2008
The MHC class I peptide repertoire is molded by the transcriptome
Fortier M, Caron E, Hardy M, Voisin G, Lemieux S, Perreault C, Thibault P. The MHC class I peptide repertoire is molded by the transcriptome. Journal Of Experimental Medicine 2008, 205: 595-610. PMID: 18299400, PMCID: PMC2275383, DOI: 10.1084/jem.20071985.Peer-Reviewed Original ResearchMeSH KeywordsAllelesAmino Acid SequenceAnimalsCell LineCell Line, TumorComputational BiologyGene Expression ProfilingGenes, MHC Class IHistocompatibility Antigens Class IMiceMultiprotein ComplexesOligonucleotide Array Sequence AnalysisPeptidesProtein BindingRNA, MessengerTandem Mass SpectrometryT-LymphocytesTransfectionConceptsMIP repertoireCyclin/cyclin-dependent kinasePrimary mouse thymocytesCyclin-dependent kinasesMass spectrometry approachMouse thymocytesAbundant transcriptsGlobal profilingHigh-throughput analysisPosttranscriptional mechanismsNeoplastic thymocytesRelative abundanceTranscriptomeMHC class INeoplastic transformationCancer cellsMHC IMolecular compositionPeptidomics dataRepertoirePeptidesClass IMajor histocompatibility complex I moleculesThymocytesHelicases
2005
Identification of two distinct intracellular localization signals in STT3-B
Caron É, Côté C, Parisien M, Major F, Perreault C. Identification of two distinct intracellular localization signals in STT3-B. Archives Of Biochemistry And Biophysics 2005, 445: 108-114. PMID: 16297371, DOI: 10.1016/j.abb.2005.10.007.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsCell LineChlorocebus aethiopsComputational BiologyConserved SequenceEndoplasmic ReticulumHumansIsoenzymesMembrane ProteinsMiceMicroscopy, Electron, TransmissionMolecular Sequence DataNuclear Localization SignalsPhylogenyProtein Structure, TertiaryRecombinant Fusion ProteinsSequence Homology, Amino AcidConceptsBipartite nuclear targeting sequenceRemarkable evolutionary conservationNuclear targeting sequenceN-glycosylation processIntracellular localization signalsC-terminal domainLast transmembrane segmentAmino acid sequenceSTT3 subunitEvolutionary conservationTargeting sequenceLocalization signalOligosaccharyltransferase complexTopogenic determinantsTransmembrane segmentsNucleolar localizationSTT3Reporter proteinTM segmentsTerminal tailAcid sequenceHomo sapiensLatter sequenceCritical roleSequence