2007
Estrogen increases apoptosis in the arterial wall in a murine atherosclerosis model
Seli E, Guzeloglu-Kayisli O, Kayisli UA, Kizilay G, Arici A. Estrogen increases apoptosis in the arterial wall in a murine atherosclerosis model. Fertility And Sterility 2007, 88: 1190-1196. PMID: 17498707, DOI: 10.1016/j.fertnstert.2007.01.132.Peer-Reviewed Original ResearchConceptsHigh-cholesterol dietMurine atherosclerosis modelAtherosclerotic plaque formationCholesterol dietFemale LDLAtherosclerosis modelPlaque formationArterial wallPlacebo-treated miceMitotic activityEffects of estrogenEffects of ovariectomyAtherosclerotic plaque developmentVascular effectsFemale miceMAIN OUTCOMEVascular apoptosisC57BL/6 backgroundPlaque developmentAortic wallLDLLDL receptorMice resultsMiceDNA strand breaks
2002
Estradiol suppresses vascular monocyte chemotactic protein-1 expression during early atherogenesis
Seli E, Kayisli UA, Selam B, Seli M, Arici A. Estradiol suppresses vascular monocyte chemotactic protein-1 expression during early atherogenesis. American Journal Of Obstetrics And Gynecology 2002, 187: 1544-1549. PMID: 12501061, DOI: 10.1067/mob.2002.127306.Peer-Reviewed Original ResearchConceptsMonocyte chemotactic protein-1 expressionChemotactic protein-1 expressionProtein-1 expressionLipid depositionSerum total cholesterol concentrationVascular lipid depositionProtein 1 antibodyAorta of animalsTotal cholesterol concentrationDevelopment of atherosclerosisSmooth muscle cellsPlacebo pelletsAtherogenic stimuliDeficient miceMacrophage recruitmentEarly atherogenesisImmunohistochemical analysisTreatment groupsC57BL/6 backgroundCholesterol concentrationsMuscle cellsArterial wallB stainingAortaEstradiol