R, Seli E. The role of mitochondrial dynamics in oocyte and early embryo development. Seminars In Cell And Developmental Biology 2024, 159: 52-61. PMID: 38330625, DOI: 10.1016/j.semcdb.2024.01.007.Peer-Reviewed Original ResearchMitochondrial dynamicsRegulating mitochondrial dynamicsImpaired mitochondrial dynamicsMorphology of mitochondriaMitochondria importDynamic organellesMitochondrial networkDysfunctional mitochondriaEmbryo developmentCellular processesPre-implantation embryo developmentPhospholipid synthesisMitochondriaHuman diseasesMitochondrial dysfunctionInnate immunityOlder reproductive age womenCell typesReproductive processesAffecting oocyte qualityCalcium regulationSuccess of pregnancyFemale reproductive healthReproductive age womenPost-fertilization
2018
The role of mitochondrial activity in female fertility and assisted reproductive technologies: overview and current insights
Cecchino GN, Seli E, Alves da Motta E, García-Velasco J. The role of mitochondrial activity in female fertility and assisted reproductive technologies: overview and current insights. Reproductive BioMedicine Online 2018, 36: 686-697. PMID: 29598846, DOI: 10.1016/j.rbmo.2018.02.007.Peer-Reviewed Original ResearchConceptsMetabolic stress modelsMitochondrial functionFemale fertilityFemale reproductive processesPoor outcomeReplacement therapyOvarian agingMitochondrial DNA contentInfertility treatmentTherapeutic attemptsOocyte qualityClinical implicationsEmbryo potentialOocyte maturationReproductive processesPrecursor cellsEarly embryo developmentReproductive technologiesDisease-causing mutationsMitochondrial capacityRole of mitochondriaMitochondrial impactCurrent insightsTrophectoderm cellsWomen