2014
Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens
Gubin MM, Zhang X, Schuster H, Caron E, Ward JP, Noguchi T, Ivanova Y, Hundal J, Arthur CD, Krebber WJ, Mulder GE, Toebes M, Vesely MD, Lam SS, Korman AJ, Allison JP, Freeman GJ, Sharpe AH, Pearce EL, Schumacher TN, Aebersold R, Rammensee HG, Melief CJ, Mardis ER, Gillanders WE, Artyomov MN, Schreiber RD. Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens. Nature 2014, 515: 577-581. PMID: 25428507, PMCID: PMC4279952, DOI: 10.1038/nature13988.Peer-Reviewed Original Research
2013
The stress model of chronic pain: evidence from basal cortisol and hippocampal structure and function in humans
Vachon-Presseau E, Roy M, Martel M, Caron E, Marin M, Chen J, Albouy G, Plante I, Sullivan M, Lupien S, Rainville P. The stress model of chronic pain: evidence from basal cortisol and hippocampal structure and function in humans. Brain 2013, 136: 815-827. PMID: 23436504, DOI: 10.1093/brain/aws371.Peer-Reviewed Original ResearchConceptsChronic back painChronic painHippocampal volumeBack painControl subjectsParahippocampal gyrusPain-evoked activityPersistent pain statesAnterior parahippocampal gyrusHealthy control subjectsSmaller hippocampal volumesChronic pain intensityEndocrine stress responsePain statesPain intensityPain responseBasal cortisolPainHippocampal structureCortisol levelsMaladaptive physiological responsesHigher cortisolHippocampal complexConsecutive daysPatients
2011
The multilevel organization of vicarious pain responses: Effects of pain cues and empathy traits on spinal nociception and acute pain
VachonPresseau E, Martel M, Roy M, Caron E, Jackson P, Rainville P. The multilevel organization of vicarious pain responses: Effects of pain cues and empathy traits on spinal nociception and acute pain. Pain 2011, 152: 1525-1531. PMID: 21439727, DOI: 10.1016/j.pain.2011.02.039.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAnalysis of VarianceCuesElectric StimulationElectromyographyEmpathyFacial ExpressionFemaleHumansImaginationInterpersonal RelationsMalePainPain MeasurementPain PerceptionPhotic StimulationPsychophysicsReflexRegression AnalysisSural NerveSurveys and QuestionnairesYoung AdultConceptsVicarious painPain picturesPainful facial expressionsNociceptive flexion reflexEmpathic traitsEmpathy traitsEmotional informationPerceptual processesEmpathic responsesBrain systemsPain cuesFacial expressionsComparable pain intensityNeural systemsAltruistic behaviorPriming processPain intensityEmpathyPain perceptionMultilevel organizationFacilitationTranscutaneous electrical stimulationPain facilitationAcute painSural nerve