2018
A tissue-based draft map of the murine MHC class I immunopeptidome
Schuster H, Shao W, Weiss T, Pedrioli P, Roth P, Weller M, Campbell D, Deutsch E, Moritz R, Planz O, Rammensee H, Aebersold R, Caron E. A tissue-based draft map of the murine MHC class I immunopeptidome. Scientific Data 2018, 5: 180157. PMID: 30084848, PMCID: PMC6080492, DOI: 10.1038/sdata.2018.157.Peer-Reviewed Original ResearchConceptsMHC class IClass IMurine MHC class IPotential tumor-associated antigenMajor histocompatibility complex class IHistocompatibility complex class ITumor-associated antigensComplex class IC57BL/6 miceT cellsTranslational immunologyCancer modelImmune systemNormal tissuesMS injectionMost tissuesTissueInitial qualitative dataTotal numberPeptidesCD8AtlasAntigenMice
2008
The MHC class I peptide repertoire is molded by the transcriptome
Fortier M, Caron E, Hardy M, Voisin G, Lemieux S, Perreault C, Thibault P. The MHC class I peptide repertoire is molded by the transcriptome. Journal Of Experimental Medicine 2008, 205: 595-610. PMID: 18299400, PMCID: PMC2275383, DOI: 10.1084/jem.20071985.Peer-Reviewed Original ResearchMeSH KeywordsAllelesAmino Acid SequenceAnimalsCell LineCell Line, TumorComputational BiologyGene Expression ProfilingGenes, MHC Class IHistocompatibility Antigens Class IMiceMultiprotein ComplexesOligonucleotide Array Sequence AnalysisPeptidesProtein BindingRNA, MessengerTandem Mass SpectrometryT-LymphocytesTransfectionConceptsMIP repertoireCyclin/cyclin-dependent kinasePrimary mouse thymocytesCyclin-dependent kinasesMass spectrometry approachMouse thymocytesAbundant transcriptsGlobal profilingHigh-throughput analysisPosttranscriptional mechanismsNeoplastic thymocytesRelative abundanceTranscriptomeMHC class INeoplastic transformationCancer cellsMHC IMolecular compositionPeptidomics dataRepertoirePeptidesClass IMajor histocompatibility complex I moleculesThymocytesHelicases