2019
Cumulus cells have longer telomeres than leukocytes in reproductive-age women
Lara-Molina EE, Franasiak JM, Marin D, Tao X, Díaz-Gimeno P, Florensa M, Martin M, Seli E, Pellicer A. Cumulus cells have longer telomeres than leukocytes in reproductive-age women. Fertility And Sterility 2019, 113: 217-223. PMID: 31594634, DOI: 10.1016/j.fertnstert.2019.08.089.Peer-Reviewed Original ResearchConceptsLeukocyte telomere lengthGranulosa cellsCumulus cellsTelomere lengthAssisted reproductive technology centerRelative leukocyte telomere lengthProspective noninterventional studyAntimüllerian hormone levelsAntral follicle countReproductive-age womenReproductive technology centerLonger telomeresNoninterventional studyFollicle countMean ageHormone levelsFollicular environmentMAIN OUTCOMEMature folliclesStudy subjectsSignificant associationFollicular cellsMean numberMature oocytesSignificant differences
2014
Metabolomic Assessment of Embryo Viability
Uyar A, Seli E. Metabolomic Assessment of Embryo Viability. Seminars In Reproductive Medicine 2014, 32: 141-152. PMID: 24515909, PMCID: PMC4109799, DOI: 10.1055/s-0033-1363556.Peer-Reviewed Original ResearchConceptsSingle embryo transferClinical pregnancyInitial promising resultsPreimplantation embryo metabolismPregnancy rateEmbryo selection processEmbryo viabilityEmbryo transferImplantation potentialSignificant associationConsistent benefitElimination of factorsConsecutive studiesClinical IVF laboratoryMetabolomic assessmentSuccess rateIVF laboratoryCulture mediumInconsistent findingsEmbryo metabolismMetabolomics studiesMetabolomics technologyDevelopmental potentialPrincipal studiesMedia metabolites