Localized 1H NMR measurements of 2‐pyrrolidinone in human brain in vivo
Hyder F, Petroff O, Mattson R, Rothman D. Localized 1H NMR measurements of 2‐pyrrolidinone in human brain in vivo. Magnetic Resonance In Medicine 1999, 41: 889-896. PMID: 10332870, DOI: 10.1002/(sici)1522-2594(199905)41:5<889::aid-mrm6>3.0.co;2-r.Peer-Reviewed Original ResearchGABA Changes with Vigabatrin in the Developing Human Brain
Novotny E, Hyder F, Shevell M, Rothman D. GABA Changes with Vigabatrin in the Developing Human Brain. Epilepsia 1999, 40: 462-466. PMID: 10219272, DOI: 10.1111/j.1528-1157.1999.tb00741.x.Peer-Reviewed Original ResearchConceptsBrain GABA levelsGABA levelsBrain GABAVGB treatmentRole of GABASeizure controlGABA changesSeizure susceptibilityPediatric epilepsyEpileptic focusOccipital lobeNervous systemEpileptic regionsVigabatrinEpilepsyGABAGABA metabolismTreatmentAge 1Noninvasive measurementHuman brainSubjectsDrugsFivefold increaseChildren