Analysis of accessible chromatin landscape in the inner cell mass and trophectoderm of human blastocysts
Yang M, Tao X, Titus S, Zhao T, Scott RT, Seli E. Analysis of accessible chromatin landscape in the inner cell mass and trophectoderm of human blastocysts. Molecular Human Reproduction 2020, 26: 702-711. PMID: 32663300, DOI: 10.1093/molehr/gaaa048.Peer-Reviewed Original ResearchMeSH KeywordsAdultBlastocystBlastocyst Inner Cell MassCells, CulturedChromatinChromatin Assembly and DisassemblyDNA, IntergenicEctodermEmbryonic DevelopmentFemaleHumansPromoter Regions, GeneticConceptsInner cell massHuman preimplantation embryosEpigenetic regulationPreimplantation embryosCell lineage specificationChromatin accessibility landscapeAccessible chromatin landscapePreimplantation human blastocystsEarly embryonic developmentTranscription start siteCell massEarly embryo developmentHuman blastocystsDistal regionChromatin landscapeAccessible chromatinLineage specificationChromatin structureLow DNA inputATAC-seqTrophectoderm differentiationChromosome reorganizationAccessibility landscapeHuman embryonic materialEmbryonic development